Rego, A. Cristina
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Rego, A. Cristina
Name
Rego, Ana Cristina
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Rego, Ana Cristina
Rego, A. C.
Rego, A. C.
Unidade de I&D
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UC Researcher
Biography
Ana Cristina Rego (Ph.D.) is Associate Professor at the Faculty of Medicine, University of Coimbra (FMUC), lecturing classes of Biochemistry, Neuroscience and Neurobiology, and is head of the research group ‘Mitochondria and Neurodegenerative Disorders’ (current designation) at the Center for Neuroscience and Cell Biology (CNC), Univ. Coimbra (UC), since 2003. AC Rego initiated as Teaching Assistant in 1997 at FMUC, was Assistant Professor since 1999, and received the Tenure positition in 2004 and the 'Agregação' degree in 2010. AC Rego obtained the Master degree in Cell Biology in 1994 and the Ph.D. in Cell Biology in 1999 at UC, under the supervision of Prof. Catarina R. Oliveira, and was postdoctoral researcher in the Lab of Prof. David G. Nicholls, at the Univ. Dundee, Scotland, UK, and visiting researcher at the Buck Institute, Novato, CA, USA (David Nicholls Lab), from 1998-2000. In 2004-05 AC Rego was the coordinator of the BEB PhD Programme at CNC. The research group coordinated by AC Rego at CNC-UC investigates molecular mechanisms of familial and age-related neurodegenerative disorders, including Huntington’s and Alzheimer’s diseases, focusing on changes in mitochondrial function, dynamics and biogenesis and metabolic deregulation, glutamatergic postsynaptic dysfunction, and related exosomal content. Funding has been garnered by HighQ Foundation (USA), Lundbeck Foundation, ‘Instituto de Investigação Interdisciplinar’ (IIIUC), ‘Fundação para a Ciência e a Tecnologia’ (FCT) and EHDN-European Huntington Disease Network projects, two 1st edition major‘prizes/awards promoted by Santa Casa da Misericórdia de Lisboa’ (SCML) and ‘Fundação Luso Americana para o Desenvolvimento’ (FLAD) , as well as through industry contracts (e.g. TEVA, Sigma-Tau, Mycology Lab). AC Rego holds a H-factor of 44 (i10=98, at Google Scholar) and ~6400 citations, published 117 peer-reviewed articles (92 original publications), 23 book chapters (11 in portuguese) and more than 110 abstracts in research meetings. AC Rego also supervised/co-supervised the work of several post-doctoral fellows and a 'Ciência-FCT' researcher, 18 Ph.D. students and 37 Master students (concluded degrees). AC Rego acts as a reviewer for scientific journals and funding bodies, including Parkinson's UK, Alzheimer’s Research UK, Austrian Science Fund (FWF), Agence Nationale de la Recherche (ANR), Auckland Medical Research Foundation (AMRF), Telethon Fondazione, Israel Science Foundation, Wellcome Trust and Alzheimer’s Association. ACR is member of the ERA-Chair recruitment and monitoring team ERAatUC, at University of Coimbra, member of the board of CNC-UC, Vice-President of the Portuguese Brain Council and President of the Portuguese Society for Neuroscience (SPN).
