Title: Ultrasound assisted remote functionalization of non-activated carbon atoms: efficient in situ formation of tetrahydrofurans by sonolysis of bromohydrins with (diacetoxyiodo)benzene/I2
Authors: Costa, Saul C. P. 
Moreno, M. J. S. Miranda 
Melo, M. Luísa Sá e 
Neves, André S. Campos 
Keywords: steroids;tetrahydrofurans;halohydrins;sonochemistry
Issue Date: 1999
Citation: Tetrahedron Letters. 40:49 (1999) 8711-8714
Abstract: Ultrasonic irradiation of bromohydrins in the presence of (diacetoxyiodo)benzene and I2 generates alkoxyl radicals which lead in situ to intramolecular hydrogen abstraction on the C-19 non-activated carbon atoms in steroids producing tetrahydrofurans selectively in very good yields. Photolysis was less effective in promoting such conversions.
URI: http://hdl.handle.net/10316/5815
Rights: openAccess
Appears in Collections:FFUC- Artigos em Revistas Internacionais

Files in This Item:
File Description SizeFormat 
filec7158fc3f6754120a992f706aacd2c63.pdf258.92 kBAdobe PDFView/Open
Show full item record
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.