Ramalho-Santos, João

Loading... 2 0 5 0 false
 
Credit Name
Ramalho-Santos, João
 
Full Name
Santos, João Ramalho de Sousa
 
 
 
 
Scopus Author ID
 
Researcher ID
 
Biography
João Ramalho-Santos is Professor at the Department of Life Sciences, University of Coimbra, Portugal, where he concluded his Ph.D in Cell Biology in 1997. He was a post-doctoral fellow in Reproductive Biology at Oregon Health & Science University USA (1997-2000), a Visiting Scientist at University of Pittsburgh, USA (2003-2006) and a Fulbright Fellow at University of California San Francisco, USA (2009). He currently is the Head of the Biology of Reproduction and Stem Cells Group at the Center for Neuroscience and Cell Biology at the University of Coimbra where he works on the bioenergetics and metabolism of gametes and stem cells, and on Science Communication and Bioethics issues related both to Assisted Reproduction and metabolism, aging and disease.
He is also Director of the Center for Neuroscience and Cell Biology.
He is Associate Editor of the Journals Reproduction and Human Reproduction, reviewer for over 30 journals and 6 agencies (Including FCT, Portugal, MRC, UK, and DFG, Germany). He is a former member of the National Ethics Council for the Life Sciences (CNECV)
h-Factor 47 (Google Scholar), 38 (ISI)
Citations: 8500 (Google Scholar), 5100 (ISI)
Loading... 3 0 5 0 false
Status
UC Researcher
 

