Oliveira, Paulo J.

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Credit Name
Oliveira, Paulo J.
 
Name
Oliveira, Paulo J.
 
Variants
Oliveira, Paulo J.
Oliveira, Paulo
 
 
Personal Site
http://www.cnbc.pt/research/department_group_show.asp?iddep=1138&idgrp=1141
 
Email
pauloliv@cnc.uc.pt
 
Other emails
 
 
Ciência ID
 
Researcher ID
 
Status
UC Researcher
Biography
Paulo J. Oliveira is currently Principal Investigator at the CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Portugal, and Invited Assistant Professor in the same University. He is the current leader of the “Mitochondria, Metabolism and Disease” group (shorturl.at/rsLRZ). He received his Bachelor of Science in Biochemistry from the University de Coimbra in 1999. In 2003, he completed his PhD in Cellular Biology from the same University. After completing his doctorate, Paulo Oliveira spent more than three years working at the Medical School of the University of Minnesota, Duluth, USA, where he collaborated with several researchers and contributed to the publication of several peer-reviewed manuscripts. Paulo Oliveira current research interests focus on mitochondrial biology, investigating the alteration of cardiac mitochondrial function by physical activity and diet, cardiac mitochondrial dysfunction and cell death caused by anti-neoplastic agents, mitochondrial alterations during cancer stem cell differentiation and carcinogenesis or rational designing of mitochondria-directed antioxidants. Paulo has about 260 peer-reviewed publications and a large number of collaborations in Europe, Africa and in the USA. He has also received several prizes from the Portuguese Cardiology Society for his work on cardiac mitochondrial research. Besides research, Paulo Oliveira is often involved in teaching at the Department of Life Sciences, University of Coimbra, as well as in other Universities in Portugal and elsewhere, besides in numerous science communication activities. Of importance, he has maintained a consistent primary role in the organization of national and international scientific meetings, including the International Courses in Toxicology (2005-2010 in Coimbra), Annual Meeting of the European Society for Clinical Investigation (2013, Albufeira, Portugal and 2019, Coimbra, Portugal), the 2014 Meeting of the Portuguese Biochemical Society, and FEBS Advanced Lecture Courses in Oncometabolism (2017, Figueira da Foz, Portugal and 2019 Luso, Portugal). Since May 2019, Paulo Oliveira is also President of the European Society for Clinical Investigation, after being its Vice-President for 2 years. Paulo Oliveira has also been reviewer for more than 40 different scientific journals and over 10 different funding agencies, including the European Commission (Research Executive Agency) and the Portuguese Foundation for Science and Technology. His research group is supported by competitive national and international funding agencies, including the Portuguese Foundation for Science and Technology, the European Commission, and private foundations.
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Publications

Results 1-135 of 135 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
12012Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial functionMota, Paula C. ; Tavares, Renata S. ; Cordeiro, Marília ; Pereira, Susana P. ; Publicover, Stephen J. ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
22021Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal Extracts Decrease Doxorubicin Cytotoxicity on H9c2 CardiomyoblastsMoukette, Bruno ; Castelão-Baptista, José P. ; Ferreira, Luciana L. ; Silva, Ana M. ; Simões, Rui F. ; Cabral, Célia ; Pieme, Constant A.; Ngogang, Jeanne Y.; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
31-Sep-2017Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicityFerreira, André ; Cunha-Oliveira, Teresa ; Simões, Rui F. ; Carvalho, Filipa S. ; Burgeiro, Ana ; Nordgren, Kendra ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
42015Analysis of pro-apoptotic protein trafficking to and from mitochondriaVega-Naredo, Ignacio ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
516-Aug-2019Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver DiseaseFontes, Adriana ; Alemany-Pagès, Mireia; Oliveira, Paulo J. ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa articleopenAccess