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Results 1-27 of 27 (Search time: 0.025 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | Feb-2015 | Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts | Naia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina | article | openAccess |
| 2 | 2007 | Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine | Cunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 3 | 2009 | BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons | Almeida, S. ; Laço, M. ; Cunha-Oliveira, T. ; Oliveira, C. R. ; Rego, A. C. | article | openAccess |
| 4 | Sep-2011 | Bioenergetic dysfunction in Huntington's disease human cybrids | Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Nascimento, Maria V. ; Ribeiro, Márcio ; Proença, M. Teresa ; Januário, Cristina ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 5 | 2008 | Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs | Cunha-Oliveira, Teresa ; Rego, Ana Cristina ; Oliveira, Catarina R. | article | openAccess |
| 6 | Feb-2012 | Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathways | Cunha-Oliveira, Teresa ; Ferreira, Ildete L. ; Rego, A. Cristina | bookPart | openAccess |
| 7 | 2005 | Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide | Cunha-Oliveira, T. ; Rego, A. C. ; Morgadinho, M. T. ; Sarmento, A. ; Macedo, T. ; Oliveira, C. R. | conferenceObject | openAccess |
| 8 | 2006 | Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, Maria Teresa ; Macedo, Tice ; Oliveira, Catarina Resende | article | openAccess |
| 9 | Sep-2012 | Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice | Pereira, Frederico ; Cunha-Oliveira, Teresa ; Viana, Sofia ; Travassos, Ana Sofia ; Nunes, Sara ; Silva, Carlos ; Prediger, Rui ; Rego, Ana Cristina ; Ali, Syed ; Fontes Ribeiro, Carlos Alberto | article | closedAccess |
| 10 | 2009 | Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF | Almeida, Sandra ; Cunha-Oliveira, Teresa ; Laço, Mário ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 11 | 9-Mar-2012 | Efeito crónico da heroína e do peróxido de hidrogénio em células PC12 | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, M. Teresa ; Macedo, Tice R. ; Oliveira, Catarina R. | article | openAccess |
| 12 | 8-Mar-2012 | Expression of NR1/NR2B N-Methyl-d-Aspartate Receptors Enhances Heroin Toxicity in HEK293 Cells | Domingues, António ; Cunha-Oliveira, Teresa ; Laço, Mário L. N. ; Macedo, Tice ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 13 | 15-Nov-2012 | Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells | Ribeiro, Márcio ; Rosenstock, Tatiana ; Cunha-Oliveira, Teresa ; Ferreira, Ildete ; Oliveira, Catarina R. ; Rego, Ana Cristina | article | openAccess |
| 14 | 2005 | Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis | Cunha-Oliveira, T. ; Rego, A. C. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 15 | 8-Mar-2017 | Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease | Naia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina | article | openAccess |
| 16 | 2013 | Medical Toxicology of Drugs of Abuse | Cunha-Oliveira, Teresa ; Rego, Ana Cristina ; Carvalho, Félix ; Oliveira, Catarina R. | bookPart | openAccess |
| 17 | 2006 | Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine | Cunha-Oliveira, T. ; Rego, A. C. ; Cardoso, S. M. ; Borges, F. ; Swerdlow, R. ; Macedo, T. ; Oliveira, C. R. | article | openAccess |
| 18 | 2011 | Molecular interaction between cocaine and opioids. Implications on Speedball's toxicity | Cunha-Oliveira, T. ; Silva, L. ; Silva, A. M. ; Santos, M. S. ; Garrido, J. ; Borges, F. ; Rego, A. C. ; Oliveira, C. R. | conferenceObject | openAccess |
| 19 | 2021 | MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile | Jacinto, Sandra; Guerreiro, Patrícia; Oliveira, Rita Machado de; Oliveira, Teresa Cunha ; Santos, Maria João ; Grazina, Manuela ; Rego, A. Cristina ; Outeiro, Tiago F. | article | openAccess |
| 20 | 7-Nov-2007 | Neuronal dysfunction induced by drugs of abuse | Oliveira, Maria Teresa Martins da Cunha | doctoralThesis | openAccess |
| 21 | 2012 | Neurotoxicity of cocaine | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. | bookPart | openAccess |
| 22 | 8-Mar-2012 | Neurotoxicity of heroin-cocaine combinations in rat cortical neurons | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina R. | article | openAccess |
| 23 | 28-Aug-2014 | Oxidative Stress and Drugs of Abuse: An Update | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. | article | openAccess |
| 24 | Sep-2013 | Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 25 | 1-Nov-2012 | Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 26 | 2007 | Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina Resende | article | openAccess |
| 27 | Oct-2006 | Synthesis and Cytotoxic Profile of 3,4-Methylenedioxymethamphetamine (“Ecstasy”) and Its Metabolites on Undifferentiated PC12 Cells: A Putative Structure−Toxicity Relationship | Milhazes, Nuno ; Cunha-Oliveira, Teresa ; Martins, Pedro ; Garrido, Jorge ; Oliveira, Catarina ; Rego, A. Cristina ; Borges, Fernanda | article | openAccess |