Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/3852
Title: | To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate | Authors: | Empadinhas, Nuno Costa, Milton S. da |
Keywords: | Compatible solutes; Mannosylglycerate; Glucosylglycerate; Biosynthesis | Issue Date: | 2008 | Citation: | Systematic and Applied Microbiology. 31:3 (2008) 159-168 | Abstract: | Mannosylglycerate (MG) is an intracellular organic solute found in some red algae, and several thermophilic bacteria and hyperthermophilic archaea. Glucosylglycerate (GG) was identified at the reducing end of a polysaccharide from mycobacteria and in a free form in a very few mesophilic bacteria and halophilic archaea. MG has a genuine role in the osmoadaptation and possibly in thermal protection of many hyper/thermophilic bacteria and archaea, but its role in red algae, where it was identified long before hyperthermophiles were even known to exist, remains to be clarified. The GG-containing polysaccharide was initially detected in Mycobacterium phlei and found to regulate fatty acid synthesis. More recently, GG has been found to be a major compatible solute under salt stress and nitrogen starvation in a few microorganisms. This review summarizes the occurrence and physiology of MG accumulation, as well as the distribution of GG, as a free solute or associated with larger macromolecules. We also focus on the recently identified pathways for the synthesis of both molecules, which were elucidated by studying hyper/thermophilic MG-accumulating organisms. The blooming era of genomics has now allowed the detection of these genes in fungi and mosses, opening a research avenue that spans the three domains of life, into the role of these two sugar derivatives. | URI: | https://hdl.handle.net/10316/3852 | DOI: | 10.1016/j.syapm.2008.05.002 | Rights: | openAccess |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
file26e52dd7b416446191537863831e1e74.pdf | 304.28 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
22
checked on Oct 7, 2024
WEB OF SCIENCETM
Citations
22
checked on Oct 2, 2024
Page view(s) 50
491
checked on Oct 15, 2024
Download(s)
500
checked on Oct 15, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.