Publications

Results 1-93 of 93 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
12001Acrosome components after intracytoplasmic sperm injection: the decondensation frontierRamalho-Santos, João ; Simerly, Calvin R. ; Hewitson, Laura ; Schatten, Gerald articleopenAccess
227-Jun-1997Actividade fusogénica de vírus com envelope lipídico : fusão de membranas promovida pelos vírus influenza e SendaiSantos, João Ramalho de Sousa doctoralThesisembargoedAccess
32012Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial functionMota, Paula C. ; Tavares, Renata S. ; Cordeiro, Marília ; Pereira, Susana P. ; Publicover, Stephen J. ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
47-Oct-2019Analysis of metabolic heterogeneity over cell division cycle in non-synchronized yeast a 13c based experimental-computational approachSantos, Inês Vasconcelos MirandadoctoralThesisopenAccess
512-Sep-2019Analysis of the Efficacy and Safety of Spermicides with Benzalkonium Cholride and Myristalkonium Chloride as Active PrinciplesAlfaiate, Maria Inês RodriguesmasterThesisclosedAccess
62013Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengthsAlçada-Morais, Sofia ; Sousa, Ana Paula ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, J. articleopenAccess
718-Dec-2012Approaches to Improve the Differentiation, Maturation and Biological Activity of Vascular Cells Derived from Stem CellsVazão, Helena Sofia Esmeraldo de Campos doctoralThesisopenAccess
82012Avaliação da integridade da cromatina em espermatozóides humanos : relevância clínicaSilva, Andreia Filipa Neves da masterThesisopenAccess
92012Biomarcadores em tumores das células germinativasSimões, Sónia Catarina Lopes masterThesisopenAccess
102018Bridging Health and Social Care with the Citizens – The Case of EIT Health Project “Healiqs4cities” and “Praça Vida+”, in PortugalSá-Moura, Bebiana; Couceiro, Patrícia ; Catarino, Luis ; Guardado, Diana; Brito, Maja de; Silva, Bárbara ; Tavares, Rui ; Ramalho-Santos, João ; Teixeira, Ana M. ; Rama, Luís ; Reis, Flávio ; Mota-Pinto, Anabela ; Veríssimo, Manuel ; Gonçalves, Carlos ; Cunha, António ; Malva, João O. articleopenAccess
112012Calcium mobilisation in human sperm and its effects on motilityFernandes, Leonor Cruz masterThesisopenAccess
122014A Cat Problem: Characterization of Feline Spermatogonial Stem CellsRebelo, Sara de Jesus Gomes Escada masterThesisopenAccess
132007Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markersVarum, Sandra ; Bento, Carla ; Sousa, Ana Paula M. ; Gomes-Santos, Carina S. S. ; Henriques, Paula ; Almeida-Santos, Teresa ; Teodósio, Cristina ; Paiva, Artur ; Ramalho-Santos, João articleopenAccess
1418-Jan-2016Characterization of KIR2DS1+ decidual Natural Killer cells in healthy and viral/bacterial – infected human pregnancyCrespo, Ângela Pascoal da Costa doctoralThesisopenAccess
15Mar-1993A common mechanism for influenza virus fusion activity and inactivationRamalho-Santos, João ; Nir, Shlomo ; Düzgünes, Nejat ; Carvalho, Arsélio Pato de ; Lima, Maria da Conceição Pedroso de articleopenAccess
1610-Sep-2018Comparação de parâmetros mitocondriais entre oócitos jovens e envelhecidosFernandes, Raquel Direito masterThesisclosedAccess
172006Comparison between different markers for sperm quality in the cat: Diff-Quik as a simple optical technique to assess changes in the DNA of feline epididymal spermMota, Paula C. ; Ramalho-Santos, João articleopenAccess
1822-Dec-2015Desafios na Inovação da Comunicação de Ciência em PortugalAmaral, Sara Varela doctoralThesisopenAccess
19Jan-2011Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicologyMota, Paula C. ; Cordeiro, Marília ; Pereira, Susana P. ; Oliveira, Paulo J. ; Moreno, António J. ; Ramalho-Santos, João articleopenAccess
20Sep-2013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, João ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
212013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, J. ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
225-Jan-2021Dissecting the Mechanisms Governing Skin Wound Healing Induced by an Umbilical Cord Blood-Derived ProductRodrigues, Sílvia Maria do CoutodoctoralThesisopenAccess
232009Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sperm morphology and chromatin statusSousa, Ana Paula M. ; Tavares, Renata S. ; Velez de la Calle, Juan Felipe ; Figueiredo, Helena ; Almeida, Vasco ; Almeida-Santos, Teresa ; Ramalho-Santos, João articleopenAccess
