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Issue DateTitleAuthor(s)TypeAccess
12022Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph DiseaseMiranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
27-Jul-2020Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and miceWilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, MatthisarticleopenAccess
38-Feb-2021Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph diseaseDuarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de articleopenAccess
431-Aug-2020The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samplesDuarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de articleopenAccess
52019Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxiaNóbrega, Clévio David Rodrigues ; Mendonça, Liliana Simões ; Marcelo, Adriana Isabel do Vale ; Lamazière, Antonin; Tomé, Sandra Marisa Oliveira ; Despres, Gaetan; Matos, Carlos A; Mechmet, Fatich; Langui, Dominique; den Dunnen, Wilfred; Almeida, Luís Pereira de ; Cartier, Nathalie; Alves, Sandro José Paiva Fernandes articleembargoedAccess
67-Jul-2021Living Proof of Activity of Extracellular Vesicles in the Central Nervous SystemMahjoum, Shadi; Rufino-Ramos, David; Almeida, Luís Pereira de ; Broekman, Marike L. D.; Breakefield, Xandra O.; van Solinge, Thomas S.articleopenAccess
713-Nov-2021Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine DiseasesMoreira, Ricardo ; Mendonça, Liliana Simões ; Almeida, Luís Pereira de articleopenAccess
819-Oct-2021The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh K.; Magni, Stefano; Gérard, Deborah; Antony, Paul M. A.; Nickels, Sarah L.; Salamanca, Luis; Berger, Emanuel; Smits, Lisa M.; Grzyb, Kamil; Perfeito, Rita ; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michèle; Almeida, Luís Pereira de ; Tronstad, Karl J.; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens C.articleopenAccess
98-Jun-2021Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?Marcelo, Adriana ; Koppenol, Rebekah; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio articleopenAccess
109-Apr-2020Trehalose alleviates the phenotype of Machado-Joseph disease mouse modelsSantana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de articleopenAccess
111-Aug-2018Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cellsRodrigues, Carlos F. D. ; Serrano, Eurico ; Patrício, Maria I.; Val, Mariana; Albuquerque, Patrícia; Fonseca, João ; Gomes, Célia M. F. ; Abrunhosa, Antero ; Paiva, Artur ; Carvalho, Lina ; Botelho, Maria F. ; Almeida, Luís ; Carreira, Isabel M. ; Alpoim, Maria Carmen articleopenAccess
125-Dec-2017Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2Hachigian, Lea J.; Carmona, Vitor ; Fenster, Robert J.; Kulicke, Ruth; Heilbut, Adrian; Sittler, Annie; Almeida, Luís Pereira de ; Mesirov, Jill P.; Gao, Fan; Kolaczyk, Eric D.; Heiman, MyriamarticleopenAccess
1311-May-2016Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathwayCunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
142013Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceNóbrega, Clévio ; Nascimento-Ferreira, Isabel ; Onofre, Isabel ; Albuquerque, David ; Hirai, Hirokazu; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
152011Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult ratsSousa-Ferreira, Lígia ; Garrido, Manuel Joaquim Marques ; Nascimento-Ferreira, Isabel ; Nóbrega, Clévio ; Carvalho, Ana dos Santos ; Álvaro, Ana Rita Costa Silva ; Salgado, Joana Rosmaninho ; Kaster, Manuella; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
1611-May-2011Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neuronsSousa-Ferreira, Lígia ; Álvaro, Ana Rita ; Aveleira, Célia ; Santana, Magda ; Brandão, Inês ; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia articleopenAccess
171-Jun-2023The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficitsKoppenol, Rebekah; Conceição, André ; Afonso, Inês T.; Afonso-Reis, Ricardo; Costa, Rafael G.; Tomé, Sandra ; Teixeira, Diogo ; da Silva, Joana Pinto; Codêsso, José Miguel ; Brito, David V. C.; Mendonça, Liliana ; Marcelo, Adriana ; Almeida, Luís Pereira de ; Matos, Carlos A.; Nóbrega, Clévio articleopenAccess
18Dec-2023Ghrelin delays premature aging in Hutchinson-Gilford progeria syndromeFerreira-Marques, Marisa ; Carvalho, André; Franco, Ana Catarina ; Leal, Ana; Botelho, Mariana ; Carmo-Silva, Sara ; Águas, Rodolfo ; Cortes, Luísa ; Lucas, Vasco; Real, Ana Carolina; López-Otín, Carlos; Nissan, Xavier; Almeida, Luís Pereira de ; Cavadas, Cláudia ; Aveleira, Célia A. articleopenAccess
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