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Credit Name
Sousa, Hermínio C. de
Full Name
Sousa, Hermínio José Cipriano de
de Sousa, Herminio
de Sousa, H.C.
Sousa, H.C. de
Sousa, Hermínio José Cipriano de
Scopus Author ID
Researcher ID
Hermínio C. de Sousa (HC de Sousa) graduated in Chemical Engineering (5-years Lic. Chem Eng, 1992) from the New University of Lisbon, Portugal. He completed his PhD in 1997, in Chemistry - Physical Chemistry, also at the New University of Lisbon. At the same year he got a Teaching Assistant position at the Chemical Engineering Department, University of Coimbra, Portugal (DEQ-FCTUC), where he currently holds a Tenured Associate Professor position since 2019. He is a Senior Member of the Portuguese Association of Engineers (Portugal) and of the American Institute of Chemical Engineers (AIChE), USA. HC de Sousa has more than 20 years of academic experience in teaching theoretical, theoretical-practical, laboratorial and tutorial/supervision classes at the BSc, MSc and PhD levels. He was also a Visiting Professor/Researcher at the University of Massachusetts-Amherst, USA (2007, 2014), Federal University of Pará, Brazil (2009), UNICAMP, Brazil (2011, 2012), Federal University of Bahia, Brazil (2016, 2017, 2018, 2019), and National University of Colombia, Colombia (2013, 2014, 2017). HC de Sousa is the team leader of the Green and Sustainable Processes Laboratory (GSP), at the Chemical Process Engineering and Forest Products Research Centre of the Chemical Engineering Department of the University of Coimbra (CIEPQPF/DEQ-FCTUC). GSP research strategies and activities are mainly focused on the use of “greener”, sustainable, safer, biomimetic and environmentally-friendly innovative processes for the development of value-added products and materials/nanomaterials which are predominantly envisaged for pharmaceutical/drug delivery and biomedical/tissue engineering applications. However, food, agricultural, nutraceutical, cosmetic, antimicrobial, water treatment, oil & gas, electronics, and low VOC-emission materials/applications are/were also covered. Employed “greener” and sustainable approaches comprise the use of supercritical fluids (e.g., high-pressure, subcritical and supercritical carbon dioxide); of aqueous/ethanolic-based solvent systems; of natural-origin biopolymers and phytochemicals obtained from renewable resources (e.g., from vegetable raw materials and agro-industrial residues/wastes); of ionic liquids (namely of safer/biodegradable ionic liquids), and of “greener”, biomimetic and self-assembly-based synthesis/processing strategies. Several advantageous combinations of these five approaches were/are also implemented. Specific examples of application of the GSP research activities include the development of: nano/microparticles for drug delivery; implants, hydrogels and contact/intraocular lenses for ophthalmic drug delivery; medicated natural-origin wound dressings (namely for diabetic foot ulceration treatment); pre-formed and in-situ forming polymeric implants for prolonged drug/protein release; natural-origin adhesives and bioadhesives; bioactive natural products and their pharmaceutical/biomedical, food, nutraceutical, agricultural and cosmetic formulations/delivery systems; natural-origin flocculants for water treatment; plasticized low-VOC emission PVC/PU materials; and macro-, meso- and microporous silica-based biomaterials (e.g., biomimetic/bioactive biopolymer/silica composite/hybrid biomaterials - drug delivery/hard-tissue applications). More recent research topics include the development of: 1) multifunctional stimuli-responsive and electroactive biomaterials; 2) novel and more efficient materials and nanomaterials for oxygen/CO2/gas capture, storage, delivery and separation; 3) enhanced oil recovery and CO2/water-induced asphaltene precipitation in crude oil reservoirs; 4) improved and eco-friendly agricultural pesticide delivery, biomanagement and pest control (namely for insects/nematodes control); 5) supercritical CO2 as a sterilizing and biocidal agent.
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UC Researcher


Results 1-63 of 63 (Search time: 0.003 seconds).

