Pereira, Susana P.

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Credit Name
Pereira, Susana P.
 
Full Name
Pereira, Susana Patrícia da Silva
 
Variants
Pereira, Susana
Pereira, Susana P.
Pereira, S. S.
Pereira, S. P.
 
 
 
Ciência ID
 
Scopus Author ID
 
Researcher ID
 
Biography
I obtained the Applied Biology Degree at University of Minho, Braga, Portugal in 2007 investigating the toxicity of the herbicides metolachlor and alachlor on bacterial model, Bacillus stearothermophilus and membrane model system of lipossomes of DPPC. These findings were published in Environmental Pollution as first author (IF 6.8,Top 5%). In 2009, I completed the Master’s in Cellular and Molecular Biology, University of Coimbra, Portugal, studying the In vivo effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on heart and liver mitochondrial bioenergetics and ATP-sensitive potassium channels publishing this work on Top 2% in Medicine/General Medicine. I obtained a Ph.D. degree at the University of Coimbra, Portugal in 2016 researching the “Programming of fetal cardio-renal mitochondria by maternal nutrition” publishing two seminal papers on Top 5% explaining the "Effects of Moderate Global Maternal Nutrient Reduction on Fetal Baboon Renal Mitochondrial Gene Expression at 0.9 Gestation” and the recently accepted “Sex dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction”. (Clinical Science, IF 5.2, Top5%, 1st author) revealing the causal relationship between nutrition during pregnancy and the development of diabetes and cardio-renal dysfunction later in life in a baboon model. In this context, I spent 24 months working at both the university of Texas Health Science Center and later at the University of Wyoming, Laramie, this international experience afforded me contact with world-class scientists and cutting-edge science. In this regard, I have contributed to a strong research collaboration with outstanding international experts such as Drs. Peter Nathanielsz and Mark Nijland (Texas Biomedical Research Institute, USA) and Dr. Stephen P. Ford (University of Wyoming, USA) who provided me with a scientific knowledge and know-how to conduct research work in this area. Recently I have being testing the practice of voluntary exercise during gestational diabetes as a means to improve mitochondrial function in the offspring, with the first manuscript recently published in Metabolism: Clinical and Experimental (IF 6.5, Top 6%). So far, I co-authored 24 full-length original articles published in peer reviewed journals, with 10 in top 10%, 7 first author, 6 second author, 2 last author, 1 first author book chapter, with 79% in Q1, >550 citations and h-index 14 (scholar). I am publishing in the best journals in my area and with the relevance and recognition of my research being mirrored in the high number of citations. I have 7 invited oral communications; 35 oral presentations; 57 poster presentations; 48 abstracts in conference proceedings and received 20 awards and honors. I prioritize knowledge dissemination, organizing 16 scientific meetings, 11 outreach science activities and attending more than 50 advanced courses. I scientific co-supervised 17 students; performed 11 teaching activities and participated in 11 scientific societies. I broaden my knowledge collaborating in >10 research team projects, with solid international collaborations and acting as an ad-hoc reviewer in four different publications including Antioxidants & Redox Signaling and The Journal of Physiology. My main research interest is cardiac diseases and mitochondrial bioenergetics in health and disease, namely I aim to clarify the role of nutritional womb environment in fetal cardiac development. My work supports that gestational programming of fetal mitochondrial fitness can be relevant for cardiac pathologies in the adult life. In summary, I am a researcher performing novel and creative science who is positively influencing the development of a field, I am also an enthusiastic of developing innovative and effective ways to engage society in science, improving science literacy and education.
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Status
UC Researcher
 

Publications

Results 1-22 of 22 (Search time: 0.05 seconds).

