Peça, João
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Name
Peça, João
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Peca, João
Unidade de I&D
Email
jmpessa@gmail.com
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Status
UC Researcher
Biography
João Peça is a neurobiologist with more than 15 years of research experience. Presently, he is Assistant Professor of Molecular and Cell Biology at the University of Coimbra and Group Leader of the Neuronal Circuits and Behavior Lab. João completed his Ph.D. at Duke University, where he created the first transgenic mice for channelrhodopsin-2 and pioneered the field of optogenetics. He performed postdoctoral research at MIT characterizing animal models for autism, where he uncovered a new role for cortico-striatal dysfunction in autism spectrum disorders. He has completed was supervisor or co-supervisor of 5 Ph.D. students' thesis and of 10+ M.Sc. students. Present interests of his group center on using advanced models to understand how genetic and environmental elements risk factors translate to neurodevelopmental and neuropsychiatric disorders. To achieve this, João uses a combination of molecular genetics, optogenetics and electrophysiological approaches using animal models and human brain organoids. To date his work has led to primary research papers in high-impact, peer-reviewed journals, including Nature, Nature Communications, Molecular Psychiatry, PNAS, and Neuron, and review work in Cell and Annual Reviews in Neuroscience. In 2019 he won "Pfizer Prize in Basic Research", the oldest and one of the most prestigious prizes in Portugal in the area of Biomedical Sciences.
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Results 1-19 of 19 (Search time: 0.042 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 29-Mar-2019 | Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice | Edfawy, Mohamed; Guedes, Joana R. ; Pereira, Marta I. ; Laranjo, Mariana ; Carvalho, Mário J. ; Gao, Xian; Ferreira, Pedro A. ; Caldeira, Gladys ; Franco, Lara O. ; Wang, Dongqing; Cardoso, Ana Luísa ; Feng, Guoping ; Carvalho, Ana Luisa ; Peça, João | article | openAccess |
| 2 | 17-Jul-2023 | Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications | Rebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino | article | openAccess |
| 3 | Sep-2017 | Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles | Santos, Tiago ; Ferreira, Raquel ; Quartin, Emanuel ; Boto, Carlos ; Saraiva, Cláudia ; Bragança, José ; Peça, João ; Rodrigues, Cecília ; Ferreira, Lino ; Bernardino, Liliana | article | openAccess |
| 4 | 2023 | Brain Gain – Discovering Neurosciences: A digital education outreach project for higher education students | Laranjo, Mariana ; Amaral, Sara; Caetano, Carolina; Santos, Sílvio ; Campos, Rita ; Peça, João ; Seabra, Catarina M. | article | openAccess |
| 5 | 22-Dec-2017 | Dissecting the role of GPRASP2 in autism spectrum disorder and intellectual disability | Hussien, Mohamed Edfawy Soliman | doctoralThesis | embargoedAccess |
| 6 | 2016 | Dissection of hierarchy formation in mice: behavioral and molecular correlates of dominance. | Sousa, Renato José Melo | masterThesis | embargoedAccess |
| 7 | 16-Dec-2018 | Effects of a New Bioceramic Material on Human Apical Papilla Cells | Sequeira, Diana B. ; Seabra, Catarina M. ; Palma, Paulo J. ; Cardoso, Ana Luísa ; Peça, João ; Santos, João Miguel | article | openAccess |
| 8 | 2022 | Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications | Rebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino | article | openAccess |
| 9 | 2023 | Engineering optical tools for remotely controlled brain stimulation and regeneration | Rodrigues, Artur Filipe ; Rebelo, Catarina; Reis, Tiago ; Simões, Susana; Bernardino, Liliana; Peça, João ; Ferreira, Lino | article; preprint | embargoedAccess |
| 10 | 30-Oct-2014 | Expression and purification of Channelrhodopsin-2 in Pichia pastoris: generation of blue-shifted and redshifted optogenetic variants | Mazza, Fabio | masterThesis | openAccess |
| 11 | 2015 | "Intelligent design of color-tuned ChR2 variants for optogenetics applications” | Cruz, Bruno Filipe Oereira da | masterThesis | openAccess |
| 12 | 2021 | Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation | Ribeiro, Luís F.; Catarino, Tatiana ; Carvalho, Mário; Cortes, Luísa ; Santos, Sandra D.; Opazo, Patricio O.; Ribeiro, Lyn Rosenbrier; Oliveiros, Bárbara ; Choquet, Daniel; Esteban, José A. ; Peça, João ; Carvalho, Ana Luísa | article | openAccess |
| 13 | 10-Oct-2018 | Long-term impact of early life stress on adult social behavior and prefrontal cortical circuits | Franco, Lara Oliveira | doctoralThesis | embargoedAccess |
| 14 | 6-Mar-2020 | miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's Disease | Barros-Viegas, Ana Teresa ; Carmona, Vitor ; Ferreiro, Elisabete ; Guedes, Joana ; Cardoso, Ana Maria S. ; Cunha, Pedro ; Almeida, Luís Pereira de ; Oliveira, Catarina Resende de ; Magalhães, João Pedro de ; Peça, João ; Cardoso, Ana Luísa | article | openAccess |
| 15 | 2014 | Molecular mechanisms of the synaptic and cognitive effects of ghrelin | Carvalho, Mário Jorge da Silva | masterThesis | openAccess |
| 16 | 21-May-2024 | Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing | Simões, Susana; Lino, Miguel; Barrera, Angela; Rebelo, Catarina; Tomatis, Francesca ; Vilaça, Andreia; Breunig, Christopher; Neuner, Andrea; Peça, João ; González, Ricardo; Carvalho, Alexandra; Stricker, Stefan; Ferreira, Lino | article | openAccess |
| 17 | 9-Aug-2023 | A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia | Martins, Mariana ; Oliveira, Ana Rafaela ; Martins, Solange ; Vieira, José Pedro; Perdigão, Pedro ; Fernandes, Ana Rita; Almeida, Luís Pereira de ; Palma, Paulo Jorge ; Sequeira, Diana Bela ; Santos, João Miguel Marques ; Duque, Frederico ; Oliveira, Guiomar ; Cardoso, Ana Luísa ; Peça, João ; Seabra, Catarina Morais | article | openAccess |
| 18 | 2015 | Optogenetics and biotechnology : production and in vitro characterization of Ab-Initio designed channelrhodopsin-2 mutants | Pereira, João Miguel Calmeiro | masterThesis | openAccess |
| 19 | 2022 | Therapeutic Approaches for Stroke: A Biomaterials Perspective | Rodrigues, Artur Filipe ; Rebelo, Catarina ; Reis, Tiago ; Sousa, João André; Pinho, Sónia L. C.; Sargento-Freitas, João; Peça, João ; Ferreira, Lino | bookPart | embargoedAccess |