Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/114492
DC Field | Value | Language |
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dc.contributor.author | Sousa-Pinto, B | - |
dc.contributor.author | Louis, R | - |
dc.contributor.author | Anto, J M | - |
dc.contributor.author | Amaral, R | - |
dc.contributor.author | Sá-Sousa, A | - |
dc.contributor.author | Czarlewski, W | - |
dc.contributor.author | Brussino, L | - |
dc.contributor.author | Canonica, G W | - |
dc.contributor.author | Chaves Loureiro, C | - |
dc.contributor.author | Cruz, A A | - |
dc.contributor.author | Gemicioglu, B | - |
dc.contributor.author | Haahtela, T | - |
dc.contributor.author | Kupczyk, M | - |
dc.contributor.author | Kvedariene, V | - |
dc.contributor.author | Larenas-Linnemann, D E | - |
dc.contributor.author | Okamoto, Y | - |
dc.contributor.author | Ollert, M | - |
dc.contributor.author | Pfaar, O | - |
dc.contributor.author | Pham-Thi, N | - |
dc.contributor.author | Puggioni, F | - |
dc.contributor.author | Regateiro, F. S. | - |
dc.contributor.author | Romantowski, J | - |
dc.contributor.author | Sastre, J | - |
dc.contributor.author | Scichilone, N | - |
dc.contributor.author | Taborda-Barata, L | - |
dc.contributor.author | Ventura, M T | - |
dc.contributor.author | Agache, I | - |
dc.contributor.author | Bedbrook, A | - |
dc.contributor.author | Becker, S | - |
dc.contributor.author | Bergmann, K C | - |
dc.contributor.author | Bosnic-Anticevich, S | - |
dc.contributor.author | Bonini, M | - |
dc.contributor.author | Boulet, L-P | - |
dc.contributor.author | Brusselle, G | - |
dc.contributor.author | Buhl, R | - |
dc.contributor.author | Cecchi, L | - |
dc.contributor.author | Charpin, D | - |
dc.contributor.author | de Blay, F | - |
dc.contributor.author | Del Giacco, S | - |
dc.contributor.author | Ivancevich, J C | - |
dc.contributor.author | Jutel, M | - |
dc.contributor.author | Klimek, L | - |
dc.contributor.author | Kraxner, H | - |
dc.contributor.author | Kuna, P | - |
dc.contributor.author | Laune, D | - |
dc.contributor.author | Makela, M | - |
dc.contributor.author | Morais-Almeida, M | - |
dc.contributor.author | Nadif, R | - |
dc.contributor.author | Niedoszytko, M | - |
dc.contributor.author | Papadopoulos, N G | - |
dc.contributor.author | Papi, A | - |
dc.contributor.author | Patella, V | - |
dc.contributor.author | Pétré, B | - |
dc.contributor.author | Rivero Yeverino, D | - |
dc.contributor.author | Cordeiro, Carlos Robalo | - |
dc.contributor.author | Roche, N | - |
dc.contributor.author | Rouadi, P W | - |
dc.contributor.author | Samolinski, B | - |
dc.contributor.author | Savouré, M | - |
dc.contributor.author | Shamji, M H | - |
dc.contributor.author | Sheikh, A | - |
dc.contributor.author | Suppli Ulrik, C | - |
dc.contributor.author | Usmani, O S | - |
dc.contributor.author | Valiulis, A | - |
dc.contributor.author | Yorgancioglu, A | - |
dc.contributor.author | Fonseca, J A | - |
dc.contributor.author | Costa, E M | - |
dc.contributor.author | Bousquet, J | - |
dc.date.accessioned | 2024-03-28T12:54:55Z | - |
dc.date.available | 2024-03-28T12:54:55Z | - |
dc.date.issued | 2023-08-03 | - |
dc.identifier.issn | 25310437 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/114492 | - |
dc.description.abstract | Introduction: Adherence to controller medication is a major problem in asthma management, being difficult to assess and tackle. mHealth apps can be used to assess adherence. We aimed to assess the adherence to inhaled corticosteroids+long-acting β2-agonists (ICS+LABA) in users of the MASK-air® app, comparing the adherence to ICS+formoterol (ICS+F) with that to ICS+other LABA. Materials and methods: We analysed complete weeks of MASK-air® data (2015-2022; 27 countries) from patients with self-reported asthma and ICS+LABA use. We compared patients reporting ICS+F versus ICS+other LABA on adherence levels, symptoms and symptom-medication scores. We built regression models to assess whether adherence to ICS+LABA was associated with asthma control or short-acting beta-agonist (SABA) use. Sensitivity analyses were performed considering the weeks with no more than one missing day. Results: In 2598 ICS+LABA users, 621 (23.9%) reported 4824 complete weeks and 866 (33.3%) reported weeks with at most one missing day. Higher adherence (use of medication ≥80% of weekly days) was observed for ICS+other LABA (75.1%) when compared to ICS+F (59.3%), despite both groups displaying similar asthma control and work productivity. The ICS+other LABA group was associated with more days of SABA use than the ICS+F group (median=71.4% versus 57.1% days). Each additional weekly day of ICS+F use was associated with a 4.1% less risk in weekly SABA use (95%CI=-6.5;-1.6%;p=0.001). For ICS+other LABA, the percentage was 8.2 (95%CI=-11.6;-5.0%;p<0.001). Conclusions: In asthma patients adherent to the MASK-air app, adherence to ICS+LABA was high. ICS+F users reported lower adherence but also a lower SABA use and a similar level of control. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | Asthma | pt |
dc.subject | Adherence | pt |
dc.subject | Inhaledcorticosteroids | pt |
dc.subject | Formoterol | pt |
dc.subject | Long-acting-b2agonist | pt |
dc.title | Adherence to inhaled corticosteroids and long-acting β2-agonists in asthma: A MASK-air study | pt |
dc.type | article | - |
degois.publication.title | Pulmonology | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.pulmoe.2023.07.004 | pt |
dc.date.embargo | 2023-08-03 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | Com Texto completo | - |
crisitem.author.researchunit | iNOVA4Health - Programme in Translational Medicine (iBET, CEDOC/FCM, IPOLFG and ITQB) | - |
crisitem.author.orcid | 0000-0002-8264-3856 | - |
Appears in Collections: | I&D CIBB - Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Adherence to inhaled corticosteroids and long-acting β2-agonists in asthma A MASK-air study.pdf | 642.64 kB | Adobe PDF | View/Open |
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