Cunha-Oliveira, Teresa
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Credit Name
Cunha-Oliveira, Teresa
Name
Cunha-Oliveira, Teresa
Variants
Oliveira, M.T.
Cunha-Oliveira, T.
Oliveira, T.C.
Cunha-Oliveira, T.
Oliveira, T.C.
Email
teresa.oliveira@uc-biotech.pt
Other emails
https://orcid.org/0000-0002-7382-0339
Scopus Author ID
Researcher ID
Status
UC Researcher
Biography
Teresa Cunha-Oliveira got her PhD in Biology (Cell Biology) in 2007 from the University of Coimbra (Portugal), having contributed to introduce the role of mitochondria in the field of drug addiction, particularly concerning cocaine, heroin and amphetamine. In her first post-doctoral period (2007-2010) in the Center for Neuroscience and Cell Biology (CNC, Coimbra), she collaborated with a Medicinal Chemistry group at the University of Porto to uncover the cellular effects of a newly found chemical interaction between heroin and cocaine (speedball) that could have a great impact in the understanding of poly-drug abuse consequences. In her second post-doctoral period (2010-2012), she was focused on the role of mitochondria in neurodegenerative diseases, including Huntington’s disease (HD) and Parkinson’s disease. She became interested in the epigenetic mechanisms associated with long-term mitochondrial dysfunction and contributed to characterize the bioenergetic dysfunction in cybrids from HD patients, evidencing the involvement of pyruvate dehydrogenase (PDH) and the promising role of epigenetic modulators in reversing PDH and mitochondrial dysfunctions in HD models. From 2013 until now, she is part of the MitoXT group at the CNC, more interested in the role of mitochondria in drug toxicology and experimental therapeutics, especially doxorubicin (DOX), an anticancer agent with long-term cardiotoxic side-effects involving mitochondria. She contributed to describe DOX-induced mitochondrial dysfunction, transcriptional deregulation and epigenetic signalling using in vitro and in vivo models. Her current interests include the development and validation of innovative screening assays to assess mitochondrial health with applications in toxicology, diagnostics and development of innovative therapeutic strategies for personalized medicine.
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Publications
(All)
Results 1-51 of 51 (Search time: 0.002 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | Feb-2015 | Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts | Naia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina | article | openAccess |
| 2 | 2013 | Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria | Cunha-Oliveira, Teresa ; Silva, Lisbeth ; Silva, Ana Maria ; Moreno, António J. ; Oliveira, Catarina R. ; Santos, Maria S. | article | openAccess |
| 3 | 2007 | Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine | Cunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 4 | 1-Sep-2017 | Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity | Ferreira, André ; Cunha-Oliveira, Teresa ; Simões, Rui F. ; Carvalho, Filipa S. ; Burgeiro, Ana ; Nordgren, Kendra ; Wallace, Kendall B. ; Oliveira, Paulo J. | article | openAccess |
| 5 | 2015 | Analysis of pro-apoptotic protein trafficking to and from mitochondria | Vega-Naredo, Ignacio ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Sardão, Vilma A. ; Oliveira, Paulo J. | article | openAccess |
| 6 | 2009 | BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons | Almeida, S. ; Laço, M. ; Cunha-Oliveira, T. ; Oliveira, C. R. ; Rego, A. C. | article | openAccess |
