Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/46914
DC FieldValueLanguage
dc.contributor.authorLobo, Elsa-
dc.contributor.authorSousa, Bruno de-
dc.contributor.authorRosa, Soraia-
dc.contributor.authorFigueiredo, Paula-
dc.contributor.authorLobo, Lis-
dc.contributor.authorPateira, Sara-
dc.contributor.authorFernandes, Natércia-
dc.contributor.authorNogueira, Fátima-
dc.date.accessioned2018-01-26T18:32:40Z-
dc.date.available2018-01-26T18:32:40Z-
dc.date.issued2014-
dc.identifier.urihttp://hdl.handle.net/10316/46914-
dc.description.abstractMozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. The prevalence of pfmdr1 different alleles in Maputo and Mozambique is not known, either after or before the introduction of ACT. Pfmdr1 molecular markers related to Plasmodium falciparum susceptibility were analysed before and after transition to ACT.por
dc.language.isoengpor
dc.rightsopenAccesspor
dc.subjectArtemisininspor
dc.subjectDrug Combinationspor
dc.subjectDrug Resistancepor
dc.subjectEthanolaminespor
dc.subjectFluorenespor
dc.subjectHaplotypespor
dc.subjectHumanspor
dc.subjectMalaria, Falciparumpor
dc.subjectMozambiquepor
dc.subjectMultidrug Resistance-Associated Proteinspor
dc.subjectPlasmodium falciparumpor
dc.subjectPolymorphism, Single Nucleotidepor
dc.subjectPrevalencepor
dc.titlePrevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapypor
dc.typearticlepor
degois.publication.firstPage300por
degois.publication.issue1por
degois.publication.titleMalaria Journalpor
dc.identifier.doi10.1186/1475-2875-13-300-
degois.publication.volume13por
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.openairetypearticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.researchunitCenter for Research in Neuropsychology and Cognitive Behavioral Intervention-
crisitem.author.orcid0000-0001-9918-8100-
Appears in Collections:I&D CINEICC - Artigos em Revistas Internacionais
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