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https://hdl.handle.net/10316/84853
Title: | Medical Toxicology of Drugs of Abuse | Authors: | Cunha-Oliveira, Teresa Rego, Ana Cristina Carvalho, Félix Oliveira, Catarina R. |
Issue Date: | 2013 | Serial title, monograph or event: | Principles of Addiction - Comprehensive Addictive Behaviors and Disorders | Volume: | 1 | Abstract: | This chapter describes the toxicological properties of the main drugs of abuse, namely alcohol, amphetamines, cocaine, heroin, and cannabis. All these drugs share chemical similarities with neuronal endogenous compounds and are thus psychoactive. Besides the nervous system, drugs of abuse affect other body systems, inducing cardiovascular, metabolic, hepatic, renal, respiratory, reproductive, and immune impairments, explaining the medical complications observed in drug addicts. The fact that the toxicity of these drugs may be affected by the interactions with other substances, namely on polydrug abuse and street drug adulteration, is also highlighted. A comparative view of the medical toxicological effects as well as the pharmacokinetic and pharmacodynamic characteristics of these drugs of abuse are presented. | URI: | https://hdl.handle.net/10316/84853 | ISBN: | 9780123983367 | DOI: | 10.1016/B978-0-12-398336-7.00017-6 | Rights: | openAccess |
Appears in Collections: | I&D CNC - Capítulos (ou partes) de Livros |
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C_Cunha-Oliveira Chapter Medical Toxicology of Drugs of Abuse.pdf | 551.44 kB | Adobe PDF | View/Open |
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