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Credit Name
Cunha-Oliveira, Teresa
 
Name
Cunha-Oliveira, Teresa
 
Variants
Oliveira, M.T.
Cunha-Oliveira, T.
Oliveira, T.C.
 
Email
teresa.oliveira@uc-biotech.pt
 
 
 
Scopus Author ID
 
Researcher ID
 
Status
UC Researcher
Biography
Teresa Cunha-Oliveira got her PhD in Biology (Cell Biology) in 2007 from the University of Coimbra (Portugal), having contributed to introduce the role of mitochondria in the field of drug addiction, particularly concerning cocaine, heroin and amphetamine. In her first post-doctoral period (2007-2010) in the Center for Neuroscience and Cell Biology (CNC, Coimbra), she collaborated with a Medicinal Chemistry group at the University of Porto to uncover the cellular effects of a newly found chemical interaction between heroin and cocaine (speedball) that could have a great impact in the understanding of poly-drug abuse consequences. In her second post-doctoral period (2010-2012), she was focused on the role of mitochondria in neurodegenerative diseases, including Huntington’s disease (HD) and Parkinson’s disease. She became interested in the epigenetic mechanisms associated with long-term mitochondrial dysfunction and contributed to characterize the bioenergetic dysfunction in cybrids from HD patients, evidencing the involvement of pyruvate dehydrogenase (PDH) and the promising role of epigenetic modulators in reversing PDH and mitochondrial dysfunctions in HD models. From 2013 until now, she is part of the MitoXT group at the CNC, more interested in the role of mitochondria in drug toxicology and experimental therapeutics, especially doxorubicin (DOX), an anticancer agent with long-term cardiotoxic side-effects involving mitochondria. She contributed to describe DOX-induced mitochondrial dysfunction, transcriptional deregulation and epigenetic signalling using in vitro and in vivo models. Her current interests include the development and validation of innovative screening assays to assess mitochondrial health with applications in toxicology, diagnostics and development of innovative therapeutic strategies for personalized medicine.
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Publications
(All)

Results 1-63 of 63 (Search time: 0.001 seconds).

