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https://hdl.handle.net/10316/8272
Title: | Voltammetric Behavior of Antileukemia Drug Glivec. Part III: In Situ DNA Oxidative Damage by the Glivec Electrochemical Metabolite | Authors: | Diculescu, Victor Constantin Vivan, Marilene Brett, Ana Maria Oliveira |
Issue Date: | 2006 | Citation: | Electroanalysis. 18:19-20 (2006) 1963-1970 | Abstract: | Glivec is a relatively small molecule with activity against the protein tyrosine kinase, a protein expressed by all patients with chronic myelogenous leukemia (CML). Based on its activity on CML, glivec is undergoing extensive evaluation of its activity against other types of tumor. As a result, there is an ongoing need for clarification of glivec pharmacokinetics so that issues such as drug-biomolecular complex interactions can be understood. | URI: | https://hdl.handle.net/10316/8272 | DOI: | 10.1002/elan.200603602 | Rights: | openAccess |
Appears in Collections: | FCTUC Química - Artigos em Revistas Internacionais |
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