Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/113757
Title: An Overview on Antimicrobial Potential of Edible Terrestrial Plants and Marine Macroalgae Rhodophyta and Chlorophyta Extracts
Authors: Lomartire, Silvia 
Gonçalves, Ana M. M. 
Keywords: bioactive compounds; Rhodophyta; Chlorophyta; antimicrobial resistance; natural antibiotics; seaweeds
Issue Date: 28-Feb-2023
Publisher: MDPI
Project: This work is financed by national funds through FCT—Foundation for Science and Technology, I.P., within the scope of the projects LA/P/0069/2020 granted to the Associate Laboratory ARNET, UIDB/04292/2020—granted to MARE—Marine and Environmental Sciences Centre and UIDP/50017/2020+UIDB/50017/2020 (by FCT/MTCES) granted to CESAM—Centre for Environmental and Marine Studies. This research was co-financed by the project AlgaMar4antivirus—Marine MacroalgaE in the prevention and treatment of ANTIviral diseases (Coronavirus SARS-CoV-2) (FA_07_2018_009), funded by the Blue Fund under Public Notice No. 7 /2018—Scientific Research and Marine Technology. Silvia Lomartire thanks the Foundation for Science and Technology (FCT) for the financial support granted through the doctoral grant 2021.05005.BD. Ana M. M. Gonçalves acknowledges the University of Coimbra for the contract IT057-18-7253. 
Serial title, monograph or event: Marine Drugs
Volume: 21
Issue: 3
Abstract: Antibiotics are used to prevent and treat bacterial infections. After a prolonged use of antibiotics, it may happen that bacteria adapt to their presence, developing antibiotic resistance and bringing up health complications. Nowadays, antibiotic resistance is one of the biggest threats to global health and food security; therefore, scientists have been searching for new classes of antibiotic compounds which naturally express antimicrobial activity. In recent decades, research has been focused on the extraction of plant compounds to treat microbial infections. Plants are potential sources of biological compounds that express several biological functions beneficial for our organism, including antimicrobial activity. The high variety of compounds of natural origin makes it possible to have a great bioavailability of antibacterial molecules to prevent different infections. The antimicrobial activity of marine plants, also called seaweeds or macroalgae, for both Gram-positive and Gram-negative, and several other strains infective for humans, has been proven. The present review presents research focused on the extraction of antimicrobial compounds from red and green macroalgae (domain Eukarya, kingdom Plantae). Nevertheless, further research is needed to verify the action of macroalgae compounds against bacteria in vitro and in vivo, to be involved in the production of safe and novel antibiotics.
URI: https://hdl.handle.net/10316/113757
ISSN: 1660-3397
DOI: 10.3390/md21030163
Rights: openAccess
Appears in Collections:I&D MARE - Artigos em Revistas Internacionais
FCTUC Ciências da Vida - Artigos em Revistas Internacionais

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