| Issue Date | Title | Author(s) | Type | Access |
| 1 | Dec-2021 | Insulin-degrading enzyme: an ally against metabolic and neurodegenerative diseases | Sousa, Luís; Guarda, Mariana; Meneses, Maria João; Macedo, M. Paula ; Vicente Miranda, Hugo | article | embargoedAccess |
| 2 | 10-Aug-2020 | Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach | Coutinho, Maria Francisca; Santos, Juliana Inês; Mendonça, Liliana ; Matos, Liliana; Prata, Maria João ; Jurado, Amália ; Lima, Maria C. Pedroso de ; Alves, Sandra | article | openAccess |
| 3 | 9-Apr-2020 | Trehalose alleviates the phenotype of Machado-Joseph disease mouse models | Santana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de | article | openAccess |
| 4 | 17-Nov-2020 | Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury | Floriddia, Elisa M.; Lourenço, Tânia ; Zhang, Shupei; van Bruggen, David; Hilscher, Markus M.; Kukanja, Petra; Gonçalves Dos Santos, João P.; Altınkök, Müge; Yokota, Chika; Llorens-Bobadilla, Enric; Mulinyawe, Sara B; Grãos, Mário ; Sun, Lu O.; Frisén, Jonas; Nilsson, Mats; Castelo-Branco, Gonçalo | article | openAccess |
| 5 | 2018 | Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance Test | Matias, Mariana ; Silvestre, Samuel ; Falcão, Amílcar ; Alves, Gilberto | article | openAccess |
| 6 | 5-Nov-2020 | Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons | Silva, Diana F. ; Candeias, Emanuel ; Esteves, Ana Raquel Fernandes ; Magalhães, João Duarte ; Ferreira, I. Luísa ; Nunes-Costa, Daniela ; Rego, Ana Cristina ; Empadinhas, Nuno ; Cardoso, Sandra M. | article | openAccess |
| 7 | Dec-2020 | Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease | Fancellu, Gaia; Chand, Karam; Tomás, Daniel; Orlandini, Elisabetta; Piemontese, Luca; Silva, Diana F. ; Cardoso, Sandra M. ; Chaves, Sílvia; Santos, M. Amélia | article | openAccess |
| 8 | May-2019 | Heartfelt exercise: Physical exercise gets the cardiovascular system into shape | Pereira, Frederico C. | article | openAccess |
| 9 | 2020 | Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention | Cunha-Oliveira, Teresa ; Montezinho, Liliana ; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J. ; Silva, Filomena S. G. | article | openAccess |
| 10 | 2021 | Cell Fate Reprogramming in the Era of Cancer Immunotherapy | Zimmermannova, Olga; Caiado, Inês ; Ferreira, Alexandra G. ; Pereira, Carlos Filipe | article | openAccess |
| 11 | 28-Nov-2020 | An Anthocyanin-Rich Extract Obtained from Portuguese Blueberries Maintains Its Efficacy in Reducing Microglia-Driven Neuroinflammation after Simulated Digestion | Serra, Diana ; Henriques, Joana F. ; Serra, Teresa; Silva, Andreia Bento; Bronze, Maria Rosário; Dinis, Teresa C. P. ; Almeida, Leonor M. | article | openAccess |
| 12 | 14-Oct-2020 | The Coffee-Acrylamide Apparent Paradox: An Example of Why the Health Impact of a Specific Compound in a Complex Mixture Should Not Be Evaluated in Isolation | Nehlig, Astrid; Cunha, Rodrigo A. | article | openAccess |
| 13 | 16-Apr-2020 | Glioblastoma hijacks microglial gene expression to support tumor growth | Maas, Sybren L. N.; Abels, Erik R.; Van De Haar, Lieke L.; Zhang, Xuan; Morsett, Liza; Sil, Srinjoy; Guedes, Joana ; Sen, Pritha; Prabhakar, Shilpa; Hickman, Suzanne E.; Lai, Charles P.; Ting, David T.; Breakefield, Xandra O.; Broekman, Marike L. D.; El Khoury, Joseph | article | openAccess |
| 14 | 2020 | Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System | Oriá, Reinaldo B; Empadinhas, Nuno ; Malva, João O. | article | openAccess |
| 15 | Apr-2021 | Evaluation of the drinking water quality surveillance system in the metropolitan region of Rio de Janeiro | Faria, Clarissa Pérez ; Almendra, Ricardo ; Dias, Gisele Silva; Santana, Paula ; Sousa, Maria do Céu ; Bessa de Freitas, Marcelo | article | openAccess |
