Search: CNC - Centro de Neurociências e Biologia Celular
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| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2022 | Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease | Miranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de | article | openAccess |
| 2 | 2020 | Mesenchymal Stromal Cells' Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go? | Barros, Inês ; Marcelo, Adriana ; Silva, Teresa P. ; Barata, João ; Ramos, António David Rufino ; Almeida, Luís P. de ; Miranda, Catarina O. | article | openAccess |
| 3 | 7-Jul-2020 | Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice | Wilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, Matthis | article | openAccess |
| 4 | 8-Feb-2021 | Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease | Duarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de | article | openAccess |
| 5 | 31-Aug-2020 | The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples | Duarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de | article | openAccess |
| 6 | 2019 | Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia | Nóbrega, Clévio David Rodrigues ; Mendonça, Liliana Simões ; Marcelo, Adriana Isabel do Vale ; Lamazière, Antonin; Tomé, Sandra Marisa Oliveira ; Despres, Gaetan; Matos, Carlos A; Mechmet, Fatich; Langui, Dominique; den Dunnen, Wilfred; Almeida, Luís Pereira de ; Cartier, Nathalie; Alves, Sandro José Paiva Fernandes | article | embargoedAccess |
| 7 | Mar-2018 | Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice | Marques, Ana Patrícia; Cunha-Santos, Janete; Leal, Helena; Sousa-Ferreira, Lígia ; Pereira de Almeida, Luís ; Cavadas, Cláudia ; Rosmaninho-Salgado, Joana | article | openAccess |
| 8 | 2012 | Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease | Simões, Ana T. ; Gonçalves, Nélio ; Koeppen, Arnulf ; Déglon, Nicole ; Kügler, Sebastian ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de | article | openAccess |
| 9 | 5-Mar-2014 | Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro | Sousa-Ferreira, Lígia ; Aveleira, Célia ; Botelho, Mariana ; Álvaro, Ana Rita ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 10 | 2013 | Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph disease | Gonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de | article | openAccess |
| 11 | 1-Jun-2011 | Effect of Food on the Pharmacokinetic Profile of Etamicastat (BIA 5-453) | Vaz-da-Silva, Manuel ; Nunes, Teresa ; Rocha, José F. ; Falcão, Amílcar ; Almeida, Luis ; Soares-da-Silva, Patricio | article | openAccess |
| 12 | 7-Jul-2021 | Living Proof of Activity of Extracellular Vesicles in the Central Nervous System | Mahjoum, Shadi; Rufino-Ramos, David; Almeida, Luís Pereira de ; Broekman, Marike L. D.; Breakefield, Xandra O.; van Solinge, Thomas S. | article | openAccess |
| 13 | 2014 | Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph disease | Simões, Ana Teresa ; Gonçalves, Nélio ; Nobre, Rui Jorge ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de | article | embargoedAccess |
| 14 | 21-Aug-2014 | RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph Disease | Nóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Déglon, Nicole ; Almeida, Luís Pereira de | article | openAccess |
| 15 | 2021 | Highly Porous Composite Scaffolds Endowed with Antibacterial Activity for Multifunctional Grafts in Bone Repair | Neto, Ana S.; Pereira, Patrícia ; Fonseca, Ana C. ; Dias, Carla ; Almeida, Mariana C. ; Barros, Inês ; Miranda, Catarina O. ; Almeida, Luís P. de ; Morais, Paula V. ; Ferreira, José M. F. | article | openAccess |
| 16 | 2-Oct-2021 | Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening | Aguiar, Sandra Isabel; Dias, Joana N. R.; André, Ana Santos; Silva, Marta Lisete; Martins, Diana; Carrapiço, Belmira; Castanho, Miguel A. R. B. ; Carriço, João; Cavaco, Marco; Gaspar, Maria Manuela; Nobre, Rui J. ; Almeida, Luís Pereira de ; Oliveira, Soraia; Gano, Lurdes; Correia, João D. G.; Barbas, Carlos; Gonçalves, João; Neves, Vera; Aires-da-Silva, Frederico | article | openAccess |
| 17 | 2019 | Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation | Henrique, Daniel ; Moreira, Ricardo ; Schwamborn, Jens; Almeida, Luís Pereira de ; Mendonça, Liliana | article | openAccess |
| 18 | 14-May-2019 | Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality | Walter, Jonas; Bolognin, Silvia; Antony, Paul M. A.; Nickels, Sarah L.; Poovathingal, Suresh K.; Salamanca, Luis; Magni, Stefano; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Almeida, Luís Pereira de ; Skupin, Alexander; Tronstad, Karl J.; Schwamborn, Jens C. | article | openAccess |