62014Berberine modulation on doxorubicin-induced cell death and auto phagyMartins, Tatiana Isabel Rodrigues masterThesisopenAccess
7Nov-2017Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblastsCoelho, Ana R. ; Martins, Tatiana R. ; Couto, Renata ; Deus, Cláudia ; Pereira, Cláudia V. ; Simões, Rui F. ; Rizvanov, Albert A. ; Silva, Filomena ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. ; Serafim, Teresa L. articleopenAccess
8Sep-2000Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapyRolo, Anabela P. ; Oliveira, Paulo J. ; Moreno, António J. M. ; Palmeira, Carlos M. articleopenAccess
92005Bile acids are toxic for isolated cardiac mitochondriaFerreira, Manuela ; Coxito, Pedro ; Sardão, Vilma ; Palmeira, Carlos ; Oliveira, Paulo articleopenAccess
102002Caffeine Enhances the Calcium-Dependent Cardiac Mitochondrial Permeability Transition: Relevance for Caffeine ToxicitySardão, Vilma A. ; Oliveira, Paulo J. ; Moreno, António J. M. articleopenAccess
112004Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic ratOliveira, Paulo J. ; Esteves, Telma C. ; Seiça, Raquel ; Moreno, António J. M. ; Santos, Maria S. articleopenAccess
12Sep-2009Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?Pereira, Susana P. ; Pereira, Gonçalo C. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
132021Cancer cell metabolism: Rewiring the mitochondrial hubOliveira, Gabriela L.; Coelho, Ana R. ; Marques, Ricardo; Oliveira, Paulo J. articleopenAccess
142016Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial functionPereira, Gonçalo C. ; Pereira, Susana P. ; Tavares, Ludgero C. ; Carvalho, Filipa S. ; Magalhães-Novais, Sílvia ; Barbosa, Inês A. ; Santos, Maria S. ; Bjork, James ; Moreno, António J. ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
153-Feb-2003Cardiac mitochondrial function : studies on the impact of disease conditions and on the protection afforded by carvedilolOliveira, Paulo Jorge Gouveia Simões da Silva doctoralThesisembargoedAccess
162014Cardiolipin content in P19 embryonal carcinoma cellsNovais, Sílvia Carina Magalhães masterThesisopenAccess
171-Jan-2014Carriers for metal complexes on tumour cells: the effect of cyclodextrins vs CNTs on the model guest phenanthroline-5,6-dione trithiacyclononane ruthenium(II) chlorideBraga, Susana S. ; Marques, Joana ; Heister, Elena ; Diogo, Cátia V. ; Oliveira, Paulo J. ; Paz, Filipe A. Almeida ; Santos, Teresa M. ; Marques, Maria Paula M. articleopenAccess
182000Carvedilol Inhibits the Exogenous NADH Dehydrogenase in Rat Heart MitochondriaOliveira, Paulo J. ; Santos, Dario J. ; Moreno, António J. M. articleopenAccess
192004Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanismOliveira, Paulo ; Esteves, Telma ; Rolo, Anabela ; Palmeira, Carlos ; Moreno, António articleopenAccess
202001Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidaseOliveira, Paulo ; Rolo, Anabela ; Palmeira, Carlos ; Moreno, António articleopenAccess
212004Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicityOliveira, Paulo J. ; Bjork, James A. ; Santos, Maria S. ; Leino, Richard L. ; Froberg, M. Kent ; Moreno, António J. ; Wallace, Kendall B. articleopenAccess
22Jan-2003Carvedilol: Relação Entre a Actividade Antioxidante e Inibição da Transição de Permeabilidade MitocondrialOliveira, Paulo J. ; Esteves, Telma ; Rolo, Anabela P. ; Monteiro, Pedro ; Gonçalves, Lino ; Palmeira, Carlos M. ; Moreno, António J. articleopenAccess
2314-Oct-2023Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate ModelPereira, Susana P. ; Diniz, Mariana S. ; Tavares, Ludgero C. ; Cunha-Oliveira, Teresa ; Li, Cun; Cox, Laura A ; Nijland, Mark J. ; Nathanielsz, Peter W. ; Oliveira, Paulo J. articleopenAccess
242003Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilolRolo, Anabela P. ; Oliveira, Paulo J. ; Moreno, António J. ; Palmeira, Carlos M. articleopenAccess
252001Chenodeoxycholate Is a Potent Inducer of the Permeability Transition Pore in Rat Liver MitochondriaRolo, Anabela ; Oliveira, Paulo ; Moreno, António ; Palmeira, Carlos articleopenAccess
2626-Feb-2015Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System - Impact of Different Doxorubicin Treatment RegimensCarvalho, Filipa doctoralThesisembargoedAccess