| 16 | 2021 | Maternal high-fat high-sucrose diet and gestational exercise modulate hepatic fat accumulation and liver mitochondrial respiratory capacity in mothers and male offspring | Stevanović-Silva, Jelena; Beleza, Jorge; Coxito, Pedro; Pereira, Susana; Rocha, Hugo; Gaspar, Tiago Bordeira; Gärtner, Fátima; Correia, Rossana; Martins, Maria João; Guimarães, Tiago João ; Martins, Sandra Liliana Carvalho ; Oliveira, Paulo J; Ascensão, António ; Magalhães, José | article | openAccess |
| 17 | 1-Oct-2021 | Improving pollutants environmental risk assessment using a multi model toxicity determination with in vitro, bacterial, animal and plant model systems: The case of the herbicide alachlor | Pereira, Susana P; Santos, Sandra M. A. ; Fernandes, Maria A. S. ; Deus, Cláudia M ; Martins, João D ; Pedroso de Lima, Maria C; Vicente, Joaquim A. F. ; Videira, Romeu António ; Jurado, Maria Amália da Silva | article | openAccess |
| 18 | 17-Aug-2021 | Microelectrode Sensor for Real-Time Measurements of Nitrite in the Living Brain, in the Presence of Ascorbate | Monteiro, Tiago; Dias, Cândida ; Lourenço, Cátia F. ; Ledo, Ana ; Barbosa, Rui M. ; Almeida, M. Gabriela | article | openAccess |
| 19 | 25-Jun-2021 | The Alterations of Mitochondrial Function during NAFLD Progression-An Independent Effect of Mitochondrial ROS Production | Simões, Inês C M; Amorim, Ricardo ; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana ; Pereira, Susana P; Simões, Rui F. ; Szymanska, Sylwia; Dąbrowski, Michał; Janikiewicz, Justyna; Dobrzyń, Agnieszka; Oliveira, Paulo J; Potes, Yaiza; Wieckowski, Mariusz R. | article | openAccess |
| 20 | 14-Mar-2021 | Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein | Moreno, Maria João ; Martins, Patricia Alexandra Teles ; Bernardino, Eva F. ; Abel, Biebele; Ambudkar, Suresh V | article | openAccess |
| 21 | 13-Apr-2021 | A selective p53 activator and anticancer agent to improve colorectal cancer therapy | Ramos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A.; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Melo, Teresa M. V. D. Pinho e ; Saraiva, Lucília | article | openAccess |
| 22 | 22-Mar-2021 | Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming | Tawfik, Bassam; Martins, Joana S; Houy, Sébastien; Imig, Cordelia; Pinheiro, Paulo S. ; Wojcik, Sonja M; Brose, Nils; Cooper, Benjamin H; Sørensen, Jakob Balslev | article | openAccess |
| 23 | Jan-2020 | Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism | Almeida, Nuno; Carrara, Guia; Palmeira, Carlos M. ; Fernandes, Ana S.; Parsons, Maddy; Smith, Geoffrey L.; Saraiva, Nuno | article | openAccess |
| 24 | 22-Aug-2018 | Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury | Panisello-Roselló, Arnau; Alva, Norma; Flores, Marta; Lopez, Alexandre ; Castro Benítez, Carlos; Folch-Puy, Emma; Rolo, Anabela ; Palmeira, Carlos ; Adam, René ; Carbonell, Teresa ; Roselló-Catafau, Joan | article | openAccess |
| 25 | 24-Jan-2018 | Cytoprotective Mechanisms in Fatty Liver Preservation against Cold Ischemia Injury: A Comparison between IGL-1 and HTK | Panisello-Roselló, Arnau; Verde, Eva; Lopez, Alexandre ; Flores, Marta; Folch-Puy, Emma; Rolo, Anabela ; Palmeira, Carlos ; Hotter, Georgina; Carbonell, Teresa ; Adam, René ; Roselló-Catafau, Joan | article | openAccess |
| 26 | 19-Jan-2018 | Addition of Berberine to Preservation Solution in an Animal Model of Ex Vivo Liver Transplant Preserves Mitochondrial Function and Bioenergetics from the Damage Induced by Ischemia/Reperfusion | Martins, Rui Miguel; Rolo, Anabela Pinto ; Teodoro, João Soeiro ; Furtado, Emanuel ; Oliveira, Rui Caetano ; Tralhão, José Guilherme ; Palmeira, Carlos Marques | article | openAccess |