Issue DateTitleAuthor(s)TypeAccess
1Feb-2015Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human LymphoblastsNaia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina articleopenAccess
22013Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondriaCunha-Oliveira, Teresa ; Silva, Lisbeth ; Silva, Ana Maria ; Moreno, António J. ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
32007Adaptation to oxidative stress in the chronic effects of cocaine and amphetamineCunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. articleopenAccess
41-Sep-2017Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicityFerreira, André ; Cunha-Oliveira, Teresa ; Simões, Rui F. ; Carvalho, Filipa S. ; Burgeiro, Ana ; Nordgren, Kendra ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
52015Analysis of pro-apoptotic protein trafficking to and from mitochondriaVega-Naredo, Ignacio ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
617-Mar-2017Aula de Campo e Aula de Museu: Recursos didáticos para conteúdos com Paleontologia nos Ensinos Básico e SecundárioAzenha, Matilde Lopes de Oliveira doctoralThesisopenAccess
72009BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neuronsAlmeida, S. ; Laço, M. ; Cunha-Oliveira, T. ; Oliveira, C. R. ; Rego, A. C. articleopenAccess
8Nov-2017Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblastsCoelho, Ana R. ; Martins, Tatiana R. ; Couto, Renata ; Deus, Cláudia ; Pereira, Cláudia V. ; Simões, Rui F. ; Rizvanov, Albert A. ; Silva, Filomena ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. ; Serafim, Teresa L. articleopenAccess
9Sep-2011Bioenergetic dysfunction in Huntington's disease human cybridsFerreira, I. Luísa ; Cunha-Oliveira, Teresa ; Nascimento, Maria V. ; Ribeiro, Márcio ; Proença, M. Teresa ; Januário, Cristina ; Oliveira, Catarina R. ; Rego, A. Cristina articleopenAccess
102008Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugsCunha-Oliveira, Teresa ; Rego, Ana Cristina ; Oliveira, Catarina R. articleopenAccess
1114-Oct-2023Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate ModelPereira, Susana P. ; Diniz, Mariana S. ; Tavares, Ludgero C. ; Cunha-Oliveira, Teresa ; Li, Cun; Cox, Laura A ; Nijland, Mark J. ; Nathanielsz, Peter W. ; Oliveira, Paulo J. articleopenAccess
12Feb-2012Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathwaysCunha-Oliveira, Teresa ; Ferreira, Ildete L. ; Rego, A. Cristina bookPartopenAccess
13Nov-2021Corrigendum to 'A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients'. [Redox Biology 45 (2021) 102037]Deus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Teixeira, José ; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda; Raimundo, Nuno ; Oliveira, Paulo J. articleopenAccess
142005Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxideCunha-Oliveira, T. ; Rego, A. C. ; Morgadinho, M. T. ; Sarmento, A. ; Macedo, T. ; Oliveira, C. R. conferenceObjectopenAccess
152006Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxideCunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, Maria Teresa ; Macedo, Tice ; Oliveira, Catarina Resende articleopenAccess
162013Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transitionBernardo, Telma C. ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Holy, Jon ; Krasutsky, Dmytro ; Kolomitsyna, Oksana ; Krasutsky, Pavel ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
17Sep-2012Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in micePereira, Frederico ; Cunha-Oliveira, Teresa ; Viana, Sofia ; Travassos, Ana Sofia ; Nunes, Sara ; Silva, Carlos ; Prediger, Rui ; Rego, Ana Cristina ; Ali, Syed ; Fontes Ribeiro, Carlos Alberto articleclosedAccess
1825-Nov-2019Doxorubicin persistently rewires cardiac circadian homeostasis in miceFerreira, Luciana L ; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição ; Cunha-Oliveira, Teresa ; Sassone-Corsi, Paolo; Oliveira, Paulo J. articleembargoedAccess
192018Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytesCunha-Oliveira, Teresa ; Ferreira, Luciana L ; Coelho, Ana Raquel ; Deus, Cláudia M ; Oliveira, Paulo J articleopenAccess
202009Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGFAlmeida, Sandra ; Cunha-Oliveira, Teresa ; Laço, Mário ; Oliveira, Catarina R. ; Rego, A. Cristina articleopenAccess
219-Mar-2012Efeito crónico da heroína e do peróxido de hidrogénio em células PC12Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, M. Teresa ; Macedo, Tice R. ; Oliveira, Catarina R. articleopenAccess
223-Dec-2020Effects of Extended Passaging on the BEAS-2B Cell Line, an in vitro Model of Human Lung Epithelium Established for the Study of Lung CarcinogenesisSobral, Margarida Conceição MoreiramasterThesisembargoedAccess
