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Issue DateTitleAuthor(s)TypeAccess
12019Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxiaNóbrega, Clévio David Rodrigues ; Mendonça, Liliana Simões ; Marcelo, Adriana Isabel do Vale ; Lamazière, Antonin; Tomé, Sandra Marisa Oliveira ; Despres, Gaetan; Matos, Carlos A; Mechmet, Fatich; Langui, Dominique; den Dunnen, Wilfred; Almeida, Luís Pereira de ; Cartier, Nathalie; Alves, Sandro José Paiva Fernandes articleembargoedAccess
2Mar-2018Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese miceMarques, Ana Patrícia; Cunha-Santos, Janete; Leal, Helena; Sousa-Ferreira, Lígia ; Pereira de Almeida, Luís ; Cavadas, Cláudia ; Rosmaninho-Salgado, Joana articleopenAccess
32012Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph diseaseSimões, Ana T. ; Gonçalves, Nélio ; Koeppen, Arnulf ; Déglon, Nicole ; Kügler, Sebastian ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleopenAccess
45-Mar-2014Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In VitroSousa-Ferreira, Lígia ; Aveleira, Célia ; Botelho, Mariana ; Álvaro, Ana Rita ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
52013Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph diseaseGonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de articleopenAccess
61-Jun-2011Effect of Food on the Pharmacokinetic Profile of Etamicastat (BIA 5-453)Vaz-da-Silva, Manuel ; Nunes, Teresa ; Rocha, José F. ; Falcão, Amílcar ; Almeida, Luis ; Soares-da-Silva, Patricio articleopenAccess
72014Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph diseaseSimões, Ana Teresa ; Gonçalves, Nélio ; Nobre, Rui Jorge ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleembargoedAccess
821-Aug-2014RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph DiseaseNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
92019Successes and Hurdles in Stem Cells Application and Production for Brain TransplantationHenrique, Daniel ; Moreira, Ricardo ; Schwamborn, Jens; Almeida, Luís Pereira de ; Mendonça, Liliana articleopenAccess
1014-May-2019Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and FunctionalityWalter, Jonas; Bolognin, Silvia; Antony, Paul M. A.; Nickels, Sarah L.; Poovathingal, Suresh K.; Salamanca, Luis; Magni, Stefano; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Almeida, Luís Pereira de ; Skupin, Alexander; Tronstad, Karl J.; Schwamborn, Jens C.articleopenAccess
112016Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activationFerreira-Marques, Marisa; Aveleira, Célia A. ; Carmo-Silva, Sara; Botelho, Mariana ; Pereira de Almeida, Luís ; Cavadas, Cláudia articleopenAccess
122017Generation of human iPSC line from a patient with laterality defects and associated congenital heart anomalies carrying a DAND5 missense alterationCristo, Fernando; Inácio, José M; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Almeida, Luís Pereira de ; Mendes, Patrícia; Martins, Duarte Saraiva; Maio, José; Anjos, Rui ; Belo, José A.articleopenAccess
131-Aug-2018Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cellsRodrigues, Carlos F. D. ; Serrano, Eurico ; Patrício, Maria I.; Val, Mariana; Albuquerque, Patrícia; Fonseca, João ; Gomes, Célia M. F. ; Abrunhosa, Antero ; Paiva, Artur ; Carvalho, Lina ; Botelho, Maria F. ; Almeida, Luís ; Carreira, Isabel M. ; Alpoim, Maria Carmen articleopenAccess
14May-2018Generation and characterization of a human iPS cell line from a patient-related control to study disease mechanisms associated with DAND5 p.R152H alterationPars, Selin; Cristo, Fernando; Inácio, José M.; Rosas, Graça; Carreira, Isabel Marques ; Melo, Joana Barbosa ; Mendes, Patrícia; Martins, Duarte Saraiva; Almeida, Luís Pereira de ; Maio, José; Anjos, Rui ; Belo, José A.articleopenAccess
155-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
16Mar-2016Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particlesConceição, Mariana ; Mendonça, Liliana ; Nóbrega, Clévio; Gomes, Célia ; Costa, Pedro ; Hirai, Hirokazu; Moreira, João Nuno ; Lima, Maria C. Pedroso de ; Manjunath, N.; Almeida, Luís Pereira de articleopenAccess
172016Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive ReviewAlves-Cruzeiro, João M. da Conceição ; Mendonça, Liliana ; Almeida, Luís Pereira de articleopenAccess
1811-May-2016Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathwayCunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
1922-Jun-2016Fibroblasts of Machado Joseph Disease patients reveal autophagy impairmentOnofre, Isabel ; Mendonça, Nuno ; Lopes, Sara ; Nobre, Rui J. ; Melo, Joana Barbosa ; Carreira, Isabel Marques ; Januário, Cristina ; Gonçalves, António Freire ; Almeida, Luís Pereira de articleopenAccess
202013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
212011Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult ratsSousa-Ferreira, Lígia ; Garrido, Manuel Joaquim Marques ; Nascimento-Ferreira, Isabel ; Nóbrega, Clévio ; Carvalho, Ana dos Santos ; Álvaro, Ana Rita Costa Silva ; Salgado, Joana Rosmaninho ; Kaster, Manuella; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
2211-May-2011Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neuronsSousa-Ferreira, Lígia ; Álvaro, Ana Rita ; Aveleira, Célia ; Santana, Magda ; Brandão, Inês ; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
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