| 27 | Dec-2018 | Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid | Teixeira, José ; Oliveira, Catarina; Cagide, Fernando; Amorim, Ricardo ; Garrido, Jorge ; Borges, Fernanda; Oliveira, Paulo J. | article | openAccess |
| 28 | 20-Mar-2018 | MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner | Andriani, Francesca; Majorini, Maria Teresa; Mano, Miguel ; Landoni, Elena; Miceli, Rosalba; Facchinetti, Federica; Mensah, Mavis; Fontanella, Enrico; Dugo, Matteo; Giacca, Mauro; Pastorino, Ugo; Sozzi, Gabriella; Delia, Domenico; Roz, Luca; Lecis, Daniele | article | openAccess |
| 29 | 2018 | MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo | Saraiva, Cláudia; Talhada, Daniela; Rai, Akhilesh ; Ferreira, Raquel; Ferreira, Lino ; Bernardino, Liliana ; Ruscher, Karsten | article | openAccess |
| 30 | 2018 | Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach? | Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. | article | openAccess |
| 31 | May-2018 | Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells | Teixeira, José ; Basit, Farhan; Swarts, Herman G.; Forkink, Marleen; Oliveira, Paulo J. ; Willems, Peter H. G. M.; Koopman, Werner J. H. | article | openAccess |
| 32 | 16-Jul-2018 | The exercise sex gap and the impact of the estrous cycle on exercise performance in mice | Aguiar, Aderbal S. ; Speck, Ana Elisa ; Amaral, Inês M. ; Canas, Paula M. ; Cunha, Rodrigo A. | article | openAccess |
| 33 | 1-Aug-2018 | Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells | Rodrigues, Carlos F. D. ; Serrano, Eurico ; Patrício, Maria I.; Val, Mariana; Albuquerque, Patrícia; Fonseca, João ; Gomes, Célia M. F. ; Abrunhosa, Antero ; Paiva, Artur ; Carvalho, Lina ; Botelho, Maria F. ; Almeida, Luís ; Carreira, Isabel M. ; Alpoim, Maria Carmen | article | openAccess |
| 34 | 12-Jun-2018 | Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease | Duarte, Ana I. ; Sjögren, Marie; Santos, Maria S. ; Oliveira, Catarina R. ; Moreira, Paula I. ; Björkqvist, Maria | article | openAccess |
| 35 | 11-Jan-2018 | Disposition of a Glucose Load into Hepatic Glycogen by Direct and Indirect Pathways in Juvenile Seabass and Seabream | Rito, João ; Viegas, Ivan ; Pardal, Miguel ; Metón, Isidoro ; Baanante, Isabel V. ; Jones, John G. | article | openAccess |
| 36 | Nov-2018 | Secretome of Undifferentiated Neural Progenitor Cells Induces Histological and Motor Improvements in a Rat Model of Parkinson's Disease | Mendes-Pinheiro, Bárbara; Teixeira, Fábio G.; Anjo, Sandra I. ; Manadas, Bruno ; Behie, Leo A.; Salgado, António J. | article | openAccess |
| 37 | Aug-2017 | Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats | Costa, Beatriz Pinto ; Gonçalves, Ana Cristina ; Abrantes, Ana M. ; Matafome, Paulo N. ; Seiça, Raquel ; Ribeiro, Ana Bela Sarmento ; Botelho, Maria Filomena ; Castro-Sousa, Francisco | article | openAccess |
| 38 | 11-Oct-2017 | A transcriptomic approach to study the effect of long-term starvation and diet composition on the expression of mitochondrial oxidative phosphorylation genes in gilthead sea bream (Sparus aurata) | Silva-Marrero, Jonás I; Sáez, Alberto; Caballero-Solares, Albert; Viegas, Ivan ; Almajano, María Pilar; Fernández, Felipe; Baanante, Isabel V. ; Metón, Isidoro | article | openAccess |
| 39 | 2-Oct-2017 | Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells | Oliveira, Ana Isabel; Anjo, Sandra I. ; Vieira de Castro, Joana; Serra, Sofia C.; Salgado, António J. ; Manadas, Bruno ; Costa, Bruno M. | article | openAccess |
| 40 | 5-Oct-2017 | Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage | Boia, Raquel ; Elvas, Filipe ; Madeira, Maria H. ; Aires, Inês D. ; Rodrigues-Neves, Ana C. ; Tralhão, Pedro ; Szabó, Eszter C; Baqi, Younis; Müller, Christa E. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Ambrósio, Francisco ; Santiago, Ana R. | article | openAccess |
