Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/90775
Título: | Advanced Mechanochemistry Device for Sustainable Synthetic Processes | Autor: | Gomes, Carla Vinagreiro, Carolina dos Santos Damas, Liliana Reis Aquino, Gilberto Lucio Benedito Quaresma, Joana Filipa Pires d'Oliveira Chaves, Cristina Manuel Monteiro Pimenta, João Campos, José L. S. de A. Pereira, Maria Miguéns Piñeiro Gomez, Marta |
Data: | 19-Mai-2020 | Editora: | ACS Publications | Projeto: | UIDB/00313/2020 | Volume: | 5 | Número: | 19 | Resumo: | Mechanochemistry is an alternative for sustainable solvent-free processes that has taken the big step to become, in the near future, a useful synthetic method for academia and the fine chemical industry. The apparatus available, based on ball milling systems possessing several optimizable variables, requires too many control and optimization experiments to ensure reproducibility, which has limited its widespread utilization so far. Herein, we describe the development of an automatic mechanochemical single-screw device consisting of an electrical motor, a drill, and a drill chamber. The applicability and versatility of the new device are demonstrated by the implementation of di- and multicomponent chemical reactions with high reproducibility, using mechanical action exclusively. As examples, chalcones, dihydropyrimidinones, dihydropyrimidinethiones, pyrazoline, and porphyrins, were synthesized with high yields. The unprecedented sustainability is demonstrated by comparison of EcoScale and E-factor values of these processes with those previously described in the literature. | URI: | https://hdl.handle.net/10316/90775 | ISSN: | 2470-1343 | DOI: | 10.1021/acsomega.0c00521 | Direitos: | openAccess |
Aparece nas coleções: | I&D CQC - Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Gomes2020acsomega.pdf | 4.22 MB | Adobe PDF | Ver/Abrir |
Citações SCOPUSTM
13
Visto em 17/nov/2022
Citações WEB OF SCIENCETM
20
13
Visto em 2/mai/2023
Visualizações de página
259
Visto em 16/out/2024
Downloads
418
Visto em 16/out/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Este registo está protegido por Licença Creative Commons