Issue DateTitleAuthor(s)TypeAccess
128-Sep-2018Biomateriais bio-inspirados à base de sílica para aplicações biomédicas em tecidos durosMiraldo, André Manuel da Costa Patrão masterThesisopenAccess
2Feb-2014Chitosan-based dressings loaded with neurotensin—an efficient strategy to improve early diabetic wound healingMoura, Liane I. F. ; Dias, Ana M. A. ; Leal, Ermelindo C. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
320-Sep-2013Chitosan-based polyionic liquidsGomes, Luís Filipe Ferreira masterThesisembargoedAccess
4Nov-2014Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68Bueno, Cecilia Zorzi ; Dias, Ana Maria Antunes ; de Sousa, Hermínio José Cipriano ; Braga, Mara Elga Medeiros ; Moraes, Angela Maria articleopenAccess
5Sep-2011Desenvolvimento de biomateriais compósitos à base de sílica utilizando técnicas "verdes" e biométricasAlves, Mariline Isabel de Castro masterThesisopenAccess
627-Sep-2018Desenvolvimento de formulações baseadas em atrativos/repelentes para o insecto-vetor do nemátode do pinheiroLeal, Vanessa Monteiro masterThesisembargoedAccess
715-Apr-2015Desenvolvimento de géis injectáveis para libertação controlada e localizada de fármacos em feridasBento, Ana Moniz Côrte-Real Granja masterThesisembargoedAccess
823-Sep-2015Desenvolvimento de lentes de contacto terapêuticas com capacidade de oxigenação melhoradaMendes, Sonia Filipa Xavier masterThesisopenAccess
919-Jul-2018Desenvolvimento e caracterização de polielectrólitos multi-responsivosRosa, Maria João Brás e masterThesisembargoedAccess
1024-Sep-2015Development and characterization of biopolyelectrolytes functionalized with ionic liquids for transdermal drug delivery applicationsBarroso, Inês Pires Moedas de Almeida masterThesisopenAccess
11Sep-2012Development and characterization of chitosan and N-carboxybutylchitosan materials doped with biocompatible ionic liquids for application as stimuli-responsive biopolymersCortez, Ana Alexandra Rebelo masterThesisopenAccess
125-Nov-2013Development of novel therapeutic approaches for wound healing in diabetesMoura, Liane doctoralThesisopenAccess
1325-Sep-2017Development of ocular implants using a supercritical fluid foaming/ mixing methodologyBizarro, Sara Cristina DuartemasterThesisopenAccess
1418-Nov-2013Dexamethasone-loaded poly(ε-caprolactone)/silica nanoparticles composites prepared by supercritical CO2 foaming/mixing and depositionde Matos, M B C ; Piedade, A P ; Alvarez-Lorenzo, C ; Concheiro, A ; Braga, M E M ; de Sousa, H C articleopenAccess
1526-Sep-2018Dispositivos biomédicos com capacidade melhorada de captura e libertação de oxigénioMarques, Gustavo Filipe Bastos Silva Pinho masterThesisembargoedAccess
1626-Feb-2002Double Critical Phenomena in (Water + Polyacrylamides) SolutionsRebelo, L. P. N. ; Visak, Z. P. ; Sousa, H. C. de ; Szydlowski, J. ; Azevedo, R. Gomes de ; Ramos, A. M. ; Najdanovic-Visak, V. ; Ponte, M. Nunes da ; Klein, J. articleopenAccess
172011Drug loading strategies and processing of polymer blends for intraocular controlled drug release applicationTavares, Mădălina Victoria Natu doctoralThesisopenAccess
18Sep-2012Drug-eluting silica-poly (α-esters) biocomposite materials prepared by green tecnologiesMatos, Maria Betânia Carreira de masterThesisopenAccess
19Sep-2010Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibersNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
202014Effects of Two Phosphonium-Type Ionic Liquids on the Rheological and Thermomechanical Properties of Emulsion Poly(vinyl chloride)-Based Formulations Plasticized with DINP and CITROFOLMarceneiro, Sofia ; Hu, Qingyun ; Dias, Ana M. A. ; Lobo, Irene ; Dias, Isabel ; de Pinho, Elizabete ; Rasteiro, M. Graça ; de Sousa, Hermínio C. articleopenAccess
212011Electrospun Drug-Eluting Fibers for Biomedical ApplicationsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, Maria H. bookPartopenAccess
222020Environmentally-safe scCO2 P. pinaster branches extracts: Composition and propertiesGaspar, Marisa C. ; Sousa, Hermínio C. de ; Seabra, Inês J. ; Braga, Mara E. M. articleembargoedAccess
