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https://hdl.handle.net/10316/110174
Title: | Expressão imunoistoquímica da proteína S-100 na discondroplasia da tíbia | Other Titles: | S-100 protein immunostaining in tibial dyschondroplasia | Authors: | Capela e Silva, F. Lamy, E. Reis, J. C. Potes, J. C. Pereira, A. Cabrita, A. S. |
Keywords: | broiler; tibia; dyschondroplasia; S-100 protein; immunohistochemistry | Issue Date: | 2010 | Publisher: | Universidade de Minas Gerais | Serial title, monograph or event: | Arquivo Brasileiro de Medicina Veterinaria e Zootecnia | Volume: | 62 | Issue: | 2 | Abstract: | It was compared, by immunohistochemistry, the expression of S-100 protein from normal and tibial dyschondroplasia (TD) growth plates. The results suggest that S-100 may be involved in growth plate homeostasis. The expression of S-100 in dyschondroplastic chondrocytes may be due to a low level of calcium in the lesion and/or compression of chondrocytes by the accumulated matrix. One further possibility is the association between S-100 and the regulation of matrix metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs). Further studies will be necessary to provide insight into involvement of S-100 in tibial dyschondroplasia development and the precise nature of the pathology. | URI: | https://hdl.handle.net/10316/110174 | ISSN: | 0102-0935 | DOI: | 10.1590/S0102-09352010000200035 | Rights: | openAccess |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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S100-protein-immunostaining-in-tibial-dyschondroplasiaArquivo-Brasileiro-de-Medicina-Veterinaria-e-Zootecnia.pdf | 314.29 kB | Adobe PDF | View/Open |
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