Issue DateTitleAuthor(s)TypeAccess
12012Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial functionMota, Paula C. ; Tavares, Renata S. ; Cordeiro, Marília ; Pereira, Susana P. ; Publicover, Stephen J. ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
2Sep-2009Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?Pereira, Susana P. ; Pereira, Gonçalo C. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
32016Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial functionPereira, Gonçalo C. ; Pereira, Susana P. ; Tavares, Ludgero C. ; Carvalho, Filipa S. ; Magalhães-Novais, Sílvia ; Barbosa, Inês A. ; Santos, Maria S. ; Bjork, James ; Moreno, António J. ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
417-Jun-2008Comparative effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: Relevance to the length of the alkoxyl chain in positions 3 and 5 of the DHP ringFernandes, Maria A. S. ; Pereira, Susana P. S. ; Jurado, Amália S. ; Custódio, José B. A. ; Santos, Maria S. ; Moreno, António J. M. ; Duburs, Gunars ; Vicente, Joaquim A. F. articleopenAccess
54-May-2016Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B AssaySilva, Filomena S. G. ; Starostina, Irina G. ; Ivanova, Vilena V. ; Rizvanov, Albert A. ; Oliveira, Paulo J. ; Pereira, Susana P. articleopenAccess
6Jan-2011Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicologyMota, Paula C. ; Cordeiro, Marília ; Pereira, Susana P. ; Oliveira, Paulo J. ; Moreno, António J. ; Ramalho-Santos, João articleopenAccess
7Sep-2013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, João ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
82013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, J. ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
92008Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damageCardoso, Susana; Santos, Renato X. ; Carvalho, Cristina ; Correia, Sónia ; Pereira, Gonçalo C. ; Pereira, Susana S. ; Oliveira, Paulo J. ; Santos, Maria S. ; Proença, Teresa ; Moreira, Paula I. articleopenAccess
101-Jun-2015Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestationPereira, Susana P. ; Oliveira, Paulo J. ; Tavares, Ludgero C. ; Moreno, António J. ; Cox, Laura A. ; Nathanielsz, Peter W. ; Nijland, Mark J. articleopenAccess
112015Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like PhenotypeBranco, Ana F. ; Pereira, Susana P. ; Gonzalez, Susana ; Gusev, Oleg ; Rizvanov, Albert A. ; Oliveira, Paulo J. articleopenAccess
1226-Feb-2020The Heart of the Question: Exercise During Gestational Diabetes, Does It Work?Rodrigues, Óscar Emanuel de MelomasterThesisembargoedAccess
13Jan-2009Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety?Pereira, Cláudia V. ; Moreira, Ana C. ; Pereira, Susana P. ; Machado, Nuno G. ; Carvalho, Filipa S. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
141-Jul-2018Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative CapacityPereira, Susana P. ; Deus, Cláudia M. ; Serafim, Teresa L. ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. articleopenAccess
158-Jun-2021A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patientsDeus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Teixeira, José; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda ; Raimundo, Nuno Filipe Viegas das Neves ; Oliveira, Paulo J. articleopenAccess
1620-Nov-2019Mitochondrial remodeling in human skin fibroblasts from sporadic PD male patients uncovers metabolic and mitochondrial bioenergetics defectsDeus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Pereira, Francisco B. ; Raimundo, Nuno Filipe Viegas das Neves ; Oliveira, Paulo J. articleembargoedAccess
172012Mitochondrionopathy phenotype in doxorubicin-treated Wistar rats depends on treatment protocol and is cardiac-specificPereira, Gonçalo C. ; Pereira, Susana P. ; Pereira, Claudia V. ; Lumini, José A. ; Magalhães, José ; Ascensão, António ; Santos, Maria S. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
1812-Sep-2019Obesity-induced hepatic changes during pregnancyGrilo, Luís Filipe FragosomasterThesisembargoedAccess
1916-Mar-2016Programming of fetal cardio-renal mitochondria by maternal nutritionPereira, Susana Patrícia da Silva doctoralThesisembargoedAccess
2014-May-2021Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reductionPereira, Susana P. ; Tavares, Ludgero C. ; Duarte, Ana I. ; Baldeiras, Inês ; Cunha-Oliveira, Teresa ; Martins, João D. ; Santos, Maria S. ; Maloyan, Alina; Moreno, Antonio J. ; Cox, Laura A. ; Li, Cun; Nathanielsz, Peter W. ; Nijland, Mark J. ; Oliveira, Paulo J. articleembargoedAccess
215-Dec-2010Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lungMachado, Nuno G. ; Baldeiras, Inês ; Pereira, Gonçalo C. ; Pereira, Susana P. ; Oliveira, Paulo J. articleopenAccess
22Dec-2009Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systemsPereira, Susana P. ; Fernandes, Maria A. S. ; Martins, João D. ; Santos, Maria S. ; Moreno, António J. M. ; Vicente, Joaquim A. F. ; Videira, Romeu A. ; Jurado, Amália S. articleopenAccess