2713-Oct-2008Complex Formation between Heptakis(2,6-di-O-methyl)-β-cyclodextrin and Cyclopentadienyl Molybdenum(II) Dicarbonyl Complexes: Structural Studies and Cytotoxicity EvaluationsPereira, Cláudia C. L. ; Diogo, Cátia V. ; Burgeiro, Ana ; Oliveira, Paulo J. ; Marques, M. Paula M. ; Braga, Susana S. ; Paz, Filipe A. Almeida ; Pillinger, Martyn ; Gonçalves, Isabel S. articleopenAccess
28Nov-2021Corrigendum to 'A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients'. [Redox Biology 45 (2021) 102037]Deus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Teixeira, José ; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda; Raimundo, Nuno ; Oliveira, Paulo J. articleopenAccess
2929-Oct-2021Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative AnalysisFernandes, Carlos; Videira, Afonso J. C.; Veloso, Caroline D. ; Benfeito, Sofia; Soares, Pedro; Martins, João D. ; Gonçalves, Beatriz Nunes ; Duarte, José F. S.; Santos, António M. S.; Oliveira, Paulo J. ; Borges, Fernanda; Teixeira, José ; Silva, Filomena S. G. articleopenAccess
302006Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosisTeodoro, João ; Rolo, Anabela P. ; Oliveira, Paulo J. ; Palmeira, Carlos M. articleopenAccess
312001Decreased Susceptibility of Heart Mitochondria from Diabetic GK Rats to Mitochondrial Permeability Transition Induced by Calcium PhosphateOliveira, Paulo ; Rolo, Anabela ; Seiça, R. ; Palmeira, Carlos ; Santos, M. S. ; Moreno, António articleopenAccess
322022Decreasing doxorubicin-induced cardiotoxicity with Nigella sativa seed extract: Traditional medicine targeting a severe clinical problemOliveira, Paulo J. articleopenAccess
334-May-2016Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B AssaySilva, Filomena S. G. ; Starostina, Irina G. ; Ivanova, Vilena V. ; Rizvanov, Albert A. ; Oliveira, Paulo J. ; Pereira, Susana P. articleopenAccess
3428-Jul-2017Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondriaTeixeira, José ; Oliveira, Catarina; Amorim, Ricardo ; Cagide, Fernando; Garrido, Jorge ; Ribeiro, José A.; Pereira, Carlos M.; Silva, António F. M. ; Andrade, Paula B.; Oliveira, Paulo J. ; Borges, FernandaarticleopenAccess
352003Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contentsFerreira, Fernanda M. ; Seiça, Raquel ; Oliveira, Paulo J. ; Coxito, Pedro M. ; Moreno, António J. ; Palmeira, Carlos M. ; Santos, Maria S. articleopenAccess
362016Diet, Lifestyles, Family History, and Prostate Cancer Incidence in an East Algerian Patient GroupLassed, Somia; Deus, Cláudia M. ; Lourenço, Nuno ; Dahdouh, Abderrezak; Rizvanov, Albert A. ; Oliveira, Paulo J. ; Zama, DjamilaarticleopenAccess
372008Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell lineSerafim, Teresa ; Oliveira, Paulo ; Sardão, Vilma ; Perkins, Ed ; Parke, Donna ; Holy, Jon articleopenAccess
38Jan-2011Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicologyMota, Paula C. ; Cordeiro, Marília ; Pereira, Susana P. ; Oliveira, Paulo J. ; Moreno, António J. ; Ramalho-Santos, João articleopenAccess
392014Differential immuno-reactivity to genomic DNA, RNA and mitochondrial DNA is associated with auto-immunityIvanova, Vilena V ; Khaiboullina, Svetlana F; Cherenkova, Ekaterina E; Martynova, Ekaterina V; Nevzorova, Tatiana A; Kunst, Michail A; Sibgatullin, Timur B; Maksudova, Adelia N; Oliveira, Paulo J. ; Lombardi, Vincent C; Palotas, Andras ; Rizvanov, Albert A articleopenAccess
402011Dimethylaminopyridine derivatives of lupane triterpenoids acting as mitochondrial-directed agents on breast cancer cellsBernardo, Telma Sofia Correia masterThesisopenAccess
412013Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transitionBernardo, Telma C. ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Holy, Jon ; Krasutsky, Dmytro ; Kolomitsyna, Oksana ; Krasutsky, Pavel ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
422013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, J. ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
43Dec-2018Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acidTeixeira, José ; Oliveira, Catarina; Cagide, Fernando; Amorim, Ricardo ; Garrido, Jorge ; Borges, Fernanda; Oliveira, Paulo J. articleopenAccess
442008Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damageCardoso, Susana; Santos, Renato X. ; Carvalho, Cristina ; Correia, Sónia ; Pereira, Gonçalo C. ; Pereira, Susana S. ; Oliveira, Paulo J. ; Santos, Maria S. ; Proença, Teresa ; Moreira, Paula I. articleopenAccess
