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12021PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neuronsFerreira-Marques, Marisa ; Carvalho, André ; Cavadas, Cláudia ; Aveleira, Célia A. articleopenAccess
217-Jan-2020SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent MannerRamos, Helena; Calheiros, Juliana; Almeida, Joana; Barcherini, Valentina; Santos, Sónia ; Carvalho, Alexandra T. P. ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
321-Oct-2020Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer's Disease Cellular ModelsSilva, Ana ; Pereira, Marta ; Carrascal, Mylène A. ; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia ; Resende, Rosa ; Silva, Maria Manuel ; Santos, Armanda E. ; Pereira, Cláudia ; Cruz, Maria Teresa articleopenAccess
41-Oct-2020SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital GlaucomaYoung, Terri L.; Whisenhunt, Kristina N.; Jin, Jing; LaMartina, Sarah M.; Martin, Sean M.; Souma, Tomokazu; Limviphuvadh, Vachiranee; Suri, Fatemeh; Souzeau, Emmanuelle; Zhang, Xue; Dan, Yongwook; Anagnos, Evie; Carmona, Susana ; Jody, Nicole M.; Stangel, Nickie; Higuchi, Emily C.; Huang, Samuel J.; Siggs, Owen M.; Simões, Maria José; Lawson, Brendan M.; Martin, Jacob S.; Elahi, Elahe; Narooie-Nejad, Mehrnaz; Motlagh, Behzad Fallahi; Quaggin, Susan E.; Potter, Heather D.; Silva, Eduardo D. ; Craig, Jamie E.; Egas, Conceição ; Maroofian, Reza; Maurer-Stroh, Sebastian; Bradfield, Yasmin S.; Tompson, Stuart W.articleopenAccess
522-Feb-2020The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and InfectionRosário-Ferreira, Nícia ; Preto, Antonio J. ; Melo, Rita ; Moreira, Irina S. ; Brito, Rui M. M. articleopenAccess
611-Jul-2020The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial FunctionTeodoro, João S. ; Amorim, João A. ; Machado, Ivo F. ; Castela, Ana C. ; Steegborn, Clemens; Sinclair, David A; Rolo, Anabela P. ; Palmeira, Carlos M. articleopenAccess
79-Aug-2020Polyethylene Glycol 35 as a Perfusate Additive for Mitochondrial and Glycocalyx Protection in HOPE Liver PreservationPanisello Rosello, Arnau; Silva, Rui Teixeira da ; Castro, Carlos ; Bardallo, Raquel G.; Calvo, Maria; Folch-Puy, Emma; Carbonell, Teresa ; Palmeira, Carlos ; Roselló-Catafau, Joan ; Adam, René articleopenAccess
86-Mar-2020Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbataOliveira, Cátia S. D.; Moreira, Patrícia ; Resende, Judite; Cruz, Maria T. ; Pereira, Cláudia F. ; Silva, Artur M. S. ; Santos, Sónia A. O. ; Silvestre, Armando J. D. articleopenAccess
97-Jul-2020Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and miceWilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, MatthisarticleopenAccess
1014-Jan-2022Design and Evaluation of a Lactate Microbiosensor: Toward Multianalyte Monitoring of Neurometabolic Markers In Vivo in the BrainFernandes, Eliana ; Ledo, Ana ; Barbosa, Rui M. articleopenAccess
112020Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal SynapsesPandian, Swarna; Zhao, Jian-Ping; Murata, Yasunobu; Bustos, Fernando J; Tunca, Cansu; Almeida, Ramiro D. ; Constantine-Paton, MarthaarticleopenAccess
122022Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD MiceFernandes, Adelaide; Caldeira, Cláudia; Cunha, Carolina; Ferreiro, Elisabete ; Vaz, Ana Rita; Brites, Dora articleopenAccess
13Dec-2021The transcription factor Ndt80 is a repressor of Candida parapsilosis virulence attributesBranco, Joana; Martins-Cruz, Cláudia; Rodrigues, Lisa ; Silva, Raquel M.; Araújo-Gomes, Nuno; Gonçalves, Teresa ; Miranda, Isabel M.; Rodrigues, Acácio G.articleopenAccess
143-May-2020Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healingPonte, Susana; Carvalho, Lara; Gagliardi, Maria; Campos, Isabel; Oliveira, Paulo J. ; Jacinto, António articleopenAccess
158-Feb-2021Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph diseaseDuarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de articleopenAccess
1618-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
