Laranjinha, João
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Laranjinha, João
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Laranjinha, João
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Laranjinha, João
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UC Researcher
Biography
João Laranjinha is professor of Biochemistry and Molecular Biology at the Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. He graduated in Pharmaceutical Sciences (University of Coimbra) in 1984 and got a PhD in Biochemistry (University of Coimbra) in 1996. He did Postdoc studies with Enrique Cadenas in 1997-1998 at the Dept. Molecular Pharmacology and Toxicology, University Southern California, Los Angeles, USA. His research is focused on the functional impact of nitric oxide in the brain as a neurometabolic regulator and as a mediator of neurovascular coupling with impact in aging and neurodegeneration. He is also interested in dietary nitrite-driven regulatory processes, encompassing the non-enzymatic production of nitric oxide along the nitrate:nitrite:NO pathway. He has been awarded several prizes, including the Science and Humanity award by The Oxygen Club of California and is member of the editorial board of major journals in his area of research, including Redox Biology, Free Radical Biology and Medicine, Archives of Biochemistry and Biophysics, Free Radical Research and Biofactors. He has chaired the organizing and scientific committees of several international conferences, including the European (SFRRE 2007) and International (SFRRI 2018) meetings of the Society for Free Radical Research. He has been member of the council of the European Society for Neurochemistry and the European Society for Free Radical Research for several years and President of the Portuguese Biochemical Society (2014-18). Currently, he serves as member of the Advanced Courses Committee of FEBS and as the president of the General Assembly of the Portuguese Biochemical Society.
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Results 1-27 of 27 (Search time: 0.022 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2008 | 3,4-Dihydroxyphenylacetic acid (DOPAC) modulates the toxicity induced by nitric oxide in PC-12 cells via mitochondrial dysfunctioning | Nunes, Carla ; Almeida, Leonor ; Laranjinha, João | article | openAccess |
| 2 | 2018 | Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus | Lourenço, Cátia F. ; Ledo, Ana ; Caetano, Miguel ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |
| 3 | 2003 | Antioxidant protection of low density lipoprotein by procyanidins: structure/activity relationships | Porto, Patrícia Andréia Leite da Silva ; Laranjinha, João António Nave ; Freitas, Victor Armando Pereira de | article | openAccess |
| 4 | 15-Jun-2013 | Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brain | Santos, Ricardo M. ; Rodrigues, Marcelo S. ; Laranjinha, João ; Barbosa, Rui M. | article | openAccess |
| 5 | Nov-2005 | Concentration Dynamics of Nitric Oxide in Rat Hippocampal Slices | Ledo, Ana ; Barbosa, Rui M. ; Cadenas, Enrique ; Gerhardt, Greg ; Laranjinha, João | article | openAccess |
| 6 | 29-Nov-2005 | Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor | Ledo, Ana ; Barbosa, Rui M. ; Gerhardt, Greg A. ; Cadenas, Enrique ; Laranjinha, João | article | openAccess |
| 7 | 26-Sep-2008 | Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro | Bem, Andreza Fabro de ; Farina, Marcelo ; Portella, Rafael de Lima ; Nogueira, Cristina Wayne ; Dinis, Teresa C. P. ; Laranjinha, João A. N. ; Almeida, Leonor M. ; Rocha, João Batista Teixeira | article | openAccess |
