Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/92397
Title: Stem cells as vehicles and targets of nanoparticles
Authors: Pinho, Sónia 
Macedo, Maria H
Rebelo, Catarina Araujo Gomes 
Sarmento, Bruno 
Ferreira, Lino 
Issue Date: 2018
Publisher: Elsevier
Serial title, monograph or event: Drug Discovery Today
Volume: 23
Issue: 5
Abstract: Modulation of endogenous adult stem cell niches represents a promising strategy for regeneration of tissues and to correct cell abnormalities, including cancer. Recent advances show the possibility to target endogenous stem cells or their progenies by using nanoparticles conjugated with specific biomolecules. In addition, the targeting of the stem cell niche can be accomplished by using stem cells loaded with nanoparticles. This review examines principles for the targeting of endogenous stem cells as well as factors for the modulation of stem cells.
URI: https://hdl.handle.net/10316/92397
ISSN: 13596446
DOI: 10.1016/j.drudis.2018.01.030
Rights: openAccess
Appears in Collections:FMUC Medicina - Artigos em Revistas Internacionais

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