Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/7964
Title: | Use of the Post-Insertion Technique to Insert Peptide Ligands into Pre-Formed Stealth Liposomes with Retention of Binding Activity and Cytotoxicity | Authors: | Moreira, João N. Ishida, Tatsuhiro Gaspar, Rogério Allen, Theresa M. |
Issue Date: | 2002 | Citation: | Pharmaceutical Research. 19:3 (2002) 265-269 | Abstract: | Purpose: Simple methods for the large-scale manufacture of ligand-targeted liposomes will be needed if clinical trials are to proceed. We tested a recently developed technology for inserting peptide ligands into preformed Stealth liposomes. Antagonist G-targeted liposomes (PLG) were prepared and loaded with doxorubicin and their cellular association and cytotoxicity were evaluated using the human small cell lung cancer H69 cell line. | URI: | https://hdl.handle.net/10316/7964 | DOI: | 10.1023/A:1014434732752 | Rights: | openAccess |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
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