| 8 | 2005 | Electrochemical measurement of endogenously produced nitric oxide in brain slices using Nafion/o-phenylenediamine modified carbon fiber microelectrodes | Ferreira, Nuno R. ; Ledo, Ana ; Frade, João G. ; Gerhardt, Greg A. ; Laranjinha, João ; Barbosa, Rui M. | article | openAccess |
| 9 | 2-Mar-2023 | Epigenetic Modifications Induced by the Gut Microbiota May Result from What We Eat: Should We Talk about Precision Diet in Health and Disease? | Reva, Katerina; Laranjinha, João ; Rocha, Bárbara S. | article | openAccess |
| 10 | Oct-2017 | European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) | Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G.; Lopez, Manuela G.; Olaso-Gonzalez, Gloria; Petry, Andreas; Schulz, Rainer; Vina, Jose; Winyard, Paul; Abbas, Kahina; Ademowo, Opeyemi S.; Afonso, Catarina B.; Andreadou, Ioanna; Antelmann, Haike; Antunes, Fernando; Aslan, Mutay; Bachschmid, Markus M.; Barbosa, Rui M. ; Belousov, Vsevolod; Berndt, Carsten; Bernlohr, David; Bertrán, Esther; Bindoli, Alberto; Bottari, Serge P.; Brito, Paula M. ; Carrara, Guia; Casas, Ana I.; Chatzi, Afroditi; Chondrogianni, Niki; Conrad, Marcus; Cooke, Marcus S.; Costa, João G.; Cuadrado, Antonio; My-Chan Dang, Pham; De Smet, Barbara; Debelec-Butuner, Bilge; Dias, Irundika H K; Dunn, Joe Dan; Edson, Amanda J; El Assar, Mariam; El-Benna, Jamel; Ferdinandy, Péter; Fernandes, Ana S.; Fladmark, Kari E.; Förstermann, Ulrich; Giniatullin, Rashid; Giricz, Zoltán; Görbe, Anikó; Griffiths, Helen; Hampl, Vaclav; Hanf, Alina; Herget, Jan; Hernansanz-Agustín, Pablo; Hillion, Melanie; Huang, Jingjing; Ilikay, Serap; Jansen-Dürr, Pidder; Jaquet, Vincent; Joles, Jaap A; Kalyanaraman, Balaraman; Kaminskyy, Danylo; Karbaschi, Mahsa; Kleanthous, Marina; Klotz, Lars-Oliver; Korac, Bato; Korkmaz, Kemal Sami; Koziel, Rafal; Kračun, Damir; Krause, Karl-Heinz; Kren, Vladimir ; Krieg, Thomas; Laranjinha, João ; Lazou, Antigone; Li, Huige; Martínez-Ruiz, Antonio; Matsui, Reiko; McBean, Gethin J.; Meredith, Stuart P.; Messens, Joris; Miguel, Verónica; Mikhed, Yuliya; Milisav, Irina; Milković, Lidija; Miranda-Vizuete, Antonio; Mojović, Miloš; Monsalve, María; Mouthuy, Pierre-Alexis; Mulvey, John; Münzel, Thomas; Muzykantov, Vladimir; Nguyen, Isabel T. N.; Oelze, Matthias; Oliveira, Nuno G; Palmeira, Carlos M. ; Papaevgeniou, Nikoletta; Pavićević, Aleksandra; Pedre, Brandán; Peyrot, Fabienne; Phylactides, Marios; Pircalabioru, Gratiela G.; Pitt, Andrew R.; Poulsen, Henrik E.; Prieto, Ignacio; Rigobello, Maria Pia; Robledinos-Antón, Natalia; Rodríguez-Mañas, Leocadio; Rolo, Anabela P. ; Rousset, Francis; Ruskovska, Tatjana; Saraiva, Nuno ; Sasson, Shlomo; Schröder, Katrin; Semen, Khrystyna; Seredenina, Tamara; Shakirzyanova, Anastasia; Smith, Geoffrey L.; Soldati, Thierry; Sousa, Bebiana C.; Spickett, Corinne M.; Stancic, Ana; Stasia, Marie José; Steinbrenner, Holger; Stepanić, Višnja; Steven, Sebastian; Tokatlidis, Kostas; Tuncay, Erkan; Turan, Belma; Ursini, Fulvio; Vacek, Jan; Vajnerova, Olga; Valentová, Kateřina; Van Breusegem, Frank; Varisli, Lokman; Veal, Elizabeth A.; Yalçın, A Suha; Yelisyeyeva, Olha; Žarković, Neven; Zatloukalová, Martina; Zielonka, Jacek; Touyz, Rhian M.; Papapetropoulos, Andreas; Grune, Tilman; Lamas, Santiago; Schmidt, Harald H H W; Di Lisa, Fabio; Daiber, Andreas | article | openAccess |
