Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/8505
Título: | Chorioretinal anastomosis and photodynamic therapy:a two-year follow-up study | Autor: | Silva, Rufino Cachulo, M. Figueira, João Abreu, José de Cunha-Vaz, J. |
Data: | 2007 | Citação: | Graefe's Archive for Clinical and Experimental Ophthalmology. 245:8 (2007) 1131-1139 | Resumo: | Abstract Background To evaluate the two-year efficacy of photodynamic therapy with Visudyne (PDT) in neovascular age-related macular degeneration (AMD) eyes with chorioretinal anastomosis (CRA). Methods A non-randomized, institutional, prospective study, of 28 consecutive eyes of 23 patients, with CRA, treated with PDT. Masked best corrected visual acuity (VA) and angiographic features at baseline and during the period of two years were evaluated. Results Twenty eight eyes completed one year and 19 eyes completed two years of follow-up. The number of treatments was 3 in the first year, and 0.8 in the second year. A VA loss < 3 lines occurred in 53% of the eyes, at two years. Treated eyes lost 0.5 lines in the first year and 2.4 lines in the second (p?<?0,01). Recurrence with additional significant VA loss occurred in four eyes (21%) during the second year. Fourteen eyes (74%) showed no fluorescein leakage at two years. Conclusion AMD eyes with chorioretinal anastomosis can benefit from PDT with Verteporfin at two years. However, during the second year significant additional VA loss occurs mainly due to recurrence. New modalities of treatment are necessary to achieve VA improvement in CRA eyes. | URI: | https://hdl.handle.net/10316/8505 | DOI: | 10.1007/s00417-006-0532-y | Direitos: | openAccess |
Aparece nas coleções: | FMUC Medicina - Artigos em Revistas Internacionais |
Mostrar registo em formato completo
Citações SCOPUSTM
28
Visto em 1/mai/2023
Citações WEB OF SCIENCETM
5
25
Visto em 2/abr/2024
Visualizações de página 50
618
Visto em 23/abr/2024
Downloads 50
343
Visto em 23/abr/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.