2310-Mar-2022Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational StatisticsSimões, Rui F. ; Oliveira, Paulo J. ; Oliveira, Teresa Cunha ; Pereira, Francisco B. articleopenAccess
2421-Sep-2018Experimental enhancement of cellular OXPHOS reliance for mitochondrial health assessments - Development and characterization of a rapid and efficient method to induce OXPHOS in skin fibroblasts, for the assessment of mitochondiral toxicity and protection.Costa, Cláudio Figueiredo masterThesisopenAccess
258-Mar-2012Expression of NR1/NR2B N-Methyl-d-Aspartate Receptors Enhances Heroin Toxicity in HEK293 CellsDomingues, António ; Cunha-Oliveira, Teresa ; Laço, Mário L. N. ; Macedo, Tice ; Oliveira, Catarina R. ; Rego, A. Cristina articleopenAccess
2615-Nov-2012Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cellsRibeiro, Márcio ; Rosenstock, Tatiana ; Cunha-Oliveira, Teresa ; Ferreira, Ildete ; Oliveira, Catarina R. ; Rego, Ana Cristina articleopenAccess
272005Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosisCunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. articleopenAccess
28Aug-2018Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cellsAbreu, Patrícia L. ; Cunha-Oliveira, Teresa ; Ferreira, Leonardo M R ; Urbano, Ana M. articleopenAccess
298-Mar-2017Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's DiseaseNaia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina articleopenAccess
303-Oct-2019Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic StressFerreira, Leonardo M. R. ; Cunha-Oliveira, Teresa ; Sobral, Margarida C. ; Abreu, Patrícia L. ; Alpoim, Maria Carmen ; Urbano, Ana M. articleopenAccess
319-Dec-2020Impact of Rebaudioside A in cancer cell metabolism: Potential as a safe chemotherapeutic adjuvantAfonso, Gonçalo José Martins masterThesisopenAccess
3218-Sep-2019Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's DiseaseValdinocci, Dario; Simões, Rui F. ; Kovarova, Jaromira ; Cunha-Oliveira, Teresa ; Neuzil, Jiri ; Pountney, Dean LarticleopenAccess
33Aug-2016Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicitySilva, Ana Marta ; Barbosa, Inês A. ; Seabra, Cátia ; Beltrão, Nuno ; Santos, Raquel ; Vega-Naredo, Ignacio ; Oliveira, Paulo ; Cunha-Oliveira, Teresa articleopenAccess
34Mar-2016Ketogenic diets: from cancer to mitochondrial diseases and beyondBranco, Ana F. ; Ferreira, André ; Simões, Rui F. ; Magalhães-Novais, Sílvia ; Zehowski, Cheryl ; Cope, Elisabeth ; Silva, Ana Marta ; Pereira, Daniela ; Sardão, Vilma A. ; Cunha-Oliveira, Teresa articleopenAccess
352013Medical Toxicology of Drugs of AbuseCunha-Oliveira, Teresa ; Rego, Ana Cristina ; Carvalho, Félix ; Oliveira, Catarina R. bookPartopenAccess
361-Jul-2018Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative CapacityPereira, Susana P. ; Deus, Cláudia M. ; Serafim, Teresa L. ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. articleopenAccess
3710-May-2023Metabolic Priming as a Tool in Redox and Mitochondrial TheragnosticsPinho, Sónia A. ; Anjo, Sandra I. ; Cunha-Oliveira, Teresa articleopenAccess
3816-Sep-2019Mitochondria-based screening of drug neurotoxicity in differentiated SH-SY5Y cellsFerrão, Rafaela Margarida CuramasterThesisembargoedAccess
3916-Jul-2022Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systemsAmorim, Ricardo ; Simões, Inês C. M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana ; Tavares, Ludgero C. ; Benfeito, Sofia; Pereira, Susana P.; Simões, Rui F. ; Karkucinska-Wieckowska, Agnieszka; Viegas, Ivan ; Szymanska, Sylwia; Dąbrowski, Michał; Janikiewicz, Justyna; Cunha-Oliveira, Teresa ; Dobrzyń, Agnieszka; Jones, John Griffith ; Borges, Fernanda; Wieckowski, Mariusz R. ; Oliveira, Paulo J.articleopenAccess
402021A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patientsDeus, Cláudia M. ; Pereira, Susana P.; Cunha-Oliveira, Teresa ; Teixeira, José; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda; Raimundo, Nuno ; Oliveira, Paulo J.articleopenAccess
41Dec-2014Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblastsMoreira, Ana C. ; Branco, Ana F. ; Sampaio, Susana F. ; Cunha-Oliveira, Teresa ; Martins, Tatiana R. ; Holy, Jon ; Oliveira, Paulo J. ; Sardão, Vilma A. articleopenAccess
421-May-2013Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondriaCunha-Oliveira, Teresa ; Silva, Lisbeth ; Silva, Ana Maria ; Moreno, António J. ; Oliveira, Catarina R. ; Santos, Maria S. articleopenAccess
432006Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamineCunha-Oliveira, T. ; Rego, A. C. ; Cardoso, S. M. ; Borges, F. ; Swerdlow, R. ; Macedo, T. ; Oliveira, C. R. articleopenAccess
442020Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defectsDeus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Pereira, Francisco B. ; Raimundo, Nuno Filipe Viegas das Neves ; Oliveira, Paulo J. articleembargoedAccess
