Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105414
DC Field | Value | Language |
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dc.contributor.author | Musilová, Lenka | - |
dc.contributor.author | Mráček, Aleš | - |
dc.contributor.author | Azevedo, Eduarda F. G. | - |
dc.contributor.author | Rodrigo, M. Melia | - |
dc.contributor.author | Valente, Artur J. M. | - |
dc.contributor.author | Esteso, Miguel Á. | - |
dc.contributor.author | Ribeiro, Ana C. F. | - |
dc.date.accessioned | 2023-02-27T10:37:47Z | - |
dc.date.available | 2023-02-27T10:37:47Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 2227-9717 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105414 | - |
dc.description.abstract | Mutual diffusion coefficients of chloroquine diphosphate (CDP) in aqueous solutions both without and with b-cyclodextrin (b-CD) weremeasured at concentrations from(0.0000 to 0.0100)mol dm3 and 298.15 K, using the Taylor dispersion technique. Ternary mutual diffusion coefficients (Dik) measured by the same technique are reported for aqueous CDP + b-CD solutions at 298.15 K. The presence of b CD led to relevant changes in the diffusion process, as showed by nonzero values of the cross-diffusion coefficients, D12 and D21. b-CD concentration gradients produced significant co-current coupled flows of CDP. In addition, the effects of b-CD on the transport of CDP are assessed by comparing the binary diffusion coefficient of aqueous CDP solutions with the main diffusion coefficient (D11) measured for ternary {CDP(1) + b-CD(2)} solutions. These observations are supported by viscosity analysis. All data allow to have a better interpretation on the effect of cyclodextrin on the transport behavior of CDP. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | UID/QUI/UI0313/2019 | pt |
dc.relation | Ministry of Education, Youth and Sports of the Czech Republic DKRVO (RP/CPS/2020/003) | pt |
dc.relation | University of Alcalá (Spain) (Mobility Grants for Researchers-2021) | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | chloroquine diphosphate | pt |
dc.subject | diffusion | pt |
dc.subject | drugs; solutions | pt |
dc.subject | transport properties | pt |
dc.title | Dependence of Viscosity and Diffusion on β-Cyclodextrin and Chloroquine Diphosphate Interactions | pt |
dc.type | article | - |
degois.publication.firstPage | 1433 | pt |
degois.publication.issue | 8 | pt |
degois.publication.title | Processes | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/pr9081433 | pt |
degois.publication.volume | 9 | pt |
dc.date.embargo | 2021-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | Com Texto completo | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-4612-7686 | - |
crisitem.author.orcid | 0000-0001-9736-3999 | - |
crisitem.author.orcid | 0000-0002-3005-1963 | - |
Appears in Collections: | I&D CQC - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Dependence-of-viscosity-and-diffusion-on-cyclodextrin-and-chloroquine-diphosphate-interactionsProcesses.pdf | 517.86 kB | Adobe PDF | View/Open |
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