Ferreira, Lino

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Credit Name
Ferreira, Lino
 
Name
Ferreira, Lino
 
Unidade de I&D
 
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Researcher ID
 
Status
UC Researcher
Biography
I did my graduate work in Jonathan Dordick´s lab at Rensselaer Polytechnic Institute (RPI, Albany, NY) in the development of carbohydrate-based hydrogels, chemically crosslinked, using nonaqueous enzyme technology. I did a first postdoc at the Institute of Biomedical Engineering (Porto, Portugal) for 1 year, specifically at the laboratory of Mário Barbosa (2001 George Winter Award from the European Society of Biomaterials). During that time, I contributed for the development of an intervertebral disc prosthesis. I started in the end of 2004 a second postdoc at MIT in the laboratory of Robert Langer (2002 Charles Stark Draper Prize). The major contributions of my postdoc work was to isolate vascular progenitor cells from human embryonic stem cells (hESCs), to develop synthetic stem cell niches for the self-renewal and vascular differentiation of hESCs, nanomaterials for cell tracking, elastomeric materials, antifungal hydrogels and Gecko-inspired medical adhesives. When I started my laboratory at CNC, University of Coimbra, in October 2007, I established the field of Biomaterials and Stem Cell-Based Therapeutics within the institution. Presently, 29 researchers including 2 Senior Researcher, 10 Postdocs, 8 PhD students, 6 Technicians and 3 Master students form the research group. The research work has been published in Nature Methods, Nature Protocols, Science Translational Medicine, Nature Communications, PNAS, ACS nano, Advanced Materials and Cell Stem Cell. My independent work has been distinguished with several awards in international meetings and with the Crioestaminal Prize, in recognition of the best biomedical basic research project carried out in Portugal in 2008, an ERC grant in 2012 and a ERA Chair grant in 2016. In the last 10 years I attracted around 10 million euros in grants.
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Publications
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Refined By:
Date Issued:  [2010 TO 2020]
Author:  Ferreira, L.

Results 1-39 of 39 (Search time: 1.007 seconds).

