Browsing by Subject Drug Design
Results 1 to 18 of 18
Issue Date | Title | Author(s) | Type | Access |
---|---|---|---|---|
Dec-2023 | Artificial intelligence for prediction of biological activities and generation of molecular hits using stereochemical information | Pereira, Tiago O. ; Abbasi, Maryam ; Oliveira, Rita I. ; Guedes, Romina A. ; Salvador, Jorge A. R. ; Arrais, Joel P. | article | openAccess |
2016 | Can the CEIBA Cocktail Designed for Human Cytochrome P450 Enzymes be Used in the Rat for Drug Interaction Studies? | Magalhães, Paulo ; De Andrés, Fernando; Falcão, Amílcar ; LLerena, Adrián; Alves, Gilberto | article | openAccess |
25-Oct-2019 | Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design | Guedes, Romina A. ; Aniceto, Natália; Andrade, Marina A. P.; Salvador, Jorge A. R. ; Guedes, Rita C. | article | openAccess |
27-Mar-2019 | A Complete Assessment of Dopamine Receptor- Ligand Interactions through Computational Methods | Bueschbell, Beatriz ; Barreto, Carlos A. V. ; Preto, Antonio J. ; Schiedel, Anke C.; Moreira, Irina S. | article | openAccess |
16-Jul-2016 | Computational Approaches for the Discovery of Human Proteasome Inhibitors: An Overview | Guedes, Romina A. ; Serra, Patrícia; Salvador, Jorge A. R. ; Guedes, Rita C. | article | openAccess |
4-Apr-2023 | Deep-Learning Application to in silico Drug Design | Gomes, António José Preto Martins | doctoralThesis | openAccess |
9-Mar-2021 | Diversity oriented Deep Reinforcement Learning for targeted molecule generation | Pereira, Tiago ; Abbasi, Maryam ; Ribeiro, Bernardete ; Arrais, Joel P. | article | openAccess |
30-Sep-2022 | Docking based strategies for the validation of deep learning generative models - And the search for novel ligands for A2aR, JAK2, KOR AND USP7. | Avila, Henrique de Vasconcellos | masterThesis | openAccess |
16-Sep-2021 | Drug Discovery with Generative Adversarial Networks | Santos, Beatriz de Jesus Pereira | masterThesis | embargoedAccess |
28-Sep-2022 | End-to-End Transformer-based Approach for Optimized De Novo Drug Design | Machado, Ana Catarina Dias | masterThesis | embargoedAccess |
Jan-2009 | Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety? | Pereira, Cláudia V. ; Moreira, Ana C. ; Pereira, Susana P. ; Machado, Nuno G. ; Carvalho, Filipa S. ; Sardão, Vilma A. ; Oliveira, Paulo J. | article | openAccess |
22-Jul-2020 | Multi-Objective Deep Reinforcement Learning in Drug Discovery | Pereira, Tiago Oliveira | masterThesis | embargoedAccess |
7-Feb-2019 | New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease | Rajeshwari, Rajeshwari; Chand, Karam; Candeias, Emanuel ; Cardoso, Sandra M. ; Chaves, Sílvia; Santos, M. Amélia | article | openAccess |
2017 | Properties of halogenated and sulfonated porphyrins relevant for the selection of photosensitizers in anticancer and antimicrobial therapies | Pucelik, Barbara; Paczyński, Robert; Dubin, Grzegorz; Pereira, Mariette M. ; Arnaut, Luís G. ; Dąbrowski, Janusz M. | article | openAccess |
11-Apr-2021 | Recent Developments in New Therapeutic Agents against Alzheimer and Parkinson Diseases: In-Silico Approaches | Cruz-Vicente, Pedro; Passarinha, Luís A.; Silvestre, Samuel Martins ; Gallardo, Eugenia | article | openAccess |
8-Aug-2021 | Response of Osteosarcoma Cell Metabolism to Platinum and Palladium Chelates as Potential New Drugs | Martins, Ana S. ; Batista de Carvalho, Ana L. M. ; Marques, Maria Paula M. ; Gil, Ana M | article | openAccess |
5-Jul-2021 | Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium | Alves, Nuno Guerreiro ; Bártolo, Inês; Alves, Américo J. S. ; Fontinha, Diana; Francisco, Denise; Lopes, Susana M. M.; Soares, Maria I. L. ; Simões, Carlos J. V. ; Prudêncio, Miguel ; Taveira, Nuno; Pinho e Melo, Teresa M. V. D. | article | embargoedAccess |
2-Mar-2021 | Synthesis of Computationally Designed 2,5(6)-Benzimidazole Derivatives via Pd-Catalyzed Reactions for Potential E. coli DNA Gyrase B Inhibition | Aroso, Rafael T. ; Guedes, Rita C. ; Pereira, Mariette M. | article | openAccess |