Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113276
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leston, Sara | - |
dc.contributor.author | Freitas, Andreia | - |
dc.contributor.author | Rosa, João | - |
dc.contributor.author | Vila Pouca, Ana Sofia | - |
dc.contributor.author | Barbosa, Jorge | - |
dc.contributor.author | Reis-Santos, Patrick | - |
dc.contributor.author | Fonseca, Vanessa F. | - |
dc.contributor.author | Pardal, Miguel | - |
dc.contributor.author | Ramos, Fernando | - |
dc.date.accessioned | 2024-02-12T14:19:05Z | - |
dc.date.available | 2024-02-12T14:19:05Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 2076-3417 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/113276 | - |
dc.description.abstract | Anthropogenic chemical contamination represents a key stressor of natural environments with pharmaceuticals comprising a particular group of emerging pollutants with the potential to induce biological responses in non-target organisms. Therefore, an analytical method based on ultra-high-performance liquid chromatography coupled to time-of-flight tandem mass spectrometry (UHPLC-TOF-MS) was developed for estuarine and seawaters, targeting 63 globally used pharmaceuticals (including amoxicillin, ciprofloxacin, sulfamethoxazole, trimethoprim and venlafaxine included in the SurfaceWaterWatch List) from 8 therapeutic groups: antibiotics, analgesic, NSAIDs, antidepressants, -blockers, lipid regulators, anticonvulsants and antihypertensive drugs. The method presents high selectivity and sensitivity, with the limits of detection ranging from 0.01 to 8.92 ng/L and the limits of quantification from 0.02 to 29.73 ng/L. Considering precision, the highest value was achieved for amoxicillin (20.9%) and the lower for ofloxacin (2.6%), while recoveries ranged from 80.6 to 112.6%. Overall, the quantification method was highly efficient for multi-residues quantification in such complex environmental samples. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | PTDC/MAR-EST/3048/2014 | pt |
dc.relation | info:eu-repo/grantAgreement/UIDB/04292/2020/PT | pt |
dc.relation | info:eu-repo/grantAgreement/UIDP/04292/2020 | pt |
dc.relation | LA/P/0069/2020 | pt |
dc.relation | UIDB/04004/2021 | pt |
dc.relation | CENTRO-01-0145-FEDER-000007 | pt |
dc.relation | DL57/2016/IT057-18-7255 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | environmental contamination | pt |
dc.subject | emerging contaminants | pt |
dc.subject | drugs | pt |
dc.subject | seawater | pt |
dc.subject | UHPLC-TOF-MS | pt |
dc.title | Pharmaceuticals in Coastal Waters: An UHPLC-TOF-MS Multi-Residue Approach | pt |
dc.type | article | - |
degois.publication.firstPage | 5975 | pt |
degois.publication.issue | 10 | pt |
degois.publication.title | Applied Sciences (Switzerland) | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/app13105975 | pt |
degois.publication.volume | 13 | pt |
dc.date.embargo | 2023-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.researchunit | CFE - Centre for Functional Ecology - Science for People & the Planet | - |
crisitem.author.researchunit | MARE - Marine and Environmental Sciences Centre | - |
crisitem.author.researchunit | CFE - Centre for Functional Ecology - Science for People & the Planet | - |
crisitem.author.orcid | 0000-0001-9843-9465 | - |
crisitem.author.orcid | 0000-0001-6048-7007 | - |
crisitem.author.orcid | 0000-0002-6043-819X | - |
crisitem.project.grantno | MARE-Marine and Environmental Sciences Centre | - |
crisitem.project.grantno | MARE-Marine and Environmental Sciences Centre | - |
crisitem.project.grantno | ARNET- Aquatic Research Infrastructure Network | - |
crisitem.project.grantno | Centre for Functional Ecology - Science for People & the Planet | - |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais I&D MARE - Artigos em Revistas Internacionais I&D CFE - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Pharmaceuticals-in-Coastal-Waters-An-UHPLCTOFMS-MultiResidue-ApproachApplied-Sciences-Switzerland.pdf | 1.25 MB | Adobe PDF | View/Open |
Page view(s)
56
checked on Jul 24, 2024
Download(s)
45
checked on Jul 24, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License