Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/5168
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gonsalves, António M. d'. A. Rocha | - |
dc.contributor.author | Serra, M. Elisa S. | - |
dc.contributor.author | Murtinho, Dina | - |
dc.contributor.author | Silva, Vitor F. | - |
dc.contributor.author | Beja, A. Matos | - |
dc.contributor.author | Paixão, J. A. | - |
dc.contributor.author | Silva, M. Ramos | - |
dc.contributor.author | Veiga, L. Alte da | - |
dc.date.accessioned | 2008-09-01T15:05:07Z | - |
dc.date.available | 2008-09-01T15:05:07Z | - |
dc.date.issued | 2003 | en_US |
dc.identifier.citation | Journal of Molecular Catalysis A: Chemical. 195:1-2 (2003) 1-9 | en_US |
dc.identifier.uri | https://hdl.handle.net/10316/5168 | - |
dc.description.abstract | A series of easily obtained pyrrolidine-based [beta]-amino alcohols derived from tartaric acid and primary amines was synthesized and used as chiral ligands in the enantioselective alkylation of benzaldehyde. Using diethylzinc, 1-phenyl-1-propanol was obtained with enantiomeric excesses of up to 80% when (3S,4S)-N-(1-naphthylmethyl)-3,4-dihydroxypyrrolidine was used. The nature of the N-substituent on the ligand, as well as the reaction temperature proved to significantly influence reaction product distribution as well as the enantiomeric excess of the chiral alcohol. | en_US |
dc.description.uri | http://www.sciencedirect.com/science/article/B6TGM-4790515-2/1/7b585f37987962e55a30bf6583ce3e06 | en_US |
dc.format.mimetype | aplication/PDF | en |
dc.language.iso | eng | eng |
dc.rights | openAccess | eng |
dc.subject | Enantioselective alkylation | en_US |
dc.subject | [beta]-Amino alcohols | en_US |
dc.subject | Diethylzinc | en_US |
dc.subject | Pyrrolidinoalcohols | en_US |
dc.subject | Benzaldehyde | en_US |
dc.title | Pyrrolidine-based amino alcohols: novel ligands for the enantioselective alkylation of benzaldehyde | en_US |
dc.type | article | en_US |
uc.controloAutoridade | Sim | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CFisUC – Center for Physics of the University of Coimbra | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0001-9987-7301 | - |
crisitem.author.orcid | 0000-0002-4562-7072 | - |
crisitem.author.orcid | 0000-0002-1391-9855 | - |
crisitem.author.orcid | 0000-0003-1449-5123 | - |
crisitem.author.orcid | 0000-0003-4634-7395 | - |
crisitem.author.orcid | 0000-0001-9555-8856 | - |
Appears in Collections: | FCTUC Química - Artigos em Revistas Internacionais |
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file4be66d3480154457b85f68956d36d29f.pdf | 118.33 kB | Adobe PDF | View/Open |
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