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Issue DateTitleAuthor(s)TypeAccess
110-Oct-2013Spatial memory impairments in a prediabetic rat modelSoares, E. ; Prediger, R. D. ; Nunes, S. ; Castro, A. A. ; Viana, S .D. ; Lemos, C. ; Souza, C. M. De ; Agostinho, P. ; Cunha, R. A. ; Carvalho, E. ; Ribeiro, C. A. Fontes ; Reis, F. ; Pereira, F. C. articleopenAccess
21-Sep-2014Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatmentLopes, P. C. ; Fuhrmann, A. ; Carvalho, F. ; Sereno, J. ; Santos, M. R. ; Pereira, M. J. ; Eriksson, J. W. ; Reis, F. ; Carvalho, E. articleopenAccess
32018Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of DiabetesTeodoro, João S. ; Nunes, Sara ; Rolo, Anabela P. ; Reis, Flávio ; Palmeira, Carlos M. articleopenAccess
423-Nov-2021Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial BioenergeticsNunes, Sara ; Viana, Sofia D. ; Preguiça, Inês ; Alves, André ; Fernandes, Rosa ; Teodoro, João S. ; Matos, Patrícia ; Figueirinha, Artur ; Salgueiro, Lígia ; André, Alexandra; Silva, Sara; Jarak, Ivana ; Carvalho, Rui A. ; Cavadas, Cláudia ; Rolo, Anabela P. ; Palmeira, Carlos M. ; Pintado, Maria M.; Reis, Flávio articleopenAccess
514-Nov-2020Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar RatsNunes, Sara ; Viana, Sofia D. ; Preguiça, Inês ; Alves, André ; Fernandes, Rosa ; Teodoro, João S. ; Figueirinha, Artur ; Salgueiro, Lígia ; Silva, Sara; Jarak, Ivana ; Carvalho, Rui A. ; Cavadas, Cláudia ; Rolo, Anabela P. ; Palmeira, Carlos M. ; Pintado, Maria M.; Reis, Flávio articleopenAccess
613-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa ; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Pinho e Melo, Teresa M. V. D. ; Saraiva, LucíliaarticleembargoedAccess
75-Nov-2019Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic DiseasesGomes, Pedro ; Leal, Helena; Mendes, Alexandrina F. ; Reis, Flávio ; Cavadas, Cláudia articleembargoedAccess
86-Sep-2021Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional studyAzul, Anabela Marisa ; Almendra, Ricardo ; Quatorze, Marta; Loureiro, Adriana ; Reis, Flávio ; Tavares, Rui ; Mota-Pinto, Anabela ; Cunha, António ; Rama, Luís ; Malva, João Oliveira ; Santana, Paula ; Santos, João Ramalho ; HeaLIQs4Cities, consortiumarticleopenAccess
913-Apr-2021A selective p53 activator and anticancer agent to improve colorectal cancer therapyRamos, Helena; Soares, Maria I. L. ; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia ; Reis, Flávio ; Monteiro, Filipe A.; Nunes, Cláudia; Reis, Salette ; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa; Carvalho, A. T. P. ; Veselska, Renata; Inga, Alberto; Melo, Teresa M. V. D. Pinho e ; Saraiva, LucíliaarticleopenAccess
102017Therapeutic strategies targeting oxidative stress to improve dyslipidemia and left ventricular hypertrophyReis, Flávio articleopenAccess
112017Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 DiabetesMega, Cristina; Teixeira-de-Lemos, Edite; Fernandes, Rosa ; Reis, Flávio articleopenAccess
12Jun-2017DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer propertiesSoares, Joana; Espadinha, Margarida; Raimundo, Liliana; Ramos, Helena; Gomes, Ana Sara; Gomes, Sara; Loureiro, Joana B.; Inga, Alberto; Reis, Flávio ; Gomes, Célia ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess
1321-Jun-2017Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose DietBurgeiro, Ana ; Cerqueira, Manuela G. ; Varela-Rodríguez, Bárbara M; Nunes, Sara ; Neto, Paula; Pereira, Frederico C. ; Reis, Flávio ; Carvalho, Eugenia articleopenAccess