2314-Sep-2010Estratégias verdes e biométricas para o desenvolvimento de materiais compósitos sílica / biopolímeros / biomoléculas para aplicações biomédicas e de Engenharia de tecidosChim, Rita Joana de Almeida BentomasterThesisopenAccess
2411-May-2006Experimental Determination and Correlation of Artemisinin's Solubility in Supercritical Carbon DioxideCoimbra, Patrícia ; Blanco, Miguel R. ; Silva, Hélio S. R. Costa ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
252010Extraction of valuable compounds from agro-residues of elder (Sambus nigra), pine (Pinus pinaster) and tara (Caesalpinia spinosa)Seabra, Inês José Abrantes de Oliveira doctoralThesisopenAccess
2628-Aug-2008Fractioned High Pressure Extraction of Anthocyanins from Elderberry ( Sambucus nigra L.) PomaceSeabra, Inês J. ; Braga, Mara E. M. ; Batista, Maria T. P. ; Sousa, Hermínio C. de articleopenAccess
2727-Feb-2017Green Methods for the Preparation of Novel Bone Cements Incorporating Highly Porous PCL/SBA-15 Composite BiomaterialsGouveia, João André de Silveira Dias masterThesisopenAccess
282020Impact of the pinewood nematode on naturally-emitted volatiles and scCO2 extracts from Pinus pinaster branches: a comparison with P. pineaGaspar, M. C. ; Agostinho, B.; Fonseca, L.; Abrantes, I. ; Sousa, H. C. de ; Braga, M. E. M. articleembargoedAccess
2915-Feb-2014Impregnation of cinnamaldehyde into cassava starch biocomposite films using supercritical fluid technology for the development of food active packagingde Souza, Ana Cristina ; Dias, Ana M A ; Sousa, Hermínio C ; Tadini, Carmen C articleopenAccess
30Aug-2014Improving cell adhesion: development of a biosensor for cell behaviour monitoring by surface grafting of sulfonic groups onto a thermoplastic polyurethaneAlves, P ; Pinto, S ; Ferreira, P ; Kaiser, Jean-Pierre ; Bruinink, Arie ; de Sousa, Hermínio C ; Gil, M H articleopenAccess
31Jul-2011In vitro and in vivo evaluation of an intraocular implant for glaucoma treatmentNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Cabrita, António M. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
322013Influence of natamycin loading methods on the physical characteristics of alginate active filmsBierhalz, Andrea C.K. ; da Silva, Mariana A. ; de Sousa, Hermínio C. ; Braga, Mara E.M. ; Kieckbusch, Theo G. articleopenAccess
33Jan-2013Influence of polymer processing technique on long term degradation of poly(ε-caprolactone) constructsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. article; preprintopenAccess
3412-Apr-2017Membranas de base PVA mais eficientes para a captura e separação de gasesSousa, Sylvia Fernandes masterThesisembargoedAccess
3526-Jul-2018Nanoparticles-in-thermosensitive enemas as novel rectal anti-HIV microbiocidesMelo, Mélanie Almeida masterThesisembargoedAccess
369-Mar-2018Nanosistemas mais eficientes para terapia fotodinâmicaBuga, Cláudia Sofia Pessa masterThesisembargoedAccess
37Jan-2014Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic miceMoura, Liane I. F. ; Dias, Ana M. A. ; Suesca, Edward ; Casadiegos, Sergio ; Leal, Ermelindo C. ; Fontanilla, Marta R. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
3828-Sep-2018Novos Materiais para a oxigenação melhorada de culturas de células e de scaffolds para Engenharia de TecidosSilva, Mariana Hugo Borges Barreto masterThesisembargoedAccess
3912-Sep-2011On the creation of aquatic inspired adhesive products with polykeetonesSjoerd van, Kuijk masterThesisopenAccess
401-Feb-2015Osteogenic poly(ε-caprolactone)/poloxamine homogeneous blends prepared by supercritical foamingde Matos, Maria B C ; Puga, Ana M ; Alvarez-Lorenzo, Carmen ; Concheiro, Angel ; Braga, Mara E M ; de Sousa, Hermínio C articleopenAccess
4129-Sep-2017Polieletrólitos à base de líquidos iónicos para separação de aminoácidosAntunes, Andreia Sofia Rodrigues masterThesisembargoedAccess
4218-Sep-2013Poly (e-caprolactone)/SBA-15 composite biomaterials plasticized with greener additivesRosa, Antonio Barbosa Soares masterThesisopenAccess
432011A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drugNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Correia, Ilídio J. ; Silva, Daniela ; Sousa, Hermínio C. de ; Gil, M. H. articleclosedAccess