4525-Nov-2019Doxorubicin persistently rewires cardiac circadian homeostasis in miceFerreira, Luciana L ; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição ; Cunha-Oliveira, Teresa ; Sassone-Corsi, Paolo; Oliveira, Paulo J. articleembargoedAccess
462018Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytesCunha-Oliveira, Teresa ; Ferreira, Luciana L ; Coelho, Ana Raquel ; Deus, Cláudia M ; Oliveira, Paulo J articleopenAccess
4711-Mar-2013Doxorubicin-Induced Cardiotoxicity: From Bioenergetic Failure and Cell Death to CardiomyopathyCarvalho, Filipa S. ; Burgeiro, Ana ; Garcia, Rita ; Moreno, Antonio J. ; Carvalho, Rui A. ; Oliveira, Paulo J. articleopenAccess
483-May-2020Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healingPonte, Susana; Carvalho, Lara; Gagliardi, Maria; Campos, Isabel; Oliveira, Paulo J. ; Jacinto, António articleopenAccess
4922-Mar-2022Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo ProductionSantos, João Campos; Marques, Carla Cruz; Baptista, Maria Conceição; Pimenta, Jorge ; Teixeira, José ; Montezinho, Liliana ; Cagide, Fernando; Borges, Fernanda; Oliveira, Paulo J. ; Pereira, Rosa M. L. N.articleopenAccess
502000Effects of Carvedilol on Isolated Heart Mitochondria: Evidence for a Protonophoretic MechanismOliveira, Paulo J. ; Marques, M. Paula M. ; Carvalho, Luís A. E. Batista de ; Moreno, A. J. M. articleopenAccess
512006Effects of endurance training and acute doxorubicin treatment on rat heart mitochondrial alterations induced by in vitro anoxia-reoxygenationAscensão, António ; Ferreira, Rita ; Oliveira, Paulo ; Magalhães, José articleopenAccess
521-Jun-2015Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestationPereira, Susana P. ; Oliveira, Paulo J. ; Tavares, Ludgero C. ; Moreno, António J. ; Cox, Laura A. ; Nathanielsz, Peter W. ; Nijland, Mark J. articleopenAccess
532006Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenationAscensão, António ; Magalhães, José ; Soares, José M.C. ; Ferreira, Rita ; Neuparth, Maria J. ; Marques, Franklim ; Oliveira, Paulo J. ; Duarte, José A. articleopenAccess
542003Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic ratsOliveira, Paulo J. ; Seiça, Raquel ; Coxito, Pedro M. ; Rolo, Anabela P. ; Palmeira, Carlos M. ; Santos, Maria S. ; Moreno, António J. M. articleopenAccess
5516-Oct-2006Esterification Prevents Induction of the Mitochondrial Permeability Transition by N-Acetyl Perfluorooctane SulfonamidesO'Brien, Timothy M. ; Carlson, Robert M. ; Oliveira, Paulo J. ; Wallace, Kendall B. articleopenAccess
5610-Mar-2022Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational StatisticsSimões, Rui F. ; Oliveira, Paulo J. ; Oliveira, Teresa Cunha ; Pereira, Francisco B. articleopenAccess
57Sep-2014Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitisGonçalves, Inês O. ; Maciel, Elisabete ; Passos, Emanuel ; Torrella, Joan R. ; Rizo, David ; Viscor, Ginés ; Rocha-Rodrigues, Silvia ; Santos-Alves, Estela ; Domingues, Maria R. ; Oliveira, Paulo J. ; Ascensão, António ; Magalhães, José articleopenAccess
5819-May-2021Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 CellsAmorim, Ricardo ; Simões, Inês C. M.; Veloso, Caroline ; Carvalho, Adriana ; Simões, Rui F. ; Pereira, Francisco B. ; Thiel, Theresa; Normann, Andrea; Morais, Catarina M. ; Jurado, Maria Amália da Silva ; Wieckowski, Mariusz R. ; Teixeira, José ; Oliveira, Paulo J. articleopenAccess
59May-2018Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cellsTeixeira, José ; Basit, Farhan; Swarts, Herman G.; Forkink, Marleen; Oliveira, Paulo J. ; Willems, Peter H. G. M.; Koopman, Werner J. H. articleopenAccess
6017-Sep-2018Fetal Liver Mitochondria Alterations in an Ovine Model of Maternal ObesityCardoso, Inês Maria Nogueira masterThesisclosedAccess
6123-Feb-2021Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative DiseasesChavarria, Daniel ; Da Silva, Ophelie; Benfeito, Sofia; Barreiro, Sandra; Garrido, Jorge ; Cagide, Fernando; Soares, Pedro; Remião, Fernando ; Brazzolotto, Xavier; Nachon, Florian; Oliveira, Paulo J. ; Dias, José; Borges, FernandaarticleopenAccess
6214-Apr-2023From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted MitochondriaAmorim, Ricardo ; Magalhães, Carina C. ; Borges, Fernanda; Oliveira, Paulo J. ; Teixeira, José articleopenAccess
632015Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like PhenotypeBranco, Ana F. ; Pereira, Susana P. ; Gonzalez, Susana ; Gusev, Oleg ; Rizvanov, Albert A. ; Oliveira, Paulo J. articleopenAccess