| 41 | 5-Dec-2017 | Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2 | Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, Myriam | article | openAccess |
| 42 | 15-Feb-2017 | Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells | Dong, Lan-Feng; Kovarova, Jaromira ; Bajzikova, Martina ; Bezawork-Geleta, Ayenachew ; Svec, David ; Endaya, Berwini ; Sachaphibulkij, Karishma; Coelho, Ana R. ; Sebkova, Natasa; Ruzickova, Anna; Tan, An S; Kluckova, Katarina ; Judasova, Kristyna ; Zamecnikova, Katerina; Rychtarcikova, Zuzana; Gopalan, Vinod; Andera, Ladislav; Sobol, Margarita ; Yan, Bing; Pattnaik, Bijay; Bhatraju, Naveen; Truksa, Jaroslav ; Stopka, Pavel; Hozak, Pavel ; Lam, Alfred K.; Sedlacek, Radislav; Oliveira, Paulo J. ; Kubista, Mikael ; Agrawal, Anurag; Dvorakova-Hortova, Katerina ; Rohlena, Jakub ; Berridge, Michael V. ; Neuzil, Jiri | article | openAccess |
| 43 | 23-Dec-2017 | Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, Munc13-2 and SNAREs | Houy, Sébastien; Groffen, Alexander J; Ziomkiewicz, Iwona; Verhage, Matthijs; Pinheiro, Paulo S. ; Sørensen, Jakob Balslev | article | openAccess |
| 44 | 2017 | The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons | Leal, Graciano ; Comprido, Diogo ; Luca, Pasqualino De ; Morais, Eduardo Manuel Firmo ; Rodrigues, Luís; Mele, Miranda ; Santos, Ana R. ; Costa, Rui O. ; Pinto, Maria Joana ; Patil, Sudarshan; Berentsen, Birgitte; Afonso, Pedro M. ; Carreto, Laura; Li, Ka Wan; Pinheiro, Paulo S. ; Almeida, Ramiro D. ; Santos, Manuel A. S. ; Bramham, Clive R.; Duarte, Carlos B. | article | openAccess |
| 45 | 1-Jul-2017 | Id genes are essential for early heart formation | Cunningham, Thomas J.; Yu, Michael S.; McKeithan, Wesley L.; Spiering, Sean; Carrette, Florent; Huang, Chun-Teng; Bushway, Paul J.; Tierney, Matthew; Albini, Sonia; Giacca, Mauro; Mano, Miguel ; Puri, Pier Lorenzo; Sacco, Alessandra; Ruiz-Lozano, Pilar; Riou, Jean-Francois; Umbhauer, Muriel; Duester, Gregg; Mercola, Mark; Colas, Alexandre R. | article | openAccess |
| 46 | 16-Jan-2018 | Tissular growth factors profile after teduglutide administration on an animal model of intestinal anastomosis | Costa, Beatriz P. ; Gonçalves, Ana C. ; Abrantes, Ana M. ; Alves, Raquel ; Matafome, Paulo N. ; Seiça, Raquel ; Ribeiro, Ana B. Sarmento ; Botelho, M. Filomena ; Castro-Sousa, Francisco | article | openAccess |
| 47 | 2-Mar-2017 | Valorization of Lipids from Gracilaria sp. through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity | Costa, Elisabete da; Melo, Tânia; Moreira, Ana S. P.; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel ; Cruz, Maria Teresa ; Rego, Andreia M.; Domingues, Pedro ; Calado, Ricardo ; Abreu, Maria H.; Domingues, Maria Rosário | article | openAccess |
| 48 | Dec-2017 | First Molecular Characterization of Hypoderma actaeon in Cattle and Red Deer (Cervus elaphus) in Portugal | Ahmed, Haroon; Sousa, Sérgio Ramalho ; Simsek, Sami; Anastácio, Sofia ; Kilinc, Seyma Gunyakti | article | openAccess |
| 49 | 1-Nov-2017 | Lipophilic Fraction of Cultivated Bifurcaria bifurcata R. Ross: Detailed Composition and In Vitro Prospection of Current Challenging Bioactive Properties | Santos, Sónia A. O. ; Trindade, Stephanie S.; Oliveira, Catia S. D.; Parreira, Paula; Rosa, Daniela; Duarte, Maria F.; Ferreira, Isabel ; Cruz, Maria T. ; Rego, Andreia M.; Abreu, Maria H.; Rocha, Sílvia M. ; Silvestre, Armando J. D. | article | openAccess |
| 50 | 2017 | Elevated Glucose and Interleukin-1β Differentially Affect Retinal Microglial Cell Proliferation | Baptista, Filipa I. ; Aveleira, Célia A. ; Castilho, Áurea F. ; Ambrósio, António F. | article | openAccess |