452011Molecular interaction between cocaine and opioids. Implications on Speedball's toxicityCunha-Oliveira, T. ; Silva, L. ; Silva, A. M. ; Santos, M. S. ; Garrido, J. ; Borges, F. ; Rego, A. C. ; Oliveira, C. R. conferenceObjectopenAccess
462021MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic ProfileJacinto, Sandra; Guerreiro, Patrícia; Oliveira, Rita Machado de; Oliveira, Teresa Cunha ; Santos, Maria João ; Grazina, Manuela ; Rego, A. Cristina ; Outeiro, Tiago F. articleopenAccess
477-Nov-2007Neuronal dysfunction induced by drugs of abuseOliveira, Maria Teresa Martins da Cunha doctoralThesisopenAccess
4820-Jul-2021Neuronal mitochondrial metabolism and dynamic profiling under physiological and pathological conditions using biological-based machine learning approachesSimões, Rui Fernando Vieira Lisboa Matias doctoralThesisembargoedAccess
492012Neurotoxicity of cocaineCunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. bookPartopenAccess
508-Mar-2012Neurotoxicity of heroin-cocaine combinations in rat cortical neuronsCunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina R. articleopenAccess
5128-Aug-2014Oxidative Stress and Drugs of Abuse: An UpdateCunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. articleopenAccess
522020Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological InterventionCunha-Oliveira, Teresa ; Montezinho, Liliana ; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J. ; Silva, Filomena S. G. articleopenAccess
532021Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamineSimões, Rui F. ; Pino, Rute; Soares, Maurício Moreira ; Kovarova, Jaromira ; Neuzil, Jiri ; Travasso, Rui ; Oliveira, Paulo J.; Cunha-Oliveira, Teresa ; Pereira, Francisco B.articleopenAccess
545-Feb-2019Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer CellsBajzikova, Martina ; Kovarova, Jaromira ; Coelho, Ana R. ; Boukalova, Stepana ; Oh, Sehyun ; Rohlenova, Katerina ; Svec, David ; Hubackova, Sona ; Endaya, Berwini ; Judasova, Kristyna ; Bezawork-Geleta, Ayenachew ; Kluckova, Katarina ; Chatre, Laurent ; Zobalova, Renata ; Novakova, Anna ; Vanova, Katerina ; Ezrova, Zuzana ; Maghzal, Ghassan J ; Magalhaes Novais, Silvia ; Olsinova, Marie ; Krobova, Linda ; An, Yong Jin ; Davidova, Eliska ; Nahacka, Zuzana ; Sobol, Margarita ; Cunha-Oliveira, Teresa ; Sandoval-Acuña, Cristian ; Strnad, Hynek ; Zhang, Tongchuan ; Huynh, Thanh ; Serafim, Teresa L. ; Hozak, Pavel ; Sardão, Vilma A. ; Koopman, Werner J H ; Ricchetti, Miria ; Oliveira, Paulo J ; Kolar, Frantisek ; Kubista, Mikael ; Truksa, Jaroslav ; Dvorakova-Hortova, Katerina ; Pacak, Karel ; Gurlich, Robert ; Stocker, Roland ; Zhou, Yaoqi ; Berridge, Michael V ; Park, Sunghyouk ; Dong, Lanfeng ; Rohlena, Jakub ; Neuzil, Jiri articleembargoedAccess
55Sep-2013Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abusePerfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina articleopenAccess
561-Nov-2012Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abusePerfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina articleopenAccess
572017Role of Mitochondria on the Neurological Effects of CocainePereira, S.P. ; Cunha-Oliveira, T. articleopenAccess
58Jan-2015Role of mtDNA-related mitoepigenetic phenomena in cancerFerreira, André ; Serafim, Teresa L. ; Sardão, Vilma A. ; Cunha-Oliveira, Teresa articleopenAccess
5914-May-2021Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reductionPereira, Susana P. ; Tavares, Ludgero C. ; Duarte, Ana I. ; Baldeiras, Inês ; Cunha-Oliveira, Teresa ; Martins, João D. ; Santos, Maria S. ; Maloyan, Alina; Moreno, Antonio J. ; Cox, Laura A. ; Li, Cun; Nathanielsz, Peter W. ; Nijland, Mark J. ; Oliveira, Paulo J. articleembargoedAccess
60Feb-2019Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblastsFerreira, Luciana L. ; Cunha-Oliveira, Teresa ; Veloso, Caroline D. ; Costa, Cláudio F. ; Wallace, Kendall B. ; Oliveira, Paulo J. articleembargoedAccess
612007Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neuronsCunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina Resende articleopenAccess
62Oct-2006Synthesis and Cytotoxic Profile of 3,4-Methylenedioxymethamphetamine (“Ecstasy”) and Its Metabolites on Undifferentiated PC12 Cells: A Putative Structure−Toxicity RelationshipMilhazes, Nuno ; Cunha-Oliveira, Teresa ; Martins, Pedro ; Garrido, Jorge ; Oliveira, Catarina ; Rego, A. Cristina ; Borges, Fernanda articleopenAccess
632014β-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?Branco, Ana F. ; Moreira, Ana C. ; Cunha-Oliveira, Teresa ; Couto, Renata ; Sardão, Vilma A. ; Rizvanov, Albert A. ; Palotas, Andras ; Oliveira, Paulo J. articleopenAccess