Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/108062
DC FieldValueLanguage
dc.contributor.authorPars, Selin-
dc.contributor.authorCristo, Fernando-
dc.contributor.authorInácio, José M.-
dc.contributor.authorRosas, Graça-
dc.contributor.authorCarreira, Isabel Marques-
dc.contributor.authorMelo, Joana Barbosa-
dc.contributor.authorMendes, Patrícia-
dc.contributor.authorMartins, Duarte Saraiva-
dc.contributor.authorAlmeida, Luís Pereira de-
dc.contributor.authorMaio, José-
dc.contributor.authorAnjos, Rui-
dc.contributor.authorBelo, José A.-
dc.date.accessioned2023-08-09T08:34:52Z-
dc.date.available2023-08-09T08:34:52Z-
dc.date.issued2018-05-
dc.identifier.issn18735061pt
dc.identifier.urihttps://hdl.handle.net/10316/108062-
dc.description.abstractA DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vitro differentiation potential, karyotype stability, and the transgene-free status of generated iPSC line were analyzed and confirmed. This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease.pt
dc.language.isoengpt
dc.publisherElsevierpt
dc.relationFCT - (PTDC/BIM-MED/3363/2014)pt
dc.relationiNOVA4Health - UID/ Multi/04462/2013, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement is acknowledgedpt
dc.rightsopenAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt
dc.subject.meshCell Linept
dc.subject.meshHumanspt
dc.subject.meshMalept
dc.subject.meshCellular Reprogramming Techniquespt
dc.subject.meshHeart Diseasespt
dc.subject.meshInduced Pluripotent Stem Cellspt
dc.subject.meshIntercellular Signaling Peptides and Proteinspt
dc.titleGeneration and characterization of a human iPS cell line from a patient-related control to study disease mechanisms associated with DAND5 p.R152H alterationpt
dc.typearticle-
degois.publication.firstPage202pt
degois.publication.lastPage206pt
degois.publication.titleStem Cell Researchpt
dc.peerreviewedyespt
dc.identifier.doi10.1016/j.scr.2018.04.015pt
degois.publication.volume29pt
dc.date.embargo2018-05-01*
uc.date.periodoEmbargo0pt
item.grantfulltextopen-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.openairetypearticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextCom Texto completo-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCIBB - Center for Innovative Biomedicine and Biotechnology-
crisitem.author.orcid0000-0001-6842-1707-
crisitem.author.orcid0000-0001-5831-3307-
Appears in Collections:I&D CIBIT - Artigos em Revistas Internacionais
FMUC Medicina - Artigos em Revistas Internacionais
I&D CNC - Artigos em Revistas Internacionais
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