2420-Sep-2017Edible mushrooms as mediators of sustainability and human healthGomes, Cátia de Fátima Pires masterThesisopenAccess
252006Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetesAmaral, Sandra ; Moreno, António J. ; Santos, Maria Sancha ; Seiça, Raquel ; Ramalho-Santos, João articleopenAccess
262012Effects of Nicotine, Anandamide and Sildenafil Citrate in Sperm Function: The Role of the MitochondriaSousa, Maria Inês Ramalho de Almeida e masterThesisopenAccess
2717-Jun-2011Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated CounterpartsVarum, Sandra ; Rodrigues, Ana S. ; Moura, Michelle B. ; Momcilovic, Olga ; Easley, Charles A. ; Ramalho-Santos, João ; Van Houten, Bennett ; Schatten, Gerald articleopenAccess
2819-Sep-2018Estimulação angiogénica de tecido ovárico criopreservadoReis, Maria Carolina Pereira masterThesisembargoedAccess
2913-Sep-2013Estudo de subpopulações de espermatozóides com base no conteúdo em espécies reativas de oxigénio mitocondriaisMarques, Mónica João da Conceição masterThesisclosedAccess
3017-Sep-2019Evaluation of ageing-related molecular and bioenergetic alterations in bovine oocytesSoares, Maria MoreiramasterThesisclosedAccess
312013Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilizationTavares, R. S. ; Silva, A. F. ; Lourenço, B. ; Almeida-Santos, T. ; Sousa, A. P. ; Ramalho-Santos, J. articleopenAccess
322006Flow cytometry evaluation of lead and cadmium effects on mouse spermatogenesisOliveira, Helena ; Loureiro, João ; Filipe, Luísa ; Santos, Conceição ; Ramalho-Santos, João ; Sousa, Mário ; Pereira, Maria de Lourdes articleopenAccess
332002Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliabilityNunes-Correia, Isabel ; Eulálio, Ana ; Nir, Shlomo ; Düzgünes, Nejat ; Ramalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
3428-Dec-2017Framing Pluripotency: from gene to imagePerestrelo, Tânia Marisa Melim doctoralThesisembargoedAccess
352008Freeze-dried primate sperm retains early reproductive potential after intracytoplasmic sperm injectionSánchez-Partida, Luis Gabriel ; Simerly, Calvin R. ; Ramalho-Santos, João articleopenAccess
362001Fusion and Infection of Influenza and Sendai Viruses as Modulated by Dextran Sulfate: A Comparative StudyRamalho-Santos, João ; Lima, Maria Pedroso de articleopenAccess
372011Generation of a reporter system for monitorization of endothelial differentiationLima, Ana Francisca Silva de masterThesisopenAccess
3823-Mar-2015Generation of a VASA/GDF-9/ZP3-promoter driven triple transgenic reporter mouse line as a tool to study ovarian dynamicsCordeiro, Marília Henriques doctoralThesisopenAccess
39May-2002Golgi apparatus dynamics during mouse oocyte in vitro maturation: effect of the membrane trafficking inhibitor brefeldin AMoreno, Ricardo D. ; Schatten, Gerald ; Ramalho-Santos, João articleopenAccess
409-Nov-2020Heavy Metal Exposure And Its Effects In Male Reproductive Health: An In Vivo And In Vitro StudyCarola, Carolina MatosmasterThesisembargoedAccess
4110-Sep-2020High Fructose Feeding and Hepatic Fatty Liver Disease Inflammation: The Role of Intestinal MicrobiotaSilva, João Carlos Pinho da doctoralThesisopenAccess
422006Histopathological Effects of Hexavalent Chronium in Mouse KidneyOliveira, H. ; Santos, T. M. ; Ramalho-Santos, J. ; Pereira, M. de Lourdes articleopenAccess
432008Human sperm mitochondrial function : implications for male (in)fertilityAmaral, Maria Alexandra Barreto doctoralThesisopenAccess
4430-Jul-2015Human sperm mobility: proteins and metabolites towards the same journey's endPaiva, Carla Patrícia Rodrigues doctoralThesisopenAccess
4516-May-2011In Vitro Surfactant Structure-Toxicity Relationships: Implications for Surfactant Use in Sexually Transmitted Infection Prophylaxis and ContraceptionInácio, Ângela S. ; Mesquita, Katia A. ; Baptista, Marta ; Ramalho-Santos, João ; Vaz, Winchil L. C. ; Vieira, Otília V. articleopenAccess
462011Infertilidade equina : múltiplas fragilidades ou um "fado" do espermatozóideGamboa, Sandra Cristina de Oliveira Pinto doctoralThesisopenAccess
471998The influenza virus hemagglutinin: a model protein in the study of membrane fusionRamalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
482012Influência dos abusos estudantis durante os festejos académicos nos espermatozóidesAlmeida, Ana Karina Lopes masterThesisopenAccess
492-Dec-2013Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell PluripotencySandro, L. Pereira ; Grãos, Mário ; Rodrigues, Ana Sofia ; Anjo, Sandra I. ; Carvalho, Rui A. ; Oliveira, Paulo J. ; Arenas, Ernest ; Ramalho-Santos, João articleopenAccess