| 11 | Aug-2021 | A High Fat/Cholesterol Diet Recapitulates Some Alzheimer's Disease-Like Features in Mice: Focus on Hippocampal Mitochondrial Dysfunction | Mancini, Gianni; Dias, Cândida ; Lourenço, Cátia F. ; Laranjinha, João ; Bem, Andreza de; Ledo, Ana | article | openAccess |
| 12 | Dec-2013 | Human colon adenocarcinoma HT-29 cell: electrochemistry and nicotine stimulation | Oliveira, S. C. B. ; Santarino, I. B. ; Enache, T. A. ; Nunes, C. ; Laranjinha, J. ; Barbosa, R. M. ; Brett, A. M. Oliveira | article | openAccess |
| 13 | 2022 | In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling activity | Ledo, A. ; Fernandes, E. ; Salvador, A. ; Laranjinha, J. ; Barbosa, R. M. | article | openAccess |
| 14 | 2000 | Inhibition of human LDL lipid peroxidation by phenol-rich beverages and their impact on plasma total antioxidant capacity in humans | Serafini, Mauro ; Laranjinha, João A. N. ; Almeida, Leonor M. ; Maiani, G. | article | openAccess |
| 15 | 28-May-2008 | LDL Isolated from Plasma-Loaded Red Wine Procyanidins Resist Lipid Oxidation and Tocopherol Depletion | Lourenço, Cátia F. ; Gago, Bruno ; Barbosa, Rui M. ; Freitas, Víctor de ; Laranjinha, João | article | openAccess |
| 16 | 28-Jul-2017 | Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays | Lourenço, Cátia F. ; Ledo, Ana ; Gerhardt, Greg A. ; Laranjinha, João ; Barbosa, Rui M. | article | openAccess |
| 17 | 2015 | Neurovascular and neurometabolic derailment in aging and Alzheimer's disease | Lourenço, Cátia F. ; Ledo, Ana ; Dias, Cândida ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |
| 18 | 2004 | Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions | Ledo, Ana ; Frade, João ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |
| 19 | 2012 | Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration | Santos, Ricardo M. ; Lourenço, Cátia F. ; Ledo, Ana ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |
| 20 | 2021 | Nitric Oxide Pathways in Neurovascular Coupling Under Normal and Stress Conditions in the Brain: Strategies to Rescue Aberrant Coupling and Improve Cerebral Blood Flow | Lourenço, Cátia F. ; Laranjinha, João | article | openAccess |
| 21 | 2002 | Oxidation of DOPAC by nitric oxide: effect of superoxide dismutase | Laranjinha, João ; Cadenas, Enrique | article | openAccess |
| 22 | 2008 | The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions | Gago, Bruno ; Nyström, Thomas ; Cavaleiro, Carlos ; Rocha, Bárbara S. ; Barbosa, Rui M. ; Laranjinha, João ; Lundberg, Jon O. | article | openAccess |
| 23 | 2007 | Red wine-dependent reduction of nitrite to nitric oxide in the stomach | Gago, Bruno ; Lundberg, Jon O. ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |
| 24 | 2005 | Redox interactions of nitric oxide with dopamine and its derivatives | Antunes, Fernando ; Nunes, Carla ; Laranjinha, João ; Cadenas, Enrique | article | openAccess |
| 25 | Aug-2016 | Role of nitrite, urate and pepsin in the gastroprotective effects of saliva | Rocha, Bárbara S. ; Lundberg, Jon O. ; Radi, Rafael; Laranjinha, João | article | openAccess |
| 26 | Feb-2013 | Self-mixing microprobe for monitoring microvascular perfusion in rat brain | Figueiras, Edite ; Oliveira, Ricardo ; Lourenço, Cátia F. ; Campos, Rita ; Humeau-Heurtier, Anne ; Barbosa, Rui M. ; Laranjinha, João ; Requicha Ferreira, Luís F. ; de Mul, Frits F M | article | openAccess |
| 27 | 9-May-2013 | The redox interplay between nitrite and nitric oxide: From the gut to the brain | Pereira, Cassilda ; Ferreira, Nuno R. ; Rocha, Bárbara S. ; Barbosa, Rui M. ; Laranjinha, João | article | openAccess |