642016Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical ApplicationsRizvanov, Albert A. ; Persson, Jenny; Şahin, Fikrettin; Bellusci, Saverio; Oliveira, Paulo J. articleopenAccess
6515-Feb-2017Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cellsDong, Lan-Feng; Kovarova, Jaromira ; Bajzikova, Martina ; Bezawork-Geleta, Ayenachew ; Svec, David ; Endaya, Berwini ; Sachaphibulkij, Karishma; Coelho, Ana R. ; Sebkova, Natasa; Ruzickova, Anna; Tan, An S; Kluckova, Katarina ; Judasova, Kristyna ; Zamecnikova, Katerina; Rychtarcikova, Zuzana; Gopalan, Vinod; Andera, Ladislav; Sobol, Margarita ; Yan, Bing; Pattnaik, Bijay; Bhatraju, Naveen; Truksa, Jaroslav ; Stopka, Pavel; Hozak, Pavel ; Lam, Alfred K.; Sedlacek, Radislav; Oliveira, Paulo J. ; Kubista, Mikael ; Agrawal, Anurag; Dvorakova-Hortova, Katerina ; Rohlena, Jakub ; Berridge, Michael V. ; Neuzil, Jiri articleopenAccess
662018Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase InhibitorsOliveira, Catarina; Cagide, Fernando; Teixeira, José ; Amorim, Ricardo ; Sequeira, Lisa; Mesiti, Francesco; Silva, Tiago ; Garrido, Jorge ; Remião, Fernando ; Vilar, Santiago; Uriarte, Eugenio ; Oliveira, Paulo J. ; Borges, FernandaarticleopenAccess
6721-May-2013Idiosyncrasy of drug induced mitochondrial liabilities : from mitochondrial DNA single nucleotide polymorphisms to mitochondrial sirtuinsPereira, Cláudia Sofia Viriato Alves doctoralThesisopenAccess
682012Impact of H9c2 Cardiomyoblast Differentiation on Isoproterenol Toxicity: Different Modulation of Signaling PathwaysBranco, Ana Filipa Roque doctoralThesisopenAccess
69Dec-2002Impacto do Carvedilol sobre o Dano Mitocondrial Induzido por Hipoxantina/Xantina Oxidase - Que Papel na Isquemia e Reperfusão do Miocárdio?Oliveira, Paulo J. ; Rolo, Anabela P. ; Monteiro, Pedro ; Gonçalves, Lino ; Palmeira, Carlos M. ; Moreno, António J. articleopenAccess
702-Dec-2013Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell PluripotencySandro, L. Pereira ; Grãos, Mário ; Rodrigues, Ana Sofia ; Anjo, Sandra I. ; Carvalho, Rui A. ; Oliveira, Paulo J. ; Arenas, Ernest ; Ramalho-Santos, João articleopenAccess
712008Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitroO'Brien, Timothy M. ; Oliveira, Paulo J. ; Wallace, Kendall B. articleopenAccess
722001Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition poreOliveira, Paulo J. ; Coxito, Pedro M. ; Rolo, Anabela P. ; Santos, Dario L. ; Palmeira, Carlos M. ; Moreno, António J. M. articleopenAccess
732-Dec-2019Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic AnaloguesChavarria, Daniel ; Fernandes, Carlos; Aguiar, Brandon; Silva, Tiago ; Garrido, Jorge ; Remião, Fernando ; Oliveira, Paulo J. ; Uriarte, Eugenio ; Borges, FernandaarticleopenAccess
74Jan-2009Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety?Pereira, Cláudia V. ; Moreira, Ana C. ; Pereira, Susana P. ; Machado, Nuno G. ; Carvalho, Filipa S. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
75Aug-2016Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicitySilva, Ana Marta ; Barbosa, Inês A. ; Seabra, Cátia ; Beltrão, Nuno ; Santos, Raquel ; Vega-Naredo, Ignacio ; Oliveira, Paulo ; Cunha-Oliveira, Teresa articleopenAccess
762018ITERATED FAILURE RATE MONOTONICITY AND ORDERING RELATIONS WITHIN GAMMA AND WEIBULL DISTRIBUTIONSArab, Idir ; Oliveira, Paulo articleopenAccess
7721-Jan-2013A lipidomic approach to hepatic mitochondrial function and toxicology : role of diet induced modificationsMonteiro, João Pedro Santos Prata doctoralThesisopenAccess
782011Lipophilic Caffeic and Ferulic Acid Derivatives Presenting Cytotoxicity against Human Breast Cancer CellsSerafim, Teresa L. ; Carvalho, Filipa S. ; Marques, Maria P. M. ; Calheiros, Rita ; Silva, Tiago ; Garrido, Jorge ; Milhazes, Nuno ; Borges, Fernanda ; Roleira, Fernanda ; Silva, Elisiário T. ; Holy, Jon ; Oliveira, Paulo J. articleopenAccess
793-Jul-2008Mechanisms of Berberine (Natural Yellow 18)–Induced Mitochondrial Dysfunction: Interaction with the Adenine Nucleotide TranslocatorPereira, Cláudia V. ; Machado, Nuno G. ; Oliveira, Paulo J. articleopenAccess
8010-Jul-2015Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cellsLoureiro, Rute; Magalhães-Novais, Sílvia ; Mesquita, Katia A. ; Baldeiras, Inês ; Sousa, Isabel S. ; Tavares, Ludgero C. ; Barbosa, Inês A. ; Oliveira, Paulo J. ; Vega-Naredo, Ignacio articleopenAccess