| 7 | Nov-2017 | Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts | Coelho, Ana R. ; Martins, Tatiana R. ; Couto, Renata ; Deus, Cláudia ; Pereira, Cláudia V. ; Simões, Rui F. ; Rizvanov, Albert A. ; Silva, Filomena ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. ; Serafim, Teresa L. | article | openAccess |
| 8 | Sep-2011 | Bioenergetic dysfunction in Huntington's disease human cybrids | Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Nascimento, Maria V. ; Ribeiro, Márcio ; Proença, M. Teresa ; Januário, Cristina ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 9 | 2008 | Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs | Cunha-Oliveira, Teresa ; Rego, Ana Cristina ; Oliveira, Catarina R. | article | openAccess |
| 10 | 14-Oct-2023 | Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model | Pereira, Susana P. ; Diniz, Mariana S. ; Tavares, Ludgero C. ; Cunha-Oliveira, Teresa ; Li, Cun; Cox, Laura A ; Nijland, Mark J. ; Nathanielsz, Peter W. ; Oliveira, Paulo J. | article | openAccess |
| 11 | Nov-2021 | Corrigendum to 'A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients'. [Redox Biology 45 (2021) 102037] | Deus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Teixeira, José ; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda; Raimundo, Nuno ; Oliveira, Paulo J. | article | openAccess |
| 12 | 2006 | Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, Maria Teresa ; Macedo, Tice ; Oliveira, Catarina Resende | article | openAccess |
| 13 | 2013 | Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition | Bernardo, Telma C. ; Cunha-Oliveira, Teresa ; Serafim, Teresa L. ; Holy, Jon ; Krasutsky, Dmytro ; Kolomitsyna, Oksana ; Krasutsky, Pavel ; Moreno, A. J. M. ; Oliveira, Paulo J. | article | openAccess |
| 14 | Sep-2012 | Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice | Pereira, Frederico ; Cunha-Oliveira, Teresa ; Viana, Sofia ; Travassos, Ana Sofia ; Nunes, Sara ; Silva, Carlos ; Prediger, Rui ; Rego, Ana Cristina ; Ali, Syed ; Fontes Ribeiro, Carlos Alberto | article | closedAccess |
| 15 | 25-Nov-2019 | Doxorubicin persistently rewires cardiac circadian homeostasis in mice | Ferreira, Luciana L ; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição ; Cunha-Oliveira, Teresa ; Sassone-Corsi, Paolo; Oliveira, Paulo J. | article | embargoedAccess |
| 16 | 2018 | Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes | Cunha-Oliveira, Teresa ; Ferreira, Luciana L ; Coelho, Ana Raquel ; Deus, Cláudia M ; Oliveira, Paulo J | article | openAccess |
| 17 | 2009 | Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF | Almeida, Sandra ; Cunha-Oliveira, Teresa ; Laço, Mário ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 18 | 9-Mar-2012 | Efeito crónico da heroína e do peróxido de hidrogénio em células PC12 | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, M. Teresa ; Macedo, Tice R. ; Oliveira, Catarina R. | article | openAccess |
| 19 | 10-Mar-2022 | Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics | Simões, Rui F. ; Oliveira, Paulo J. ; Oliveira, Teresa Cunha ; Pereira, Francisco B. | article | openAccess |
| 20 | 8-Mar-2012 | Expression of NR1/NR2B N-Methyl-d-Aspartate Receptors Enhances Heroin Toxicity in HEK293 Cells | Domingues, António ; Cunha-Oliveira, Teresa ; Laço, Mário L. N. ; Macedo, Tice ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 21 | 15-Nov-2012 | Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells | Ribeiro, Márcio ; Rosenstock, Tatiana ; Cunha-Oliveira, Teresa ; Ferreira, Ildete ; Oliveira, Catarina R. ; Rego, Ana Cristina | article | openAccess |
| 22 | 2005 | Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis | Cunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 23 | Aug-2018 | Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells | Abreu, Patrícia L. ; Cunha-Oliveira, Teresa ; Ferreira, Leonardo M R ; Urbano, Ana M. | article | openAccess |
