Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/11167| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ferreira, J. A. | - |
| dc.contributor.author | Oliveira, P. de | - |
| dc.contributor.author | Silva, P. M. da | - |
| dc.contributor.author | Carreira, A. | - |
| dc.contributor.author | Gil, H. | - |
| dc.contributor.author | Murta, J. N. | - |
| dc.date.accessioned | 2009-08-26T13:27:38Z | - |
| dc.date.available | 2009-08-26T13:27:38Z | - |
| dc.date.issued | 2009 | - |
| dc.identifier.citation | Pré-Publicações DMUC. 09-20 (2009) | en_US |
| dc.identifier.uri | https://hdl.handle.net/10316/11167 | - |
| dc.description.abstract | This paper focuses on ophthalmic drug release from a loaded copolymer: the drug is dispersed in the polymeric matrix and entrapped in particles. The copolymer is based in 2-hydroxyethyl methacrylate co-methacrylic acid and silicone is used to prepare the loaded particles. A mathematical model to simulate the drug release is proposed and a qualitative analysis is performed. Experimental results are compared with simulation results. Contact lens made from the presented copolymer are expected to deliver drug at therapeutical levels for a few days. | en_US |
| dc.description.sponsorship | Project PTDC/MAT/74548/2006 | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Centro de Matemática da Universidade de Coimbra | en_US |
| dc.rights | openAccess | eng |
| dc.subject | Ophthalmic drug delivery | en_US |
| dc.subject | Contact lenses | en_US |
| dc.subject | p-(HEMA/MAA) | en_US |
| dc.subject | Reaction-diffusion equation | en_US |
| dc.subject | Qualitative behaviour | en_US |
| dc.subject | Numerical simulation | en_US |
| dc.subject | Experimental results | en_US |
| dc.title | Sustained drug released from contact lens | en_US |
| dc.type | preprint | en_US |
| uc.controloAutoridade | Sim | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_816b | - |
| item.openairetype | preprint | - |
| item.cerifentitytype | Publications | - |
| item.grantfulltext | open | - |
| item.fulltext | Com Texto completo | - |
| item.languageiso639-1 | en | - |
| crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
| crisitem.author.orcid | 0000-0001-8926-5176 | - |
| Appears in Collections: | FMUC Medicina - Vários FCTUC Eng.Química - Vários FCTUC Matemática - Vários | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sustained drug released from contact lens.pdf | 3.78 MB | Adobe PDF | View/Open |
Page view(s) 50
416
checked on Apr 16, 2024
Download(s)
85
checked on Apr 16, 2024
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.