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Name
Moreira, Paula I.
 
Variants
Moreira, P. I.
Moreira, Paula Isabel
 
 
Email
pimoreira@fmed.uc.pt
 
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Status
UC Researcher
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Publications

Results 1-56 of 56 (Search time: 0.001 seconds).

Issue DateTitleAuthor(s)TypeAccess
12001Amyloid ß-Peptide Promotes Permeability Transition Pore in Brain MitochondriaMoreira, Paula ; Santos, Maria ; Moreno, António ; Oliveira, Catarina articleopenAccess
220-Aug-2020Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly CohortGerardo, Bianca ; Pinto, Marina Cabral ; Nogueira, Joana ; Pinto, Paula ; Almeida, Agostinho ; Pinto, Edgar; Marinho-Reis, Paula; Diniz, Luísa; Moreira, Paula I. ; Simões, Mário ; Freitas, Sandra articleopenAccess
32014Brain endothelial cells protection by pinacidil preconditioning in an okadaic acid-induced Alzheimer’s disease model: role of mitoKATP channels, ROS and HIF-1αSimões, Rui Fernando Vieira Lisboa Matias masterThesisopenAccess
42007Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetesMoreira, Paula I. ; Santos, Maria S. ; Seiça, Raquel ; Oliveira, Catarina R. articleopenAccess
52005Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifenMoreira, Paula I. ; Custódio, José B. ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
62008Brain oxidative stress in a triple-transgenic mouse model of Alzheimer diseaseResende, Rosa ; Moreira, Paula Isabel ; Proença, Teresa ; Deshpande, Atul ; Busciglio, Jorge ; Pereira, Cláudia ; Oliveira, Catarina Resende articleopenAccess
72005Ciprofloxacin Does Not Exert Nephrotoxicity in RatsBaykal, Asli ; Sarigül, Figen ; Süleymanlar, Gültekin ; Moreira, Paula I. ; Perry, George ; Smith, Mark A. ; Alicigüzel, Yakup articleopenAccess
81-Apr-2020Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 InhibitorsCoimbra, Judite R. M. ; Baptista, Salete ; Dinis, Teresa ; Silva, Maria M. C. ; Moreira, Paula I. ; Santos, Armanda Emanuela Castro e ; Salvador, Jorge A. R. articleopenAccess
92006Compensatory responses induced by oxidative stress in Alzheimer diseaseMoreira, Paula I. ; Zhu, Xiongwei ; Liu, Quan ; Honda, Kazuhiro; Siedlak, Sandra L; Harris, Peggy L. R. ; Smith, Mark A. ; Perry, George articleopenAccess
1022-Aug-2023Current Advances in Mitochondrial Targeted Interventions in Alzheimer's DiseaseSousa, Tiago ; Moreira, Paula I. ; Cardoso, Susana articleopenAccess
112008Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damageCardoso, Susana; Santos, Renato X. ; Carvalho, Cristina ; Correia, Sónia ; Pereira, Gonçalo C. ; Pereira, Susana S. ; Oliveira, Paulo J. ; Santos, Maria S. ; Proença, Teresa ; Moreira, Paula I. articleopenAccess
1212-Jun-2018Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's DiseaseDuarte, Ana I. ; Sjögren, Marie; Santos, Maria S. ; Oliveira, Catarina R. ; Moreira, Paula I. ; Björkqvist, MariaarticleopenAccess
13Jan-2013Efeitos do metilglioxal e da piridoxamina na bioenergética e no estado redox de mitocôndrias de cérebro de ratoMarinho, Ricardo Cleto de Sousa masterThesisopenAccess
142011Effect of age and chronic hypoxia on oxidative status, mitochondria and apoptosis in rat liverCandeias, Emanuel Monteiro masterThesisopenAccess
152002Effect of amyloid beta-peptide on permeability transition pore: A comparative studyMoreira, Paula I. ; Santos, Maria S. ; Moreno, António ; Rego, A. Cristina ; Oliveira, Catarina articleopenAccess
162015Effects of vitamin D deficient and high-fat diets in the diabetic brain: focus on insulin signalingLoureiro, Guilherme Alvarinhas de Assis masterThesisopenAccess
172007Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female ratsMoreira, Paula I. ; Custódio, José B.A. ; Nunes, Elsa ; Moreno, António ; Seiça, Raquel ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
1816-Jul-2013Exploring the role of mithocondria and uncopling proteins in hypoglycemia and/or hypoglycemia-induced brain damageCardoso, Susana Maria Batista Tieres Tomé doctoralThesisopenAccess
