Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/107110
Título: | The cerebellum is causally involved in episodic memory under aging | Autor: | Almeida, Armando Martins, Ana R. Amaral, Lénia Valério, Daniela Bukhari, Qasim Schu, Guilherme Nogueira, Joana Spínola, Mónica Soleimani, Ghazaleh Fernandes, Filipe Silva, Ana R. Fregni, Felipe Simis, Marcel Simões, Mário Peres, André |
Palavras-chave: | Cerebellum; Episodic memory decline; Neurostimulation | Data: | 7-Fev-2023 | Editora: | Springer Nature | Projeto: | info:eu-repo/grantAgreement/EC/H2020/802553/EU/Contentotopic mapping: the topographical organization of object knowledge in the brain info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH/BD/136029/2018/PT/The impact of Cognitive Reserve on healthy aging and dementia info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH/BD/137737/2018/PT/Local or Global The effects of transcranial direct current stimulation tDCS in brain processing. info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC/PSI-GER/30757/2017/PT/Seeing with your ears: how deafness-induced neuroplasticity impacts neural processing and auditory restoration efforts 2020.00524.CEECIND BIAL foundation grant #495/14 FAPESP-SPEC grant 17/12943-8 |
Título da revista, periódico, livro ou evento: | GeoScience | Resumo: | Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory performance under healthy aging that long outlast the stimulation period - healthy elderly individuals show episodic memory improvement both immediately after the intervention program and in a 4-month follow-up. These results demonstrate the causal relevance of the cerebellum in processes associated with long-term episodic memory, potentially highlighting its role in regulating and maintaining cognitive processing. Moreover, they point to the importance of non-pharmacological interventions that prevent or diminish cognitive decline in healthy aging. | URI: | https://hdl.handle.net/10316/107110 | ISSN: | 2509-2715 2509-2723 |
DOI: | 10.1007/s11357-023-00738-0 | Direitos: | openAccess |
Aparece nas coleções: | I&D CINEICC - Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
s11357-023-00738-0.pdf | 1.44 MB | Adobe PDF | Ver/Abrir |
Citações SCOPUSTM
2
Visto em 6/mai/2024
Citações WEB OF SCIENCETM
2
Visto em 2/mai/2024
Visualizações de página
115
Visto em 7/mai/2024
Downloads
54
Visto em 7/mai/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Este registo está protegido por Licença Creative Commons