142017mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging [Editorial]Das, Anindita; Reis, Flávio ; Maejima, Yasuhiro; Cai, Zhiyou; Ren, JunarticleopenAccess
1521-Oct-2016Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cellsFerreira-Teixeira, Margarida ; Paiva-Oliveira, Daniela ; Parada, Belmiro ; Alves, Vera ; Sousa, Vítor ; Chijioke, Obinna; Münz, Christian; Reis, Flávio ; Rodrigues-Santos, Paulo ; Gomes, Célia articleopenAccess
162016Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approachesMadureira, Ana Raquel; Nunes, Sara ; Campos, Débora A; Fernandes, João C. ; Marques, Cláudia; Zuzarte, Mónica ; Gullón, Beatriz; Rodríguez-Alcalá, Luís M.; Calhau, Conceição ; Sarmento, Bruno ; Gomes, Ana Maria; Pintado, Maria Manuela ; Reis, Flávio articleopenAccess
1725-Dec-2015Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated AnemiaGarrido, Patrícia ; Ribeiro, Sandra; Fernandes, João ; Vala, Helena; Rocha-Pereira, Petronila ; Bronze-da-Rocha, Elsa; Belo, Luís; Costa, Elísio; Santos-Silva, Alice; Reis, Flávio articleopenAccess
182015The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?Godinho, Ricardo ; Mega, Cristina ; Teixeira-Lemos, Edite ; Carvalho, Eugenia ; Teixeira, Frederico ; Fernandes, Rosa ; Reis, Flávio articleopenAccess
192015Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat modelGarrido, Patrícia ; Ribeiro, Sandra; Fernandes, João C. ; Vala, Helena; Bronze-da-Rocha, Elsa; Rocha-Pereira, Petronila ; Belo, Luís; Costa, Elísio; Santos-Silva, Alice; Reis, Flávio articleopenAccess
202014Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkersSereno, José ; Nunes, Sara ; Rodrigues-Santos, Paulo ; Vala, Helena; Rocha-Pereira, Petronila ; Fernandes, João ; Santos-Silva, Alice; Teixeira, Frederico ; Reis, Flávio articleopenAccess
2120-Mar-2014Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective propertiesMega, Cristina ; Vala, Helena; Rodrigues-Santos, Paulo ; Oliveira, Jorge; Teixeira, Frederico ; Fernandes, Rosa ; Reis, F. ; Lemos, Edite Teixeira de articleopenAccess
2220-May-2014Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat modelSereno, José ; Rodrigues-Santos, Paulo ; Vala, Helena; Rocha-Pereira, Petronila ; Alves, Rui; Fernandes, João; Santos-Silva, Alice; Carvalho, Eugenia ; Teixeira, Frederico ; Reis, F. articleopenAccess
232014Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animalsMarques, Catarina ; Mega, Cristina ; Gonçalves, Andreia ; Rodrigues-Santos, Paulo ; Lemos, Edite Teixeira de ; Teixeira, Frederico ; Fontes-Ribeiro, Carlos A. ; Reis, F. ; Fernandes, Rosa articleopenAccess
247-Mar-2013Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best markerNunes, Sara ; Soares, Edna ; Fernandes, João ; Viana, Sofia D. ; Carvalho, Eugenia ; Pereira, Frederico C. ; Reis, Flávio articleopenAccess
252010Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat modelSereno, José ; Parada, Belmiro ; Reis, Flávio ; Cunha, Fernanda X; Teixeira-Lemos, Edite ; Garrido, Patrícia ; Pinto, Rui; Rocha-Pereira, Petronila; Neto, Paula; Ruivo, José da Silva ; Santos, Paulo Rodrigues dos ; Nunes, Sara ; Mota, Alfredo ; Figueiredo, Arnaldo ; Teixeira, Frederico articleopenAccess
26Jan-2012Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the ratTeixeira, M. ; Rodrigues-Santos, P. ; Garrido, P. ; Costa, E; Parada, B. ; Sereno, J. ; Alves, R. ; Belo, L; Teixeira, F. ; Santos-Silva, A. ; Reis, F. articleopenAccess
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