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https://hdl.handle.net/10316/113732| Title: | The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study | Authors: | Jiskoot, Lize C. Russell, Lucy L. Peakman, Georgia Convery, Rhian S. Greaves, Caroline V. Bocchetta, Martina Poos, Jackie M. Seelaar, Harro Giannini, Lucia A. A. van Swieten, John C. van Minkelen, Rick Pijnenburg, Yolande A. L. Rowe, James B. Borroni, Barbara Galimberti, Daniela Masellis, Mario Tartaglia, Carmela Finger, Elizabeth Butler, Chris R. Graff, Caroline Laforce, Robert Sánchez-Valle, Raquel de Mendonça, Alexandre Moreno, Fermin Synofzik, Matthis Vandenberghe, Rik Ducharme, Simon le Ber, Isabelle Levin, Johannes Otto, Markus Pasquier, Florence Santana, Isabel Cash, David M. Thomas, David Rohrer, Jonathan D. |
Keywords: | Frontotemporal dementia; Cognition; Neuropsychology; Genetic; Presymptomatic; Marker | Issue Date: | 15-Mar-2023 | Publisher: | Elsevier | Project: | The Dementia Research Centre is supported by Alzheimer’s Research UK, Alzheimer’s Society, Brain Research UK, and The Wolfson Foundation. This work was supported by the NIHR UCL/H Biomedical Research Centre, the Leonard Wolfson Experimental Neurology Centre (LWENC) Clinical Research Facility, and the UK Dementia Research Institute, which receives its funding from UK DRI Ltd., funded by the UK Medical Research Council, Alzheimer’s Society and Alzheimer’s Research UK. JDR is supported by the Miriam Marks Brain Research UK Senior Fellowship and has received funding from an MRC Clinician Scientist Fellowship (MR/M008525/1) and the NIHR Rare Disease Translational Research Collaboration (BRC149/NS/MH). This work was also supported by the MRC UK GENFI grant (MR/M023664/1), the Bluefield Project, the JPND GENFI-PROX grant (2019–02248), the Dioraphte Foundation [grant numbers 09–02-00], the Association for Frontotemporal Dementias Research Grant 2009, The Netherlands Organization for Scientific Research (NWO) (grant HCMI 056–13-018), ZonMw Memorabel (Deltaplan Dementie; project numbers 733050103 and 733050813), JPND PreFrontAls Consortium (project number 733051042) and Instituto de Salud Carlos III, Spain, and FEDER funds (grant number 20/00448). JBR is supported by the Wellcome Trust (103838), Medical Research Council (SUAG092 G116768) and the NIHR Cambridge Biomedical Research Centre (BRC-1215 20014: the views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care). This work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy within the framework of the Munich Cluster for Systems Neurology (EXC 2145 SyNergy – ID 390857198). JMP is supported by a fellowship award from Alzheimer Nederland (WE.15–2019.02). This work was conducted using the MRC Dementias Platform UK (MR/L023784/1 and MR/009076/1). | Serial title, monograph or event: | Journal of the Neurological Sciences | Volume: | 446 | Abstract: | Sensitive cognitive markers are still needed for frontotemporal dementia (FTD). The Benson Complex Figure Test (BCFT) is an interesting candidate test, as it assesses visuospatial, visual memory, and executive abilities, allowing the detection of multiple mechanisms of cognitive impairment. To investigate differences in BCFT Copy, Recall and Recognition in presymptomatic and symptomatic FTD mutation carriers, and to explore its cognitive and neuroimaging correlates. | URI: | https://hdl.handle.net/10316/113732 | ISSN: | 0022510X | DOI: | 10.1016/j.jns.2023.120590 | Rights: | openAccess |
| Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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| The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia.pdf | 3.4 MB | Adobe PDF | View/Open |
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