811-Jul-2018Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative CapacityPereira, Susana P. ; Deus, Cláudia M. ; Serafim, Teresa L. ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. articleopenAccess
821-Apr-2021Metabolic Remodeling and Quality Control Mechanisms in Parkinson's DiseaseDeus, Cláudia Maria Carrudo de doctoralThesisembargoedAccess
8312-Sep-2013A Metabolic Switch for Cell DifferentiationPereira, Sandro Lino Cardoso doctoralThesisopenAccess
842012Metodologia de estimativa da idade à morte pela clavícula :uma abordagem BayesianaVicente, Ricardo Filipe Mendes Belo masterThesisopenAccess
8521-Apr-2022Mitobullet: antioxidant targeting of mitochondria to prevent nonalcoholic fatty liver disease-induced oxidative stressAmorim, Ricardo Fernando SantosdoctoralThesisembargoedAccess
8616-Dec-2011Mitochondria and Cancer: Opening Pandora's BoxSerafim, Teresa Laura Mendes doctoralThesisopenAccess
87Mar-2022Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationshipKarkucinska-Wieckowska, Agnieszka; Simoes, Ines C M; Kalinowski, Piotr; Lebiedzinska-Arciszewska, Magdalena; Zieniewicz, Krzysztof; Milkiewicz, Piotr; Górska-Ponikowska, Magdalena; Pinton, Paolo; Malik, Afshan N; Krawczyk, Marcin; Oliveira, Paulo J. ; Wieckowski, Mariusz R. articleopenAccess
882015Mitochondria-directed antioxidants as anticancer agentsSantos, Katia Queirós Fernandes dos masterThesisopenAccess
89Dec-2014Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblastsMoreira, Ana C. ; Branco, Ana F. ; Sampaio, Susana F. ; Cunha-Oliveira, Teresa ; Martins, Tatiana R. ; Holy, Jon ; Oliveira, Paulo J. ; Sardão, Vilma A. articleopenAccess
902019A Mitochondrial Approach to Cardiovascular Risk and DiseaseVeloso, Caroline D. ; Belew, Getachew D.; Ferreira, Luciana L. ; Grilo, Luís F. ; Jones, John Griffith ; Portincasa, Piero; Sardão, Vilma A. ; Oliveira, Paulo J. articleembargoedAccess
9130-Apr-2009Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)--A model for endangered speciesMota, Paula ; Amaral, Sandra ; Martins, Luís ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
92Nov-2013Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: Differential activation of stress and survival pathwaysBranco, Ana F. ; Sampaio, Susana F. ; Wieckowski, Mariusz R. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
932013Mitochondrial membrane lipid remodeling in pathophysiology: A new target for diet and therapeutic interventionsMonteiro, João P. ; Oliveira, Paulo J. ; Jurado, A. S. otheropenAccess
942020Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defectsDeus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Pereira, Francisco B. ; Raimundo, Nuno Filipe Viegas das Neves ; Oliveira, Paulo J. articleembargoedAccess
95Nov-2007Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractionsPereira, Gonçalo C. ; Branco, Ana F. ; Matos, Júlio A. C. ; Pereira, Sandro L. ; Parke, Donna ; Perkins, Edward L. ; Serafim, Teresa L. ; Sardão, Vilma A. ; Santos, Maria S. ; Moreno, Antonio J. M. ; Holy, Jon ; Oliveira, Paulo J. articleopenAccess
962012Mitochondrionopathy phenotype in doxorubicin-treated Wistar rats depends on treatment protocol and is cardiac-specificPereira, Gonçalo C. ; Pereira, Susana P. ; Pereira, Claudia V. ; Lumini, José A. ; Magalhães, José ; Ascensão, António ; Santos, Maria S. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
9711-Oct-2019Mitochondriotropic Antioxidants Based on Dietary Phenolic Acids as Modulators of Oxidative Stress on Skin FibroblastsVeloso, Caroline Delgado masterThesisembargoedAccess
9823-Mar-2020Molecular mechanism of horizontal mitochondrial transfer from stromal cells to cancer cells with damaged mitochondrial DNACoelho, Ana Raquel LigeirodoctoralThesisembargoedAccess
992008Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targetsSardão, Vilma ; Oliveira, Paulo ; Holy, Jon ; Oliveira, Catarina ; Wallace, Kendall articleopenAccess
10020-Jul-2021Neuronal mitochondrial metabolism and dynamic profiling under physiological and pathological conditions using biological-based machine learning approachesSimões, Rui Fernando Vieira Lisboa Matias doctoralThesisembargoedAccess