| 24 | 8-Mar-2017 | Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease | Naia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina | article | openAccess |
| 25 | 3-Oct-2019 | Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress | Ferreira, Leonardo M. R. ; Cunha-Oliveira, Teresa ; Sobral, Margarida C. ; Abreu, Patrícia L. ; Alpoim, Maria Carmen ; Urbano, Ana M. | article | openAccess |
| 26 | 18-Sep-2019 | Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease | Valdinocci, Dario; Simões, Rui F. ; Kovarova, Jaromira ; Cunha-Oliveira, Teresa ; Neuzil, Jiri ; Pountney, Dean L | article | openAccess |
| 27 | Aug-2016 | Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity | Silva, Ana Marta ; Barbosa, Inês A. ; Seabra, Cátia ; Beltrão, Nuno ; Santos, Raquel ; Vega-Naredo, Ignacio ; Oliveira, Paulo ; Cunha-Oliveira, Teresa | article | openAccess |
| 28 | Mar-2016 | Ketogenic diets: from cancer to mitochondrial diseases and beyond | Branco, Ana F. ; Ferreira, André ; Simões, Rui F. ; Magalhães-Novais, Sílvia ; Zehowski, Cheryl ; Cope, Elisabeth ; Silva, Ana Marta ; Pereira, Daniela ; Sardão, Vilma A. ; Cunha-Oliveira, Teresa | article | openAccess |
| 29 | 1-Jul-2018 | Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity | Pereira, Susana P. ; Deus, Cláudia M. ; Serafim, Teresa L. ; Cunha-Oliveira, Teresa ; Oliveira, Paulo J. | article | openAccess |
| 30 | 10-May-2023 | Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics | Pinho, Sónia A. ; Anjo, Sandra I. ; Cunha-Oliveira, Teresa | article | openAccess |
| 31 | 16-Jul-2022 | Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems | Amorim, Ricardo ; Simões, Inês C. M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana ; Tavares, Ludgero C. ; Benfeito, Sofia; Pereira, Susana P.; Simões, Rui F. ; Karkucinska-Wieckowska, Agnieszka; Viegas, Ivan ; Szymanska, Sylwia; Dąbrowski, Michał; Janikiewicz, Justyna; Cunha-Oliveira, Teresa ; Dobrzyń, Agnieszka; Jones, John Griffith ; Borges, Fernanda; Wieckowski, Mariusz R. ; Oliveira, Paulo J. | article | openAccess |
| 32 | 2021 | A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients | Deus, Cláudia M. ; Pereira, Susana P.; Cunha-Oliveira, Teresa ; Teixeira, José; Simões, Rui F. ; Cagide, Fernando; Benfeito, Sofia; Borges, Fernanda; Raimundo, Nuno ; Oliveira, Paulo J. | article | openAccess |
| 33 | Dec-2014 | Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts | Moreira, Ana C. ; Branco, Ana F. ; Sampaio, Susana F. ; Cunha-Oliveira, Teresa ; Martins, Tatiana R. ; Holy, Jon ; Oliveira, Paulo J. ; Sardão, Vilma A. | article | openAccess |
| 34 | 1-May-2013 | Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria | Cunha-Oliveira, Teresa ; Silva, Lisbeth ; Silva, Ana Maria ; Moreno, António J. ; Oliveira, Catarina R. ; Santos, Maria S. | article | openAccess |
| 35 | 2006 | Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine | Cunha-Oliveira, T. ; Rego, A. C. ; Cardoso, S. M. ; Borges, F. ; Swerdlow, R. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 36 | 2020 | Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects | Deus, Cláudia M. ; Pereira, Susana P. ; Cunha-Oliveira, Teresa ; Pereira, Francisco B. ; Raimundo, Nuno Filipe Viegas das Neves ; Oliveira, Paulo J. | article | embargoedAccess |
| 37 | 2021 | MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile | Jacinto, Sandra; Guerreiro, Patrícia; Oliveira, Rita Machado de; Oliveira, Teresa Cunha ; Santos, Maria João ; Grazina, Manuela ; Rego, A. Cristina ; Outeiro, Tiago F. | article | openAccess |