502014Insights into the reproductive dysfunction in diabetes : an in vitro approachPortela, Joana Mafalda Diogo masterThesisopenAccess
5119-Jan-1999Interactions of Influenza Virus with Cultured Cells: Detailed Kinetic Modeling of Binding and EndocytosisNunes-Correia, Isabel ; Ramalho-Santos, João ; Nir, Shlomo ; Lima, Maria C. Pedroso de articleopenAccess
521992Kinetic modeling of Sendai virus fusion with PC-12 cells. Effect of pH and temperature on fusion and viral inactivationLima, Maria da Conceição Pedroso de ; Ramalho-Santos, João ; Martins, Maria de Fátima ; Carvalho, Arsélio Pato de ; Bairos, Vasco ; Nir, Shlomo articleopenAccess
5328-Jan-2010Linking open chromatin to pluripotency in ES cells : the role of the chromatin remodeler Chd1Maia, Alexandre Gaspar doctoralThesisopenAccess
542003LIS1 association with dynactin is required for nuclear motility and genomic union in the fertilized mammalian oocytePayne, Christopher ; John, Justin C. St. ; Ramalho-Santos, João ; Schatten, Gerald articleopenAccess
552015Mechanisms and possible function of SIRT3 in mESCRibeiro, Marcelo Filipe Maleiro masterThesisopenAccess
561-Dec-2014Mechanisms of induced pluripotency: The role of the Nucleosome Remodelling and Deacetylase complexSantos, Rodrigo Luiz dos doctoralThesisembargoedAccess
5727-Jan-2016Mechanisms underlying metabolic shift in pluripotent stem cells: The potential role of sirtuinsCorreia, Marcelo José Marques doctoralThesisopenAccess
582001Membrane Trafficking Machinery Components Associated with the Mammalian Acrosome during SpermiogenesisRamalho-Santos, João ; Moreno, Ricardo D. ; Wessel, Gary M. ; Chan, Edward K. L. ; Schatten, Gerald articleopenAccess
5921-Dec-2020Metabolic modulation in paused-like pluripotencySousa, Maria Inês Ramalho de Almeida edoctoralThesisembargoedAccess
602013Mitochondria and mammalian reproductionRamalho-Santos, J. ; Amaral, Sandra articleopenAccess
612013Mitochondria functionality and sperm qualityAmaral, Alexandra ; Lourenço, Bárbara ; Marques, Mónica ; Ramalho-Santos, J. articleopenAccess
6219-May-2010Mitochondria modulate pluripotency in human embryonic stem cellsVarum, Sandra Filipa Tavares doctoralThesisembargoedAccess
6330-Apr-2009Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)--A model for endangered speciesMota, Paula ; Amaral, Sandra ; Martins, Luís ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
642009A mitocôndria testicular como novo modelo toxicológico para avaliar correctamente o efeito de poluentes ambientais na reprodução masculina : estudo comparativo do impacto do DDE [1,1 -dicloro-2,2-bis(p-clorofenil)etileno] e TCDD (2,3,7,8-tetraclorodibenzo-p-dioxina) na bioenergética mitocondrial de testículo e fígadoCordeiro, Marília Henriques masterThesisopenAccess
65Mar-2004Mouse genetic corneal disease resulting from transgenic insertional mutagenesisRamalho, J. S. ; Gregory-Evans, K. ; Huxley, C. ; Seabra, M. C. articleopenAccess
6623-Mar-2011Not All Sperm Are Equal: Functional Mitochondria Characterize a Subpopulation of Human Sperm with Better Fertilization PotentialSousa, Ana Paula ; Amaral, Alexandra ; Baptista, Marta ; Tavares, Renata ; Caballero Campo, Pedro ; Caballero Peregrín, Pedro ; Freitas, Albertina ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, João articleopenAccess
672013p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrationsTavares, Renata S. ; Mansell, Steven ; Barratt, Christopher L. R. ; Wilson, Stuart M. ; Publicover, Stephen J. ; Ramalho-Santos, João articleopenAccess
682009Parabens in male infertility--Is there a mitochondrial connection?Tavares, Renata S. ; Martins, Fátima C. ; Oliveira, Paulo J. ; Ramalho-Santos, João ; Peixoto, Francisco P. articleopenAccess
6927-Sep-1996Partial fusion activity of influenza virus toward liposomes and erythrocyte ghosts is distinct from viral inactivationRamalho-Santos, João ; Lima, Maria C. Pedroso de ; Nir, Shlomo articleopenAccess
702014Preservação da fertilidade: maturação in vitro de oócitos pré ou pós vitrificaçãoMachado, Solange dos Santos Carril masterThesisopenAccess
71May-2020Publicly stressing the role of mitochondria in NAFLD with(in) a sports eventAlemany-Pagès, Mireia; Tavares, Rui Miguel dos Santos ; Varela Amaral, Sara; Barros-Viegas, Ana Teresa; Oliveira, Paulo J. ; Santos, João Ramalho de Sousa ; Azul, Anabela Marisa de Jesus Rodrigues articleembargoedAccess