Issue DateTitleAuthor(s)TypeAccess
126-Aug-2020Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicineFerreira, Raquel; Napoli, Joseph; Enver, Tariq; Bernardino, Liliana ; Ferreira, Lino articleopenAccess
22017Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded NanoparticlesMachado-Pereira, Marta; Santos, Tiago ; Ferreira, Lino ; Bernardino, Liliana ; Ferreira, RaquelarticleopenAccess
328-Sep-2017Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potentialComune, Michela ; Rai, Akhilesh ; Chereddy, Kiran K; Pinto, Sandra; Aday, Sezin; Ferreira, André F; Zonari, Alessandra ; Blersch, Josephine; Cunha, Rodrigo Pinto Antunes da ; Rodrigues, Ricardo; Lerma, Juan ; Simões, Pedro Nuno ; Préat, Veronique; Ferreira, Lino articleopenAccess
423-Jul-2018Author Correction: Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulationLima, A.; May, G.; Díaz-Colunga, J.; Pedreiro, S.; Paiva, A. ; Ferreira, L. ; Enver, T.; Iborra, F. J.; Neves, R. Pires das articleopenAccess
5Sep-2017Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticlesSantos, Tiago ; Ferreira, Raquel ; Quartin, Emanuel ; Boto, Carlos ; Saraiva, Cláudia ; Bragança, José ; Peça, João ; Rodrigues, Cecília ; Ferreira, Lino ; Bernardino, Liliana articleopenAccess
62013Boron nitride nanotube-mediated stimulation of cell co-culture on micro-engineered hydrogelsRicotti, Leonardo; Fujie, Toshinori; Vazão, Helena ; Ciofani, Gianni; Marotta, Roberto; Brescia, Rosaria; Filippeschi, Carlo; Corradini, Irene; Matteoli, Michela; Mattoli, Virgilio; Ferreira, Lino ; Menciassi, AriannaarticleopenAccess
74-Dec-2018Cooperative Transcription Factor Induction Mediates Hemogenic ReprogrammingGomes, Andreia ; Kurochkin, Ilia; Chang, Betty; Daniel, Michael; Law, Kenneth; Satija, Namita; Lachmann, Alexander; Wang, Zichen; Ferreira, Lino ; Ma'ayan, Avi; Chen, Benjamin K.; Papatsenko, Dmitri; Lemischka, Ihor R; Moore, Kateri A.; Pereira, Carlos Filipe articleopenAccess
82019Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor CellsPraça, Catarina ; Rosa, Susana C. ; Sevin, Emmanuel; Cecchelli, Romeo; Dehouck, Marie-Pierre ; Ferreira, Lino S. articleopenAccess
918-Feb-2016Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylationBlondel, S.; Egesipe, A-L; Picardi, P.; Jaskowiak, A-L; Notarnicola, M.; Ragot, J.; Tournois, J.; Le Corf, A.; Brinon, B.; Poydenot, P.; Georges, P.; Navarro, C.; Pitrez, P. R. ; Ferreira, L. ; Bollot, G.; Bauvais, C.; Laustriat, D.; Mejat, A.; De Sandre-Giovannoli, A.; Levy, N.; Bifulco, M.; Peschanski, M.; Nissan, X.articleopenAccess
102017Erratum: Restoring heart function and electrical integrity: Closing the circuitMonteiro, Luís Miguel ; Vasques-Nóvoa, Francisco; Ferreira, Lino ; Pinto-do-Ó, Perpétua; Nascimento, Diana SantosarticleopenAccess
117-Mar-2019Functional characterization of iPSC-derived arterial- and venous-like endothelial cellsRosa, Susana ; Praça, Catarina ; Pitrez, Patrícia ; Gouveia, Pedro ; Xabier, Aranguren ; Leonardo, Ricotti ; Ferreira, Lino articleopenAccess
1221-Dec-2020A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapiesFrancisco, Vitor ; Rebelo, Catarina; Rodrigues, Artur Filipe ; Blersch, Catarina; Fernandes, Hugo ; Ferreira, Lino articleopenAccess
138-May-2012Histamine modulates microglia functionFerreira, Raquel ; Santos, Tiago ; Gonçalves, Joana ; Baltazar, Graça ; Ferreira, Lino ; Agasse, Fabienne ; Bernardino, Liliana articleopenAccess
14Jan-2011Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-Cultured with Endothelial CellsPedroso, Dora C. S. ; Tellechea, Ana ; Moura, Liane ; Fidalgo-Carvalho, Isabel ; Duarte, João ; Carvalho, Eugénia ; Ferreira, Lino articleopenAccess
152017Intracellular delivery of more than one protein with spatio-temporal controlLino, Miguel M. ; Simões, Susana ; Pinho, Sónia ; Ferreira, Lino articleopenAccess
1621-Apr-2020A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1α (HIF-1α)Blersch, Josephine; Francisco, Vitor ; Rebelo, Catarina; Jiménez-Balsa, Adrián ; Antunes, Helena; Pinto, Sandra; Simões, Susana ; Rai, Akhilesh ; Ferreira, Lino articleopenAccess
1723-May-2018Light-triggerable formulations for the intracellular controlled release of biomoleculesLino, Miguel ; Ferreira, Lino articleopenAccess
1810-Nov-2015Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditionsKostic, Ivana; Fidalgo-Carvalho, Isabel ; Aday, Sezin; Vazão, Helena ; Carvalheiro, Tiago; Grãos, Mário ; Duarte, António; Cardoso, Carla; Gonçalves, Lino ; Carvalho, Lina ; Paiva, Artur ; Ferreira, Lino articleopenAccess
192018MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivoSaraiva, Cláudia; Talhada, Daniela; Rai, Akhilesh ; Ferreira, Raquel; Ferreira, Lino ; Bernardino, Liliana ; Ruscher, Karsten articleopenAccess