192012Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?Mondragón-Rodríguez, Siddhartha; Perry, George; Zhu, Xiongwei ; Moreira, Paula I. ; Williams, SylvainarticleopenAccess
202018Highlights in BACE1 Inhibitors for Alzheimer's Disease TreatmentCoimbra, Judite R. M. ; Marques, Daniela F. F. ; Baptista, Salete J. ; Pereira, Cláudia Fragão ; Moreira, Paula I. ; Dinis, Teresa C. P. ; Santos, Armanda E. ; Salvador, Jorge A. R. articleopenAccess
212017Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elementsPinto, Marina Cabral ; Reis, Ana P. ; Almeida, Agostinho ; Ordens, Carlos M. ; Silva, M. ; Freitas, Sandra ; Simões, Mário Rodrigues ; Moreira, Paula I. ; Dinis, P. A. ; Diniz, M. L. ; Silva, E. A. Ferreira da ; Melo, M. T. Condesso de articleopenAccess
222004Hydroxytamoxifen protects against oxidative stress in brain mitochondriaMoreira, Paula I. ; Custódio, José B. ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
236-Feb-2021IGF1R Deficiency Modulates Brain Signaling Pathways and Disturbs Mitochondria and Redox HomeostasisCardoso, Susana ; López, Icíar P.; Piñeiro-Hermida, Sergio; Pichel, José G.; Moreira, Paula I. articleopenAccess
24Jun-2003Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposureMoreira, Paula I. ; Santos, Maria S. ; Moreno, António M. ; Seiça, Raquel ; Oliveira, Catarina R. articleopenAccess
252007Indices of Metabolic Dysfunction and Oxidative StressCasadesus, Gemma ; Moreira, Paula ; Nunomura, Akihiko ; Siedlak, Sandra ; Bligh-Glover, William ; Balraj, Elizabeth ; Petot, Grace ; Smith, Mark ; Perry, George articleopenAccess
2623-Nov-2009Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic TargetsCardoso, Susana ; Santos, Renato ; Correia, Sonia ; Carvalho, Cristina ; Zhu, Xiongwei ; Lee, Hyoung-Gon ; Casadesus, Gemma ; Smith, Mark A. ; Perry, George ; Moreira, Paula I. reviewopenAccess
272009Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic TargetsCardoso, Susana; Santos, Renato; Correia, Sonia; Carvalho, Cristina; Zhu, Xiongwei ; Lee, Hyoung-gon ; Casadesus, Gemma ; Smith, Mark A. ; Perry, George; Moreira, Paula I. articleopenAccess
282014Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease - How Anti-Diabetics Could be a Solution for DementiaSebastião, Inês ; Candeias, Emanuel ; Santos, Maria S. ; Oliveira, Catarina R. de ; Moreira, Paula I. ; Duarte, Ana I. articleopenAccess
292012Insulin in central nervous system: more than just a peripheral hormoneDuarte, Ana I. ; Moreira, Paula I. ; Oliveira, C. R. articleopenAccess
305-Jan-2021Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's DiseaseCorreia, Sónia C. ; Machado, Nuno J. ; Alves, Marco G; Oliveira, Pedro F. ; Moreira, Paula I. articleopenAccess
312007Iron: The Redox-active Center of Oxidative Stress in Alzheimer DiseaseCastellani, Rudy ; Moreira, Paula ; Liu, Gang ; Dobson, Jon ; Perry, George ; Smith, Mark ; Zhu, Xiongwei articleopenAccess
3218-Nov-2019Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial AreaCabral Pinto, Marina M. S.; Marinho-Reis, Paula; Almeida, Agostinho ; Pinto, Edgar; Neves, Orquídia; Inácio, Manuela; Gerardo, Bianca ; Freitas, Sandra ; Simões, Mário R. ; Dinis, Pedro A. ; Diniz, Luísa; Ferreira da Silva, Eduardo; Moreira, Paula I. articleopenAccess
33Sep-2007Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblastsMoreira, Paula I. ; Harris, Peggy L. R. ; Zhu, Xiongwei ; Santos, Maria S. ; Oliveira, Catarina R. ; Smith, Mark A. ; Perry, George articleopenAccess
342-Apr-2021Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's diseaseFerreira, Hugo ; Martins, João ; Moreira, Paula I. ; Ambrósio, António Francisco ; Castelo-Branco, Miguel ; Serranho, Pedro ; Bernardes, Rui articleopenAccess
352008Metformin promotes isolated rat liver mitochondria impairmentCarvalho, Cristina ; Correia, Sónia ; Santos, Maria ; Seiça, Raquel ; Oliveira, Catarina ; Moreira, Paula articleopenAccess
3616-Jul-2007Mitochondrial dysfunction in Alzheimer's disease and diabetes : effect of compounds with antioxidant propertiesMoreira, Paula Isabel da Silva doctoralThesisembargoedAccess