1011-Nov-2014New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell deathSerafim, Teresa L. ; Carvalho, Filipa S. ; Bernardo, Telma C. ; Pereira, Gonçalo C. ; Perkins, Edward ; Holy, Jon ; Krasutsky, Dmytro A. ; Kolomitsyna, Oksana N. ; Krasutsky, Pavel A. ; Oliveira, Paulo J. articleopenAccess
1022020Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological InterventionCunha-Oliveira, Teresa ; Montezinho, Liliana ; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J. ; Silva, Filomena S. G. articleopenAccess
1032009Parabens in male infertility--Is there a mitochondrial connection?Tavares, Renata S. ; Martins, Fátima C. ; Oliveira, Paulo J. ; Ramalho-Santos, João ; Peixoto, Francisco P. articleopenAccess
10426-Jun-2019Pathophysiology of Doxorubicin Cardiotoxicity: From Mitochondrial Homeostasis to Biological ClocksFerreira, Luciana Carolina LopesdoctoralThesisembargoedAccess
1052015Pathophysiology of persistent doxorubicin cardiotoxicity : metabolic landscaping of the epigenomeFerreira, André masterThesisopenAccess
10616-Mar-2016Programming of fetal cardio-renal mitochondria by maternal nutritionPereira, Susana Patrícia da Silva doctoralThesisembargoedAccess
1072014Protection provided by phytoestrogens against cardiac lipotoxicity induced by palmitic acidCouto, Renata Lopes Familiar masterThesisopenAccess
1082001Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition poreRolo, Anabela P. ; Oliveira, Paulo J. ; Moreno, António J. M. ; Palmeira, Carlos M. articleopenAccess
1092017Protective Effect of Green Tea (Camellia sinensis (L.) Kuntze) against Prostate Cancer: From In Vitro Data to Algerian PatientsLassed, Somia; Deus, Cláudia M. ; Djebbari, Radja; Zama, Djamila; Oliveira, Paulo J. ; Rizvanov, Albert A. ; Dahdouh, Abderrezak; Benayache, Fadila; Benayache, SamirarticleopenAccess
1102006Pt(II) vs Pd(II) Polyamine Complexes as New Anticancer Drugs: A Structure- Activity StudyFiuza, S. ; Amado, A. ; Oliveira, Paulo ; Sardão, Vilma ; Carvalho, L. de ; Marques, M. articleopenAccess
111May-2020Publicly stressing the role of mitochondria in NAFLD with(in) a sports eventAlemany-Pagès, Mireia; Tavares, Rui Miguel dos Santos ; Varela Amaral, Sara; Barros-Viegas, Ana Teresa ; Oliveira, Paulo J. ; Santos, João Ramalho de Sousa ; Azul, Anabela Marisa de Jesus Rodrigues articleembargoedAccess
112Oct-2013Rapeseed oil-rich diet alters in vitro menadione and nimesulide hepatic mitochondrial toxicityMonteiro, João P. ; Silva, Ana M. ; Jurado, Amália S. ; Oliveira, Paulo J. articleopenAccess
1135-Feb-2019Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer CellsBajzikova, Martina ; Kovarova, Jaromira ; Coelho, Ana R. ; Boukalova, Stepana ; Oh, Sehyun ; Rohlenova, Katerina ; Svec, David ; Hubackova, Sona ; Endaya, Berwini ; Judasova, Kristyna ; Bezawork-Geleta, Ayenachew ; Kluckova, Katarina ; Chatre, Laurent ; Zobalova, Renata ; Novakova, Anna ; Vanova, Katerina ; Ezrova, Zuzana ; Maghzal, Ghassan J ; Magalhaes Novais, Silvia ; Olsinova, Marie ; Krobova, Linda ; An, Yong Jin ; Davidova, Eliska ; Nahacka, Zuzana ; Sobol, Margarita ; Cunha-Oliveira, Teresa ; Sandoval-Acuña, Cristian ; Strnad, Hynek ; Zhang, Tongchuan ; Huynh, Thanh ; Serafim, Teresa L. ; Hozak, Pavel ; Sardão, Vilma A. ; Koopman, Werner J H ; Ricchetti, Miria ; Oliveira, Paulo J ; Kolar, Frantisek ; Kubista, Mikael ; Truksa, Jaroslav ; Dvorakova-Hortova, Katerina ; Pacak, Karel ; Gurlich, Robert ; Stocker, Roland ; Zhou, Yaoqi ; Berridge, Michael V ; Park, Sunghyouk ; Dong, Lanfeng ; Rohlena, Jakub ; Neuzil, Jiri articleembargoedAccess
1142012Role of p66shc signaling on doxorubicin-induced cardiac mitochondrial dysfunctionSampaio, Susana Filipa Pereira masterThesisopenAccess
1152014Role of Sirtuin 3 on Doxorubicin-induced Toxicity on H9c2 CardiomyoblastsCoelho, Ana Raquel Ligeiro masterThesisopenAccess
1162008Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--Nuclear vs. mitochondrial effectsSerafim, Teresa L. ; Matos, Júlio A. C. ; Sardão, Vilma A. ; Pereira, Gonçalo C. ; Branco, Ana F. ; Pereira, Sandro L. ; Parke, Donna ; Perkins, Edward L. ; Moreno, António J. M. ; Holy, Jon ; Oliveira, Paulo J. articleopenAccess
11714-May-2021Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reductionPereira, Susana P. ; Tavares, Ludgero C. ; Duarte, Ana I. ; Baldeiras, Inês ; Cunha-Oliveira, Teresa ; Martins, João D. ; Santos, Maria S. ; Maloyan, Alina; Moreno, Antonio J. ; Cox, Laura A. ; Li, Cun; Nathanielsz, Peter W. ; Nijland, Mark J. ; Oliveira, Paulo J. articleembargoedAccess