1731-May-2021Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activityMele, Miranda ; Vieira, Ricardo ; Correia, Bárbara ; Luca, Pasqualino De ; Duarte, Filipe V. ; Pinheiro, Paulo S. ; Duarte, Carlos B. articleopenAccess
1823-Jan-2020Control of glutamate release by complexes of adenosine and cannabinoid receptorsKöfalvi, Attila ; Moreno, Estefanía; Cordomí, Arnau; Cai, Ning-Sheng; Fernández-Dueñas, Victor; Ferreira, Samira G. ; Guixà-González, Ramón; Sánchez-Soto, Marta; Yano, Hideaki; Casadó-Anguera, Verònica; Cunha, Rodrigo A. ; Sebastião, Ana Maria; Ciruela, Francisco ; Pardo, Leonardo; Casadó, Vicent; Ferré, Sergi articleopenAccess
19Jun-2021Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical useCardoso, Renato M. S.; Rodrigues, Sílvia C. ; Gomes, Claudia F.; Duarte, Filipe V. ; Romao, Maryse; Leal, Ermelindo C. ; Freire, Patricia C.; Neves, Ricardo ; Correia, Joana Simões articleopenAccess
209-Nov-2021Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucomaGeva, Michal; Gershoni-Emek, Noga; Naia, Luana ; Ly, Philip; Mota, Sandra ; Rego, Ana Cristina ; Hayden, Michael R. ; Levin, Leonard A.articleopenAccess
2131-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
22Nov-2020Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signalingBose, Chhanda; Alves, Inês ; Singh, Preeti; Palade, Philip T.; Carvalho, Eugenia ; Børsheim, Elisabet; Jun, Se-Ran; Cheema, Amrita; Boerma, Marjan; Awasthi, Sanjay; Singh, Sharda P.articleopenAccess
232011Visualização da rede linfática profunda usando radioliposomasBotelho, M. F. ; Lima, J. J. P. ; Dormehl, I. C. ; Baganha, M. Fontes; Gomes, C. M. ; Santos, A. C. ; Moreira, J. N. ; Kilian, E.articleopenAccess
248-Mar-2017Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's DiseaseNaia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina articleopenAccess
252016Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial functionPereira, Gonçalo C. ; Pereira, Susana P. ; Tavares, Ludgero C. ; Carvalho, Filipa S. ; Magalhães-Novais, Sílvia ; Barbosa, Inês A. ; Santos, Maria S. ; Bjork, James ; Moreno, António J. ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
26Feb-2015Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human LymphoblastsNaia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina articleopenAccess
27Dec-2014Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblastsMoreira, Ana C. ; Branco, Ana F. ; Sampaio, Susana F. ; Cunha-Oliveira, Teresa ; Martins, Tatiana R. ; Holy, Jon ; Oliveira, Paulo J. ; Sardão, Vilma A. articleopenAccess
28Jan-2009Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety?Pereira, Cláudia V. ; Moreira, Ana C. ; Pereira, Susana P. ; Machado, Nuno G. ; Carvalho, Filipa S. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
29Sep-2009Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?Pereira, Susana P. ; Pereira, Gonçalo C. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
302015Analysis of pro-apoptotic protein trafficking to and from mitochondriaVega-Naredo, Ignacio ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Sardão, Vilma A. ; Oliveira, Paulo J. articleopenAccess
315-Dec-2010Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lungMachado, Nuno G. ; Baldeiras, Inês ; Pereira, Gonçalo C. ; Pereira, Susana P. ; Oliveira, Paulo J. articleopenAccess
324-May-2016Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B AssaySilva, Filomena S. G. ; Starostina, Irina G. ; Ivanova, Vilena V. ; Rizvanov, Albert A. ; Oliveira, Paulo J. ; Pereira, Susana P. articleopenAccess
3312-Jul-2016Understanding the Differential Selectivity of Arrestins toward the Phosphorylation State of the ReceptorSensoy, Ozge ; Moreira, Irina S. ; Morra, Giulia articleembargoedAccess
3412-Jan-2021Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer CellsRodrigo, Ana P.; Mendes, Vera M. ; Manadas, Bruno ; Grosso, Ana R.; Alves de Matos, António P.; Baptista, Pedro V.; Costa, Pedro M.; Fernandes, Alexandra R.articleopenAccess
