General Statistics

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Geo Map
Region #
NA - North America 78405
EU - Europe 63294
AS - Asia, other 28152
SA - South America 12406
AF - Africa 2339
OC - Oceania 1377
Unknown Continent - Not applicable 1
Unknown 3407
Total 189381
Country #
US - United States of America 78110
PT - Portugal 25846
PL - Poland 16038
CN - China 14217
BR - Brazil 12256
SG - Singapore 9598
DE - Germany 6177
IE - Ireland 4341
RU - Russian Federation 1928
SE - Sweden 1619
other - Other Country 19173
Total 189303
City #
Ashburn 25408
Warsaw 15937
New York 8887
Inglewood 5143
Coimbra 4456
Beijing 4184
Dublin 4094
Singapore 3392
Redmond 3348
Mountain View 2141
other 93566
Total 170556
Most viewed items #
ID: 19020 - Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies 5143
ID: 19068 - Role of mtDNA-related mitoepigenetic phenomena in cancer 1882
ID: 10544 - Intranasal drug delivery: how, why and what for? 1511
ID: 19017 - Synergistic impact of endurance training and intermittent hypobaric hypoxia on cardiac function and mitochondrial energetic and signaling 1460
ID: 19071 - Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells 1438
ID: 19098 - Role of Mitochondria on the Neurological Effects of Cocaine 1385
ID: 19000 - Toxic Effects of Opioid and Stimulant Drugs on Undifferentiated PC12 Cells 1319
ID: 19016 - Oxidative Stress and Drugs of Abuse: An Update 1209
ID: 18996 - Towards the Maturation and Characterization of Smooth Muscle Cells Derived from Human Embryonic Stem Cells 1202
ID: 19050 - Neuronal Activity Induces Synaptic Delivery of hnRNP A2/B1 by a BDNF-Dependent Mechanism in Cultured Hippocampal Neurons 1199
ID: 19051 - Presynaptic A2A adenosine receptors dampen CB1 cannabinoid receptor-mediated inhibition of corticostriatal glutamatergic transmission 1198
ID: 19060 - Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress 1161
ID: 19086 - Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions? 1113
ID: 19061 - Intranasal administration of carbamazepine to mice: a direct delivery pathway for brain targeting 1103
ID: 19087 - Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety? 1102
ID: 19019 - The nucleolar protein Viriato/Nol12 is required for the growth and differentiation progression activities of the Dpp pathway during Drosophila eye development 1082
ID: 19052 - Role of Endothelial Progenitor Cells and Inflammatory Cytokines in Healing of Diabetic Foot Ulcers 1071
ID: 19042 - Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages 1053
ID: 19055 - RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph Disease 1046
ID: 19073 - Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease 1029
ID: 19066 - Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts 1016
ID: 19058 - Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells 1012
ID: 19007 - Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice 1011
ID: 10595 - Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph disease 1006
ID: 19002 - Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF 994
ID: 19077 - Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse 994
ID: 14063 - Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guided assay using lipopolysaccharide-stimulated macrophages 992
ID: 19015 - Suicide gene therapy in cancer: Where do we stand now? 972
ID: 19008 - Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse 968
ID: 19099 - Membrane proteins structures: A review on computational modeling tools 915
ID: 19103 - Efeito crónico da heroína e do peróxido de hidrogénio em células PC12 896
ID: 19079 - Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types 872
ID: 19075 - Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity 867
ID: 19039 - Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice 842
ID: 19012 - Dissecting Regulatory Networks of Filopodia Formation in a Drosophila Growth Cone Model 827
ID: 18995 - Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD 826
ID: 19070 - Analysis of pro-apoptotic protein trafficking to and from mitochondria 815
ID: 19040 - Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: new set of data for predictive in silico ADME models 792
ID: 19095 - Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation 788
ID: 19096 - Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial function 785
ID: 19010 - Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin 780
ID: 19018 - Dysfunctional synapse in Alzheimer’s disease – a focus on NMDA receptors 777
ID: 19056 - New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death 777
ID: 18988 - Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis 772
ID: 19069 - Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts 771
ID: 18999 - Drugs of abuse induce apoptotic features in PC12 cells. 767
ID: 19064 - GSK3β and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation 766
ID: 18998 - Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathways 756
ID: 19013 - Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria 754
ID: 18993 - In Vitro Surfactant Structure-Toxicity Relationships: Implications for Surfactant Use in Sexually Transmitted Infection Prophylaxis and Contraception 751
ID: 19011 - Cdk5: Multitasking between physiological and pathological conditions 746
Total 55313


Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Tot
2019 00 0000 444106013531779 11141338 7088
2020 10831370 101612081239773 82861824746 1195676 10776
2021 1363899 8877997111020 909755652963 667698 10323
2022 1112810 2313747637475 89770712851039 19801892 13894
2023 6531080 19402690421 505145010863604 71486890 25046
2024 658211135 7165787783387075 5959000 00 54131
Ever 189381