Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/48362
Title: | Membrane proteins structures: A review on computational modeling tools | Authors: | Almeida, Jose G. Preto, Antonio J. Koukos, Panagiotis I. Bonvin, Alexandre M. J. J. Moreira, Irina S. |
Keywords: | Algorithms; Computational Biology; Humans; Membrane Proteins; Molecular Dynamics Simulation; Software | Issue Date: | 15-Jul-2017 | Project: | F/00578/2014 MEMBRANEPROT 659826 CENTRO-01-0145-FEDER-000008 TOP-PUNT grant BC.000664.1 |
Serial title, monograph or event: | Biochimica et Biophysica Acta (BBA) - Biomembranes | Volume: | 1859 | Issue: | 10 | Abstract: | Membrane proteins (MPs) play diverse and important functions in living organisms. They constitute 20% to 30% of the known bacterial, archaean and eukaryotic organisms' genomes. In humans, their importance is emphasized as they represent 50% of all known drug targets. Nevertheless, experimental determination of their three-dimensional (3D) structure has proven to be both time consuming and rather expensive, which has led to the development of computational algorithms to complement the available experimental methods and provide valuable insights. | URI: | https://hdl.handle.net/10316/48362 | DOI: | 10.1016/j.bbamem.2017.07.008 | Rights: | embargoedAccess |
Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais |
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BBA_Postprinting.pdf | 3.94 MB | Adobe PDF | View/Open |
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