This research is sponsored by FEDER funds through the program COMPETE–Programa Operacional Factores de Competitividade and by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding UID/FIS/04650/2019, andUID/EMS/00285/2013 and in the framework of PTDC/CTM-NAN/4242/2014 and PTDC/NAN-MAT/30789/2017. The authors also thank the financial support by the Portuguese Foundation for Science and Technology (FCT) in the framework of the HEALTHYDENT (co-financed via FEDER (PT2020) POCI-01-0145-FEDER-030708 and FCT (PIDDAC) and the NANOXYPACK POCI-01-0145-FEDER-030789 projects. This research was supported by Norte Regional Operational Program 2014-2020 (Norte2020) through the European Regional Development Fund (ERDF) Nanotechnology-based functional solutions (NORTE-01-0145-FEDER-000019) and through European Social Fund (FSE), under the National Doctoral Program in “Surfaces Engineering and Protection”, NORTE-08-5369-FSE-000047. The authors would like to acknowledge the EU Framework Programme for Research and Innovation H2020, scheme COFUND – Co-funding of Regional, National and International Programmes, under Grant Agreement 713640. The CENTRO Program is also acknowledged through the projects MATIS - CENTRO-01-0145-FEDER-000014 and On-Surf - POCI-01-0247-FEDER-024521.