| 19 | 25-Aug-2021 | The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado-Joseph disease | Vasconcelos-Ferreira, Ana ; Carmo-Silva, Sara; Codêsso, José Miguel Antunes ; Silva, Patrick Joel da ; Martinez, Alberto Rolim Muro; França, Marcondes Cavalcante; Nóbrega, Clévio David Rodrigues ; Almeida, Luís Pereira de | article | embargoedAccess |
| 20 | 29-Nov-2021 | Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy | Marcelo, Adriana ; Afonso, Inês T.; Afonso-Reis, Ricardo; Brito, David V. C.; Costa, Rafael G.; Rosa, Ana; Alves-Cruzeiro, João ; Ferreira, Benedita; Henriques, Carina; Nobre, Rui J. ; Matos, Carlos A.; Almeida, Luís Pereira de ; Nóbrega, Clévio | article | openAccess |
| 21 | 13-Nov-2021 | Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases | Moreira, Ricardo ; Mendonça, Liliana Simões ; Almeida, Luís Pereira de | article | openAccess |
| 22 | 2016 | Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation | Ferreira-Marques, Marisa; Aveleira, Célia A. ; Carmo-Silva, Sara; Botelho, Mariana ; Pereira de Almeida, Luís ; Cavadas, Cláudia | article | openAccess |
| 23 | 19-Oct-2021 | The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 | Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh K.; Magni, Stefano; Gérard, Deborah; Antony, Paul M. A.; Nickels, Sarah L.; Salamanca, Luis; Berger, Emanuel; Smits, Lisa M.; Grzyb, Kamil; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michèle; Almeida, Luís Pereira de ; Tronstad, Karl J.; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens C. | article | openAccess |
| 24 | 11-Sep-2020 | Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research | Gaspar, Laetitia da Silva ; Santana, Magda M. ; Henriques, Carina ; Pinto, Maria M. ; Ribeiro-Rodrigues, Teresa M. ; Girão, Henrique ; Nobre, Rui Jorge ; Almeida, Luís Pereira de | article | openAccess |
| 25 | 8-Jun-2021 | Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation? | Marcelo, Adriana ; Koppenol, Rebekah; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio | article | openAccess |
| 26 | 2020 | Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting | Lopes, Carla ; Tang, Yang; Anjo, Sandra I. ; Manadas, Bruno ; Onofre, Isabel ; Almeida, Luís P. de ; Daley, George Q; Schlaeger, Thorsten M; Rego, Ana Cristina Carvalho | article | openAccess |
| 27 | 9-Apr-2020 | Trehalose alleviates the phenotype of Machado-Joseph disease mouse models | Santana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de | article | openAccess |
| 28 | 6-Mar-2020 | miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's Disease | Barros-Viegas, Ana Teresa ; Carmona, Vitor ; Ferreiro, Elisabete ; Guedes, Joana ; Cardoso, Ana Maria S. ; Cunha, Pedro ; Almeida, Luís Pereira de ; Oliveira, Catarina Resende de ; Magalhães, João Pedro de ; Peça, João ; Cardoso, Ana Luísa | article | openAccess |
| 29 | 2017 | Generation of human iPSC line from a patient with laterality defects and associated congenital heart anomalies carrying a DAND5 missense alteration | Cristo, Fernando; Inácio, José M; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Almeida, Luís Pereira de ; Mendes, Patrícia; Martins, Duarte Saraiva; Maio, José; Anjos, Rui ; Belo, José A. | article | openAccess |
| 30 | 1-Aug-2018 | Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells | Rodrigues, Carlos F. D. ; Serrano, Eurico ; Patrício, Maria I.; Val, Mariana; Albuquerque, Patrícia; Fonseca, João ; Gomes, Célia M. F. ; Abrunhosa, Antero ; Paiva, Artur ; Carvalho, Lina ; Botelho, Maria F. ; Almeida, Luís ; Carreira, Isabel M. ; Alpoim, Maria Carmen | article | openAccess |
| 31 | May-2018 | Generation and characterization of a human iPS cell line from a patient-related control to study disease mechanisms associated with DAND5 p.R152H alteration | Pars, Selin; Cristo, Fernando; Inácio, José M.; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Mendes, Patrícia; Martins, Duarte Saraiva; Almeida, Luís Pereira de ; Maio, José; Anjos, Rui ; Belo, José A. | article | openAccess |
| 32 | 5-Dec-2017 | Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2 | Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, Myriam | article | openAccess |
| 33 | Mar-2016 | Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles | Conceição, Mariana ; Mendonça, Liliana ; Nóbrega, Clévio; Gomes, Célia ; Costa, Pedro ; Hirai, Hirokazu; Moreira, João Nuno ; Lima, Maria C. Pedroso de ; Manjunath, N.; Almeida, Luís Pereira de | article | openAccess |