118Feb-2019Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblastsFerreira, Luciana L. ; Cunha-Oliveira, Teresa ; Veloso, Caroline D. ; Costa, Cláudio F. ; Wallace, Kendall B. ; Oliveira, Paulo J. articleembargoedAccess
11929-Jul-2019Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrateJarak, Ivana ; Barosa, Cristina ; Martins, Fátima O. ; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, João; Viegas, Ivan ; Teixeira, José; Oliveira, Paulo J. ; Jones, John Griffith articleembargoedAccess
1205-Dec-2010Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lungMachado, Nuno G. ; Baldeiras, Inês ; Pereira, Gonçalo C. ; Pereira, Susana P. ; Oliveira, Paulo J. articleopenAccess
1211-Jan-2014Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(cyclopentadienyl)molybdenum Complexes and Cyclodextrin Inclusion CompoundsBraga, Susana S. ; Mokal, Vijaya ; Paz, Filipe A. Almeida ; Pillinger, Martyn ; Branco, Ana F. ; Sardão, Vilma A. ; Diogo, Cátia V. ; Oliveira, Paulo J. ; Marques, Maria P. M. ; Romão, Carlos C. ; Gonçalves, Isabel S. articleopenAccess
122Feb-2019Targeting mitochondria to oppose the progression of nonalcoholic fatty liver diseaseGrattagliano, Ignazio; Montezinho, Liliana P. ; Oliveira, Paulo J. ; Frühbeck, Gema; Gómez-Ambrosi, Javier; Montecucco, Fabrizio; Carbone, Federico; Wieckowski, Mariusz R. ; Wang, David Q-H; Portincasa, PieroarticleembargoedAccess
1232008Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leakAmaral, Sandra ; Mota, Paula ; Rodrigues, Ana Sofia ; Martins, Luís ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
1242009Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic ratsAmaral, Sandra ; Mota, Paula C. ; Lacerda, Beatriz ; Alves, Marco ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
12531-Oct-2023The H9c2(2-1) cell-based sulforhodamine B assay is a non-animal alternative to evaluate municipal wastewater quality over timeRodrigues, Elsa T. ; Pereira, Eduarda ; Oliveira, Paulo J. ; Pardal, Miguel Ângelo articleopenAccess
1262017The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease ProgressionVecchione, Giulia; Grasselli, Elena; Cioffi, Federica; Baldini, Francesca; Oliveira, Paulo J. ; Sardão, Vilma A. ; Cortese, Katia; Lanni, Antonia; Voci, Adriana; Portincasa, Piero ; Vergani, LauraarticleopenAccess
12714-Jan-2022The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to TherapeuticsMelim, Catarina ; Lauro, Maria R.; Pires, Isabel M.; Oliveira, Paulo J. ; Cabral, Célia articleopenAccess
12814-Mar-2014TRAP1 regulation of mitochondrial homeostasis and cellular quality controlBarbosa, Inês Biscaia de Andrade doctoralThesisembargoedAccess
1292007Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterizationMoreno, António J. ; Oliveira, Paulo J. ; Nova, Carlos D. ; Álvaro, Ana R. ; Moreira, Renata A. ; Santos, Sandra M. D. ; Macedo, Tice articleopenAccess
13029-Jul-2015Unraveling cancer metabolism through flux analysis and metabolic engineeringTavares, Ludgero Canário doctoralThesisopenAccess
13128-Feb-2020Urine-Derived Stem Cells: Applications in Regenerative and Predictive MedicineBento, Guida ; Shafigullina, Aygul K.; Rizvanov, Albert A. ; Sardão, Vilma A. ; Macedo, Maria Paula ; Oliveira, Paulo J. articleopenAccess
1322007Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell deathSardão, Vilma A. ; Oliveira, Paulo J. ; Holy, Jon ; Oliveira, Catarina R. ; Wallace, Kendall B. articleopenAccess
1332004Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki ratsOliveira, Paulo J. ; Seiça, Raquel ; Santos, Dario L. ; Rolo, Anabela P. ; Sardão, Vilma A. ; Ferreira, Fernanda M. L. ; Palmeira, Carlos M. ; Santos, Maria S. ; Moreno, António J. M. articleopenAccess
13415-Oct-2020Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic ResponseSimoes, Ines C M; Karkucinska-Wieckowska, Agnieszka; Janikiewicz, Justyna; Szymanska, Sylwia; Pronicki, Maciej; Dobrzyn, Pawel; Dabrowski, Michal; Dobrzyn, Agnieszka; Oliveira, Paulo J. ; Zischka, Hans; Potes, Yaiza; Wieckowski, Mariusz R. articleopenAccess
1352014β-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?Branco, Ana F. ; Moreira, Ana C. ; Cunha-Oliveira, Teresa ; Couto, Renata ; Sardão, Vilma A. ; Rizvanov, Albert A. ; Palotas, Andras ; Oliveira, Paulo J. articleopenAccess

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