722008The quantification of lipid and protein oxidation in stallion spermatozoa and seminal plasma: Seasonal distinctions and correlations with DNA strand breaks, classical seminal parameters and stallion fertilityMorte, Maria Inês ; Rodrigues, Ana Margarida ; Soares, Diana ; Rodrigues, Ana Sofia ; Gamboa, Sandra ; Ramalho-Santos, João articleopenAccess
7320-Sep-2018Quiet! They May Be at Rest: Metabolic Regulation of Paused Pluripotency.Silva, Bibiana Correia da masterThesisembargoedAccess
7418-Sep-2008Regulation of apoptosis and differentiation by P53 in human embryonic stem cellsGrandela, Ana Catarina Martins doctoralThesisopenAccess
7516-Mar-1999Role of a Transbilayer pH Gradient in the Membrane Fusion Activity of the Influenza Virus Hemagglutinin: Use of the R18 Assay to Monitor Membrane MergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
762004The role of target membrane sialic acid residues in the fusion activity of the influenza virus: the effect of two types of ganglioside on the kinetics of membrane mergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
772012Selecção de ovócitos para as técnicas de reprodução assistida com base no estudo das células do CumuolusLourenço, Bárbara Sofia Leitão Pinhão masterThesisopenAccess
781-Sep-2008Seminal traits, suitability for semen preservation and fertility in the native Portuguese horse breeds Puro Sangue Lusitano and Sorraia: Implications for stallion classification and assisted reproductionGamboa, Sandra ; Machado-Faria, Manuel ; Ramalho-Santos, João articleopenAccess
791998Sendai Virus Fusion Activity as Modulated by Target Membrane ComponentsNunes-Correia, Isabel ; Ramalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
802004Simultaneous analysis of cytoskeletal patterns and chromosome positioning in human fertilization failuresRamalho-Santos, João ; Amaral, Alexandra ; Brito, Raquel ; Freitas, Mariana ; Santos, Teresa Almeida articleopenAccess
812005SNARE proteins and caveolin-1 in stallion spermatozoa: possible implications for fertilityGamboa, Sandra ; Ramalho-Santos, João articleopenAccess
822000SNAREs in Mammalian Sperm: Possible Implications for FertilizationRamalho-Santos, João ; Moreno, Ricardo D. ; Sutovsky, Peter ; Chan, Anthony Wing-Sang ; Hewitson, Laura ; Wessel, Gary M. ; Simerly, Calvin R. ; Schatten, Gerald articleopenAccess
8315-Jul-2020Sperm quality in patients with infertility of unknown origin.Cristo, Maria Inês SousamasterThesisembargoedAccess
84Aug-2008Surfactants as microbicides and contraceptive agents: a systematic in vitro studyVieira, Otilia V. ; Hartmann, Diego O. ; Cardoso, Carla M. P. ; Oberdoerfer, Daniel ; Baptista, Marta ; Santos, Manuel A. S. ; Almeida, Luis ; Ramalho-Santos, João: articleopenAccess
852008Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leakAmaral, Sandra ; Mota, Paula ; Rodrigues, Ana Sofia ; Martins, Luís ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
862009Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic ratsAmaral, Sandra ; Mota, Paula C. ; Lacerda, Beatriz ; Alves, Marco ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
8713-Feb-2014The role of metabolism and mitochondrial function in embryonic stem cellsRodrigues, Ana Sofia doctoralThesisembargoedAccess
8815-Jul-2014A two-sided tale : the influence of environmental endocrine disruptors and sperm chromatin status on male fertilitySantos Tavares, Renata doctoralThesisopenAccess
896-Sep-2021Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional studyAzul, Anabela Marisa ; Almendra, Ricardo ; Quatorze, Marta; Loureiro, Adriana ; Reis, Flávio ; Tavares, Rui ; Mota-Pinto, Anabela ; Cunha, António ; Rama, Luís ; Malva, João Oliveira ; Santana, Paula ; Santos, João Ramalho ; HeaLIQs4Cities, consortiumarticleopenAccess
909-Apr-2014Unraveling the mechanisms of spermicidal activity by surfactants: their potential use as multi-functional compoundsBaptista, Marta Isabel Rodrigues doctoralThesisopenAccess
912013UVB irradiation as a tool to assess ROS-induced damage in human spermatozoaAmaral, S. ; Redmann, K. ; Sanchez, V. ; Mallidis, C. ; Ramalho-Santos, J. ; Schlatt, S. articleopenAccess
922002VAMP/synaptobrevin as an acrosomal marker for human spermRamalho-Santos, João ; Terada, Yukihiro ; Schatten, Gerald articleopenAccess
932010Vias metabólicas e funcionalidade de espermatozóides humanosPaiva, Carla Patrícia Rodrigues masterThesisopenAccess