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https://hdl.handle.net/10316/3785| Title: | Supercritical fluid impregnation of a biocompatible polymer for ophthalmic drug delivery | Authors: | Duarte, Ana Rita C. Simplicio, Ana Luísa Vega-González, Arlette Subra-Paternault, Pascale Coimbra, Patrícia Gil, M. H. Sousa, Hermínio C. de Duarte, Catarina M. M. |
Keywords: | Supercritical fluids; Impregnation; Biocompatible polymers; Ophthalmic drug delivery | Issue Date: | 2007 | Citation: | The Journal of Supercritical Fluids. 42:3 (2007) 373-377 | Abstract: | Supercritical fluid impregnation was tested to prepare a new ophthalmic drug delivery device. Poly(methylmethacrylate-co-ethylhexylacrylate-co-ethyleneglycoldimethacrylate), P(MMA-EHA-EGDMA) has been proposed by Mariz [M. Mariz, Preparação de uma lente intra-ocular dotada de um sistema de libertação controlada de fármaco, Master Thesis, Universidade de Coimbra, 1999] as a promising matrix to be used for intraocular delivery of anti-inflammatory drugs used in eye surgery. This matrix was successfully impregnated with flurbiprofen, a non-steroidal anti-inflammatory agent. | URI: | https://hdl.handle.net/10316/3785 | DOI: | 10.1016/j.supflu.2007.01.007 | Rights: | openAccess |
| Appears in Collections: | FCTUC Eng.Química - Artigos em Revistas Internacionais |
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| file7c82eb174b5b437c91ba0005cc01215c.pdf | 291.28 kB | Adobe PDF | View/Open |
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