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Title: Risk for autism and parent’s age and education level?
Authors: Alferes, Daniela Patrícia Gomes 
Orientador: Duque, Frederico de Oliveira
Oliveira, Guiomar
Keywords: Autism spectrum disorder; Neurodevelopmental disorders; Parental age; Parental education
Issue Date: May-2016
Abstract: We investigated the influence of advanced parental age in Autism Spectrum Disorder (ASD) and other Neurodevelopmental Disorders (OND), also comparing with data of Portuguese population. Participated 1973 children and adolescents: ASD (N=1202) and OND (N=771). Parental ages were divided into four categories. Comparison of parental age between clinical groups and with population data was performed using t-Student tests. Odds ratios and confidence intervals were estimated using logistic regression analysis, adjusted for risk factors. We found statistically significant differences between maternal ages of ASD and OND children, but not between paternal ages. The impact of advanced maternal age was higher in ASD than OND, although influencing both. There is an increase in mean maternal age at birth over the years, with values higher than population data. Older maternal age and parental education was independently associated with increased odds of ASD.
Description: Trabalho final do 6º ano médico com vista à atribuição do grau de mestre (área científica de pediatria) no âmbito do ciclo de estudos de Mestrado Integrado em Medicina.
Rights: openAccess
Appears in Collections:FMUC Medicina - Teses de Mestrado
UC - Dissertações de Mestrado

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