| 34 | 2016 | Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review | Alves-Cruzeiro, João M. da Conceição ; Mendonça, Liliana ; Almeida, Luís Pereira de | article | openAccess |
| 35 | 11-May-2016 | Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway | Cunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 36 | 22-Jun-2016 | Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment | Onofre, Isabel ; Mendonça, Nuno ; Lopes, Sara ; Nobre, Rui J. ; Melo, Joana Barbosa ; Carreira, Isabel Marques ; Januário, Cristina ; Gonçalves, António Freire ; Almeida, Luís Pereira de | article | openAccess |
| 37 | 2013 | Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice | Nóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de | article | openAccess |
| 38 | 2011 | Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats | Sousa-Ferreira, Lígia ; Garrido, Manuel Joaquim Marques ; Nascimento-Ferreira, Isabel ; Nóbrega, Clévio ; Carvalho, Ana dos Santos ; Álvaro, Ana Rita Costa Silva ; Salgado, Joana Rosmaninho ; Kaster, Manuella; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 39 | 11-May-2011 | Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons | Sousa-Ferreira, Lígia ; Álvaro, Ana Rita ; Aveleira, Célia ; Santana, Magda ; Brandão, Inês ; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 40 | 9-Aug-2023 | A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia | Martins, Mariana ; Oliveira, Ana Rafaela ; Martins, Solange ; Vieira, José Pedro; Perdigão, Pedro ; Fernandes, Ana Rita; Almeida, Luís Pereira de ; Palma, Paulo Jorge ; Sequeira, Diana Bela ; Santos, João Miguel Marques ; Duque, Frederico ; Oliveira, Guiomar ; Cardoso, Ana Luísa ; Peça, João ; Seabra, Catarina Morais | article | openAccess |
| 41 | 1-Jun-2023 | The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits | Koppenol, Rebekah; Conceição, André ; Afonso, Inês T.; Afonso-Reis, Ricardo; Costa, Rafael G.; Tomé, Sandra ; Teixeira, Diogo ; da Silva, Joana Pinto; Codêsso, José Miguel ; Brito, David V. C.; Mendonça, Liliana ; Marcelo, Adriana ; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio | article | openAccess |
| 42 | 10-May-2023 | In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration | Pereira, Patrícia ; Neto, Ana S.; Rodrigues, Ana Sofia ; Barros, Inês ; Miranda, Catarina O. ; Santos, João Ramalho ; Almeida, Luís Pereira de ; Ferreira, José M. F.; Coelho, Jorge ; Fonseca, Ana C. | article | openAccess |
| 43 | Apr-2023 | A standardised protocol for blood and cerebrospinal fluid collection and processing for biomarker research in ataxia | Santana, Magda M. ; Gaspar, Laetitia S. ; Pinto, Maria M. ; Silva, Patrick Joel da ; Adão, Diana ; Pereira, Dina ; Ribeiro, Joana Afonso; Cunha, Inês ; Huebener-Schmid, Jeannette; Raposo, Mafalda; Ferreira, Ana F.; Faber, Jennifer; Kuhs, Sandra; Garcia-Moreno, Hector; Reetz, Kathrin; Thieme, Andreas; Infante, Jon; van de Warrenburg, Bart P. C.; Giunti, Paola; Riess, Olaf; Schöls, Ludger; Lima, Manuela ; Klockgether, Thomas; Januário, Cristina ; Almeida, Luís Pereira de | article | openAccess |
| 44 | 2-Feb-2023 | Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation | Soares, Maria ; Pinto, Maria M. ; Nobre, Rui J. ; Almeida, Luís Pereira de ; Rasteiro, Maria da Graça ; Santos, Teresa Almeida ; Santos, João Ramalho ; Sousa, Ana Paula | article | openAccess |
| 45 | Dec-2023 | Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome | Ferreira-Marques, Marisa ; Carvalho, André; Franco, Ana Catarina ; Leal, Ana; Botelho, Mariana ; Carmo-Silva, Sara ; Águas, Rodolfo ; Cortes, Luísa ; Lucas, Vasco; Real, Ana Carolina; López-Otín, Carlos; Nissan, Xavier; Almeida, Luís Pereira de ; Cavadas, Cláudia ; Aveleira, Célia A. | article | openAccess |
| 46 | Feb-2023 | The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors | Hengel, Holger; Martus, Peter; Faber, Jennifer; Giunit, Paola; Garcia-Moreno, Hector; Solanky, Nita; Klockgether, Thomas; Reetz, Kathrin; van de Warrenburg, Bart P.; Santana, Magda M. ; Silva, Patrick Joel da ; Cunha, Inês ; Almeida, Luís Pereira de ; Timmann, Dagmar; Infante, Jon; de Vries, Jeroen; Lima, Manuela ; Pires, Paula; Bushara, Khalaf; Jacobi, Heike; Onyike, Chiadi; Schmahmann, Jeremy D.; Hübener-Schmid, Jeannette; Synofzik, Matthis; Schöls, Ludger | article | openAccess |
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