4411-Sep-2015Preparação de compósitos a base de polímeros e sílica mesoporosa para aplicação em engenharia de tecidos duros utilizando a técnica de foaming por tecnologia supercríticaChurro, Rui Miguel Minhós masterThesisopenAccess
457-Dec-2010Preparação e caracterização de sistemas de libertação controlada de fármacos com base em polímeros de origem naturalCoimbra, Patrícia Manuela Almeida doctoralThesisopenAccess
462008Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheresCoimbra, Patrícia A. ; Sousa, Hermínio C. de ; Gil, Maria H. articleopenAccess
4720-Nov-2003Pressure, Isotope, and Water Co-solvent Effects in Liquid−Liquid Equilibria of (Ionic Liquid + Alcohol) SystemsNajdanovic-Visak, Vesna ; Esperança, José M. S. S. ; Rebelo, Luís P. N. ; Ponte, Manuel Nunes da ; Guedes, Henrique J. R. ; Seddon, Kenneth R. ; Sousa, Hermínio C. de ; Szydlowski, Jerzy articleopenAccess
4828-Sep-2018Produção de grafeno por exfoliação de grafite proveniente de elétrodos com recurso a ultrassonsReis, Pedro Miguel Costa Ribeiro dos masterThesisopenAccess
49Jul-2013Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a reviewMoura, Liane I F ; Dias, Ana M A ; Carvalho, Eugénia ; de Sousa, Hermínio C articleopenAccess
5024-Sep-2015Soft contact lenses with improved oxygen capacityPinho, Rui Miguel Abrantes masterThesisembargoedAccess
51Sep-2014A soft lithography method for patterning calcium phosphate ceramicsPereira, Daniel de Melo masterThesisembargoedAccess
5213-Jan-2005Solubility of Acetazolamide in Supercritical Carbon Dioxide in the Presence of Ethanol as a CosolventDuarte, Ana Rita C. ; Santiago, Susana ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
532015Solubility of all-trans retinoic acid in supercritical carbon dioxideRosa, António B.S. ; Marceneiro, Sofia ; Braga, Mara E.M. ; Dias, Ana M.A. ; de Sousa, Hermínio C. articleopenAccess
5414-Aug-2008Solubility of Diflunisal in Supercritical Carbon DioxideCoimbra, Patrícia ; Fernandes, Daniel ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
5513-May-2004Solubility of Flurbiprofen in Supercritical Carbon DioxideDuarte, Ana Rita C. ; Coimbra, Patrícia ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
562008Solubility of Irgacure® 2959 photoinitiator in supercritical carbon dioxide: Experimental determination and correlationCoimbra, Patrícia ; Fernandes, Daniel ; Ferreira, Paula ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
572006Sorption and diffusion of dense carbon dioxide in a biocompatible polymerDuarte, Ana Rita C. ; Martins, Carlos ; Coimbra, Patrícia ; Gil, Maria H. M. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
582007Supercritical fluid impregnation of a biocompatible polymer for ophthalmic drug deliveryDuarte, Ana Rita C. ; Simplicio, Ana Luísa ; Vega-González, Arlette ; Subra-Paternault, Pascale ; Coimbra, Patrícia ; Gil, M. H. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
592008Supercritical solvent impregnation of ophthalmic drugs on chitosan derivativesBraga, Mara E. M. ; Pato, Maria T. Vaz ; Silva, Hélio S. R. Costa ; Ferreira, Elisabeth I. ; Gil, Maria H. ; Duarte, Catarina M. M. ; Sousa, Hermínio C. de articleopenAccess
60Nov-2008Supercritical solvent impregnation of poly(ɛ-caprolactone)/poly(oxyethylene-b-oxypropylene-b-oxyethylene) and poly(ɛ-caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applicationsNatu, Mădălina V. ; Gil, M. H. ; Sousa, Hermínio C. de articleopenAccess
6115-Oct-2013Surface grafting of carboxylic groups onto thermoplastic polyurethanes to reduce cell adhesionAlves, P. ; Ferreira, P. ; Kaiser, Jean-Pierre ; Salk, Natalie ; Bruinink, Arie ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
6223-Sep-2016Synthesis and characterization of ionic liquid based polyampholyte hydrogelsValente, Bárbara Sofia dos Reis masterThesisclosedAccess
632013Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technologyDias, A.M.A. ; Rey-Rico, A. ; Oliveira, R.A. ; Marceneiro, S. ; Alvarez-Lorenzo, C. ; Concheiro, A. ; Júnior, R.N.C. ; Braga, M.E.M. ; de Sousa, H.C. articleopenAccess