3712-Nov-2012Mitochondrial Preconditioning-Triggered Brain Tolerance. Implications for Alzheimer's Disease and DiabetesCorreia, Sónia Catarina de Sousa doctoralThesisopenAccess
382010Mitochondrial preconditioning: a potential neuroprotective strategyCorreia, Sónia C. ; Carvalho, Cristina ; Cardoso, Susana ; Santos, Renato X. ; Santos, Maria S. ; Oliveira, C. R. ; Perry, George; Zhu, Xiongwei ; Smith, Mark A. ; Moreira, Paula I. articleopenAccess
3917-Jul-2017Neuronal energy status and Alzheimer's disease: searching for a connection.Verde, Diogo Miguel Matos Vila masterThesisclosedAccess
402023Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's diseaseBatista, Ana ; Guimarães, Pedro ; Martins, João ; Moreira, Paula I. ; Ambrósio, António Francisco ; Castelo-Branco, Miguel ; Serranho, Pedro ; Bernardes, Rui articleopenAccess
412008Nucleic acid oxidation in Alzheimer diseaseMoreira, Paula I. ; Nunomura, Akihiko ; Nakamura, Masao ; Takeda, Atsushi ; Shenk, Justin C. ; Aliev, Gjumrakch ; Smith, Mark A. ; Perry, George articleopenAccess
4218-Jul-2017O-GlcNAcylation represents a “sweet” route to tackle Alzheimer’s disease-related phenotypePinho, Tiffany Santos masterThesisclosedAccess
432018Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative EventsCarvalho, Cristina ; Moreira, Paula I. articleopenAccess
448-Mar-2023A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative DiseasesFernandes, Tânia ; Domingues, M. Rosário M. ; Moreira, Paula I. ; Pereira, Cláudia F. articleopenAccess
452013Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's diseaseMondragón-Rodríguez, Siddhartha; Perry, George; Zhu, Xiongwei ; Moreira, Paula I. ; Acevedo-Aquino, Mariana C; Williams, SylvainarticleopenAccess
462014Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stressRato, Luis ; Duarte, Ana I. ; Tomás, Gonçalo D. ; Santos, M. S. ; Moreira, Paula I. ; Socorro, Silvia ; Cavaco, José E. ; Alves, Marco G. ; Oliveira, Pedro F. articleopenAccess
472005Redox metals and oxidative abnormalities in human prion diseasesPetersen, Robert ; Siedlak, Sandra ; Lee, Hyoung-Gon ; Kim, Yong-Sun ; Nunomura, Akihiko ; Tagliavini, Fabrizio ; Ghetti, Bernardino ; Cras, Patrick ; Moreira, Paula ; Castellani, Rudy ; Guentchev, Marin ; Budka, Herbert ; Ironside, James ; Gambetti, Pierluigi ; Smith, Mark ; Perry, George articleopenAccess
4813-Nov-2019Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo studyChiquita, Samuel; Campos, Elisa J. ; Castelhano, João ; Ribeiro, Mário ; Sereno, José ; Moreira, Paula I. ; Castelo-Branco, Miguel ; Ambrósio, António Francisco articleopenAccess
4926-Feb-2016Role of endoplasmic reticulum stress in Alzheimer's disease-assocated neuronal and endothelial dysfunctionFernandes, Ana Isabel Plácido doctoralThesisopenAccess
50May-2008Sublethal RNA oxidation as a mechanism for neurodegenerative diseaseCastellani, Rudy J; Nunomura, Akihiko ; Rolston, Raj K; Moreira, Paula I. ; Takeda, Atsushi ; Perry, George ; Smith, Mark A. articleopenAccess
5114-Apr-2006Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failureMoreira, Paula I. ; Custódio, José ; Moreno, António ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
522005Tau phosphorylation in Alzheimer's disease: pathogen or protector?Lee, Hyoung-gon ; Perry, George ; Moreira, Paula I. ; Garrett, Matthew R. ; Liu, Quan ; Zhu, Xiongwei ; Takeda, Atsushi ; Nunomura, Akihiko ; Smith, Mark A. articleopenAccess
5323-Nov-2021The amazing anti-type 2 diabetic drugs in neurodegeneration: the impact of exendin-4, liraglutide and linagliptin in type 2 diabetes, Alzheimer disease and Parkinson diseaseCandeias, Emanuel MonteirodoctoralThesisopenAccess
5413-Jun-2013The interplay between vascular and mitochondrial abnormalities in type 2 diabetes and Alzheimer’s diseaseCarvalho, Cristina Isabel Marques Maurício de doctoralThesisopenAccess
5519-Nov-2014The involvement of mitochondrial fission, fusion and biogenesis and autophagy in the diabetic brainSantos, Renato Xavier doctoralThesisopenAccess
562013UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic ratsCardoso, Susana ; Santos, M. S. ; Moreno, A. J. M. ; Moreira, Paula I. articleopenAccess