351-Sep-2017Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicityFerreira, André ; Cunha-Oliveira, Teresa ; Simões, Rui F. ; Carvalho, Filipa S. ; Burgeiro, Ana ; Nordgren, Kendra ; Wallace, Kendall B. ; Oliveira, Paulo J. articleopenAccess
36Apr-2018Graft Protection Against Cold Ischemia Preservation: An Institute George Lopez 1 and Histidine-tryptophan-ketoglutarate Solution AppraisalPanisello-Rosello, A; Castro-Benítez, C; Lopez, A; Balloji, S; Folch-Puy, E; Adam, R; Roselló-Catafau, JarticleembargoedAccess
377-Jul-2021Living Proof of Activity of Extracellular Vesicles in the Central Nervous SystemMahjoum, Shadi; Rufino-Ramos, David; Almeida, Luís Pereira de ; Broekman, Marike L. D.; Breakefield, Xandra O.; van Solinge, Thomas S.articleopenAccess
3829-Apr-2020Standardised comparison of limonene-derived monoterpenes identifies structural determinants of anti-inflammatory activitySousa, Cátia ; Leitão, Alcino Jorge ; Neves, Bruno Miguel ; Judas, Fernando ; Cavaleiro, Carlos ; Mendes, Alexandrina F. articleopenAccess
392015Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like PhenotypeBranco, Ana F. ; Pereira, Susana P. ; Gonzalez, Susana ; Gusev, Oleg ; Rizvanov, Albert A. ; Oliveira, Paulo J. articleopenAccess
4020-Jul-2020Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursorsKim, Ha-Neui; Ponte, Filipa; Nookaew, Intawat; Ucer Ozgurel, Serra; Carvalho, Adriana Marques ; Iyer, Srividhya; Warren, Aaron; Aykin-Burns, Nukhet; Krager, Kimberly; Sardão, Vilma A. ; Han, Li; de Cabo, Rafael; Zhao, Haibo; Jilka, Robert L.; Manolagas, Stavros C.; Almeida, MariaarticleopenAccess
4124-Jul-2019The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurataSilva-Marrero, Jonás I.; Villasante, Juliana; Rashidpour, Ania; Palma, Mariana ; Fàbregas, Anna; Almajano, María Pilar; Viegas, Ivan ; Jones, John G. ; Miñarro, Montserrat; Ticó, Josep R.; Baanante, Isabel V. ; Metón, Isidoro articleopenAccess
422019Understanding and Modulating Immunity With Cell ReprogrammingPires, Cristiana Ferreira ; Rosa, Fábio F. ; Kurochkin, Ilia; Pereira, Carlos Filipe articleopenAccess
434-Sep-2019Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapyCalmeiro, João ; Carrascal, Mylène A. ; Gomes, Célia ; Falcão, Amílcar C. ; Cruz, Maria Teresa ; Neves, Bruno Miguel articleopenAccess
4423-Dec-2018Less Exploited GPCRs in Precision Medicine: Targets for Molecular Imaging and TheranosticsMachado, João Franco; Silva, Rúben D.; Melo, Rita ; Correia, João D. G.articleopenAccess
4513-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa ; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Pinho e Melo, Teresa M. V. D. ; Saraiva, LucíliaarticleembargoedAccess
46Apr-2019Signaling by adenosine receptors-Homeostatic or allostatic control?Cunha, Rodrigo A. articleopenAccess
472008Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damageCardoso, Susana; Santos, Renato X. ; Carvalho, Cristina ; Correia, Sónia ; Pereira, Gonçalo C. ; Pereira, Susana S. ; Oliveira, Paulo J. ; Santos, Maria S. ; Proença, Teresa ; Moreira, Paula I. articleopenAccess
482012Mitochondrionopathy phenotype in doxorubicin-treated Wistar rats depends on treatment protocol and is cardiac-specificPereira, Gonçalo C. ; Pereira, Susana P. ; Pereira, Claudia V. ; Lumini, José A. ; Magalhães, José ; Ascensão, António ; Santos, Maria S. ; Moreno, António J. ; Oliveira, Paulo J. articleopenAccess
4928-Dec-2020Crepis vesicaria L. subsp. taraxacifolia Leaves: Nutritional Profile, Phenolic Composition and Biological PropertiesPedreiro, Sónia ; da Ressurreição, Sandrine; Lopes, Maria ; Cruz, Maria Teresa ; Batista, Teresa ; Figueirinha, Artur ; Ramos, Fernando articleopenAccess
50Dec-2009Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systemsPereira, Susana P. ; Fernandes, Maria A. S. ; Martins, João D. ; Santos, Maria S. ; Moreno, António J. M. ; Vicente, Joaquim A. F. ; Videira, Romeu A. ; Jurado, Amália S. articleopenAccess
Results 1-50 of 313 (Search time: 0.896 seconds).