Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/5791
Title: | Antimalarial activity of medicinal plants used in traditional medicine in S. Tomé and Príncipe islands | Authors: | Madureira, Maria do Céu de Martins, Ana Paula Gomes, Milene Paiva, Jorge Cunha, António Proença da Rosário, Virgílio do |
Keywords: | Antimalarial activity; Medicinal plants; Struchium sparganophorum; Tithonia diversifolia; Pycnanthus angolensis; Morinda lucida | Issue Date: | 2002 | Citation: | Journal of Ethnopharmacology. 81:1 (2002) 23-29 | Abstract: | The present study investigates the antimalarial activity of 13 medicinal plants used in traditional medicine in S. Tomé and Príncipe (STP) islands in the Gulf of Guinea, aiming at identifying the most effective plants for further research. Fieldwork was carried out with the collaboration of 37 traditional healers from both islands, during an ethnobotanical study, which was conducted from 1993 to 1999. Our results indicate that the traditional healers in STP use several medicinal plants against fever and/or [`]malaria' which reveal strong antiparasitic activity in vitro: four of the plant extracts have evident antiplasmodial activity against chloroquine resistant Plasmodium falciparum, with IC50 values <10 [mu]g/ml, and also revealed hepatic schizontocidal activity (<5-35 [mu]g/ml). In vivo, the extracts caused partial reduction of Plasmodium berghei parasitaemia in mice. | URI: | https://hdl.handle.net/10316/5791 | DOI: | 10.1016/S0378-8741(02)00005-3 | Rights: | openAccess |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
fileca12fee15fc842cd9c635f3e18ca8c08.pdf | 105.74 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
132
checked on Oct 7, 2024
WEB OF SCIENCETM
Citations
110
checked on Oct 2, 2024
Page view(s) 50
532
checked on Oct 8, 2024
Download(s) 10
2,041
checked on Oct 8, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.