| 38 | 8-Mar-2012 | Neurotoxicity of heroin-cocaine combinations in rat cortical neurons | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina R. | article | openAccess |
| 39 | 28-Aug-2014 | Oxidative Stress and Drugs of Abuse: An Update | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. | article | openAccess |
| 40 | 2020 | Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention | Cunha-Oliveira, Teresa ; Montezinho, Liliana ; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J. ; Silva, Filomena S. G. | article | openAccess |
| 41 | 2021 | Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine | Simões, Rui F. ; Pino, Rute; Soares, Maurício Moreira ; Kovarova, Jaromira ; Neuzil, Jiri ; Travasso, Rui ; Oliveira, Paulo J.; Cunha-Oliveira, Teresa ; Pereira, Francisco B. | article | openAccess |
| 42 | 5-Feb-2019 | Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells | Bajzikova, Martina ; Kovarova, Jaromira ; Coelho, Ana R. ; Boukalova, Stepana ; Oh, Sehyun ; Rohlenova, Katerina ; Svec, David ; Hubackova, Sona ; Endaya, Berwini ; Judasova, Kristyna ; Bezawork-Geleta, Ayenachew ; Kluckova, Katarina ; Chatre, Laurent ; Zobalova, Renata ; Novakova, Anna ; Vanova, Katerina ; Ezrova, Zuzana ; Maghzal, Ghassan J ; Magalhaes Novais, Silvia ; Olsinova, Marie ; Krobova, Linda ; An, Yong Jin ; Davidova, Eliska ; Nahacka, Zuzana ; Sobol, Margarita ; Cunha-Oliveira, Teresa ; Sandoval-Acuña, Cristian ; Strnad, Hynek ; Zhang, Tongchuan ; Huynh, Thanh ; Serafim, Teresa L. ; Hozak, Pavel ; Sardão, Vilma A. ; Koopman, Werner J H ; Ricchetti, Miria ; Oliveira, Paulo J ; Kolar, Frantisek ; Kubista, Mikael ; Truksa, Jaroslav ; Dvorakova-Hortova, Katerina ; Pacak, Karel ; Gurlich, Robert ; Stocker, Roland ; Zhou, Yaoqi ; Berridge, Michael V ; Park, Sunghyouk ; Dong, Lanfeng ; Rohlena, Jakub ; Neuzil, Jiri | article | embargoedAccess |
| 43 | Sep-2013 | Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 44 | 1-Nov-2012 | Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 45 | 2017 | Role of Mitochondria on the Neurological Effects of Cocaine | Pereira, S.P. ; Cunha-Oliveira, T. | article | openAccess |
| 46 | Jan-2015 | Role of mtDNA-related mitoepigenetic phenomena in cancer | Ferreira, André ; Serafim, Teresa L. ; Sardão, Vilma A. ; Cunha-Oliveira, Teresa | article | openAccess |
| 47 | 14-May-2021 | Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction | Pereira, Susana P. ; Tavares, Ludgero C. ; Duarte, Ana I. ; Baldeiras, Inês ; Cunha-Oliveira, Teresa ; Martins, João D. ; Santos, Maria S. ; Maloyan, Alina; Moreno, Antonio J. ; Cox, Laura A. ; Li, Cun; Nathanielsz, Peter W. ; Nijland, Mark J. ; Oliveira, Paulo J. | article | embargoedAccess |
| 48 | Feb-2019 | Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts | Ferreira, Luciana L. ; Cunha-Oliveira, Teresa ; Veloso, Caroline D. ; Costa, Cláudio F. ; Wallace, Kendall B. ; Oliveira, Paulo J. | article | embargoedAccess |
| 49 | 2007 | Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina Resende | article | openAccess |
| 50 | Oct-2006 | Synthesis and Cytotoxic Profile of 3,4-Methylenedioxymethamphetamine (“Ecstasy”) and Its Metabolites on Undifferentiated PC12 Cells: A Putative Structure−Toxicity Relationship | Milhazes, Nuno ; Cunha-Oliveira, Teresa ; Martins, Pedro ; Garrido, Jorge ; Oliveira, Catarina ; Rego, A. Cristina ; Borges, Fernanda | article | openAccess |
| 51 | 2014 | β-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates? | Branco, Ana F. ; Moreira, Ana C. ; Cunha-Oliveira, Teresa ; Couto, Renata ; Sardão, Vilma A. ; Rizvanov, Albert A. ; Palotas, Andras ; Oliveira, Paulo J. | article | openAccess |