205-Jun-2018Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded NanocarriersLino, Miguel M. ; Simões, Susana ; Vilaça, Andreia ; Antunes, Helena ; Zonari, Alessandra ; Ferreira, Lino articleopenAccess
212018A nanoformulation for the preferential accumulation in adult neurogenic nichesPraça, Catarina ; Rai, Akhilesh ; Santos, Tiago ; Cristovão, Ana C.; Pinho, Sonia L.; Cecchelli, Romeo; Dehouck, Marie-Pierre ; Bernardino, Liliana Inácio ; Ferreira, Lino S. articleopenAccess
2213-Apr-2018Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of BiomoleculesJiménez-Balsa, Adrián ; Pinto, Sandra ; Quartin, Emanuel ; Lino, Miguel M. ; Francisco, Vitor ; Ferreira, Lino articleopenAccess
231-Jun-2020Native and engineered extracellular vesicles for cardiovascular therapeuticsAbreu, Ricardo Cerqueira de ; Fernandes, Hugo ; Martins, Paula Costa; Sahoo, Susmita; Emanueli, Costanza; Ferreira, Lino articleopenAccess
2416-Sep-2019A near infrared light-triggerable modular formulation for the delivery of small biomoleculesFrancisco, Vitor ; Lino, Miguel ; Ferreira, Lino articleopenAccess
258-May-2018Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulationLima, A. ; May, G.; Díaz-Colunga, J.; Pedreiro, S.; Paiva, A. ; Ferreira, L. ; Enver, T.; Iborra, F. J.; Neves, R. Pires das articleopenAccess
2618-Sep-2020Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic reviewBernardo-Castro, Sara; Donato, Helena ; Ferreira, Lino ; Sargento-Freitas, João articleopenAccess
272018Physiological and Pathological Vascular AgingPitrez, Patrícia R. ; Aires, Helena R.; Tomé, Inês; Ferreira, Rita Sá; Ferreira, Lino bookopenAccess
2819-Jun-2019A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesiclesBanerjee, Arnab; Alves, Vitor; Rondão, Tiago; Sereno, José; Neves, Ângela; Lino, Miguel ; Ribeiro, Andreia; Abrunhosa, Antero ; Ferreira, Lino articleembargoedAccess
2911-May-2017Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activationBoto, Carlos ; Quartin, Emanuel ; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra ; Gupta, Rajeev; Enver, Tariq; Sánchez-García, Isidro; Hong, Dengli; Neves, Ricardo Pires das ; Ferreira, Lino articleopenAccess
302017Restoring heart function and electrical integrity: closing the circuitMonteiro, Luís Miguel ; Vasques-Nóvoa, Francisco; Ferreira, Lino ; Pinto-do-Ó, Perpétua; Nascimento, Diana SantosarticleopenAccess
312015Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's diseaseEsteves, Marta ; Cristóvão, Ana C.; Saraiva, Tatiana; Rocha, Sandra M.; Baltazar, Graça ; Ferreira, L. ; Bernardino, Liliana articleopenAccess
322014A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cellsCecchelli, Romeo; Aday, Sezin; Sevin, Emmanuel; Almeida, Catarina ; Culot, Maxime; Dehouck, Lucie; Coisne, Caroline; Engelhardt, Britta; Dehouck, Marie-Pierre ; Ferreira, Lino articleopenAccess
332018Stem cells as vehicles and targets of nanoparticlesPinho, Sónia ; Macedo, Maria H; Rebelo, Catarina Araujo Gomes ; Sarmento, Bruno ; Ferreira, Lino articleopenAccess
342018Substrate Topography Modulates Cell Aging on a Progeria Cell ModelPitrez, Patrícia R. ; Estronca, Luís Miguel Beicinha Branco ; Vazão, Helena ; Egesipe, Anne-Laure; Le Corf, Amélie; Navarro, Claire; Lévy, Nicolas ; De Sandre-Giovannoli, Annachiara; Nissan, Xavier; Ferreira, Lino articleopenAccess
352017Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibitionAday, Sezin; Zoldan, Janet; Besnier, Marie; Carreto, Laura; Saif, Jaimy; Fernandes, Rui; Santos, Tiago ; Bernardino, Liliana Inácio ; Langer, Robert ; Emanueli, Costanza; Ferreira, Lino articleopenAccess
367-Aug-2019The Kinetics of Small Extracellular Vesicle Delivery Impacts Tissue RegenerationAntunes, Helena; Cardoso, Renato ; Zonari, Alessandra ; Correia, Joana; Leal, Ermelindo ; Jiménez-Balsa, Adrián ; Lino, Miguel ; Barradas, Ana; Kostic, Ivana; Gomes, Célia ; Karp, Jeffrey; Carvalho, Eugénia ; Ferreira, Lino articleopenAccess
3710-Mar-2011Towards the Maturation and Characterization of Smooth Muscle Cells Derived from Human Embryonic Stem CellsVazão, Helena ; Neves, Ricardo Pires das ; Grãos, Mário ; Ferreira, Lino articleopenAccess
382020Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13Pitrez, Patrícia R. ; Estronca, Luís Miguel Beicinha Branco ; Monteiro, Luís Miguel Marques ; Colell, Guillem; Vazão, Helena ; Santinha, Deolinda da Conceição Ribafeita ; Harhouri, Karim; Thornton, Daniel; Navarro, Claire; Egesipe, Anne-Laure; Carvalho, Tania Rafaela Vale ; Santos, Rodrigo L. dos; Lévy, Nicolas ; Smith, James C.; Magalhães, João Pedro de; Ori, Alessandro; Bernardo, Andreia; De Sandre-Giovannoli, Annachiara; Nissan, Xavier; Rosell, Anna; Ferreira, Lino articleopenAccess
392019What human blood-brain barrier models can tell us about BBB function and drug discovery?Ferreira, Lino articleopenAccess