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|Title:||13C MRS: An outstanding tool for metabolic studies|
|Authors:||Rodrigues, Tiago B.|
|Citation:||Concepts in Magnetic Resonance Part A. 27A:1 (2005) 1-16|
|Abstract:||We provide an overview of 13C magnetic resonance spectroscopy methods and their applications as an established metabolic tool with an emphasis on the use of high-resolution 13C magnetic resonance spectroscopy and 13C isotopomer analysis. Topics addressed include general properties of the 13C magnetic resonance spectroscopy spectrum; different 13C magnetic resonance spectroscopy acquisition protocols; determination of fractional 13C enrichment, kinetic, or steady state measurements of metabolic flux; 13C isotopomer analysis approaches; 13C(2H) magnetic resonance spectroscopy methodologies; and in vivo 13C magnetic resonance spectroscopy. Some illustrative applications are described. © 2005 Wiley Periodicals, Inc. Concepts Magn Reson Part A 27A: 1-16, 2005.|
|Appears in Collections:||FCTUC Ciências da Vida - Artigos em Revistas Internacionais|
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