Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113678
DC Field | Value | Language |
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dc.contributor.author | Boboridis, Kostas G. | - |
dc.contributor.author | Messmer, Elisabeth M. | - |
dc.contributor.author | Benítez-Del-Castillo, José | - |
dc.contributor.author | Meunier, Juliette | - |
dc.contributor.author | Sloesen, Brigitte | - |
dc.contributor.author | O'Brien, Paul | - |
dc.contributor.author | Quadrado, Maria João | - |
dc.contributor.author | Rolando, Maurizio | - |
dc.contributor.author | Labetoulle, Marc | - |
dc.date.accessioned | 2024-02-26T12:17:09Z | - |
dc.date.available | 2024-02-26T12:17:09Z | - |
dc.date.issued | 2023-03-17 | - |
dc.identifier.issn | 2044-6055 | pt |
dc.identifier.issn | 2044-6055 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/113678 | - |
dc.description.abstract | Objective Dry eye disease (DED) is a multifactorial disease involving the tears and ocular surface. It impacts a patient’s quality of life (QoL) and ability to perform daily activities. This study assessed the burden of self-reported DED among adults in eight European countries. Design Online cross-sectional survey. Setting General population in France, Italy, Germany, Greece, the Netherlands, Portugal, Spain and Sweden. Participants Adults aged ≥18 years with (n=6084) and without (n=6161) self-reported DED were recruited via emails and screened. Main outcome measures All participants completed National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ- 25) and EuroQol-5 Dimension-5 Level Questionnaire (EQ-5D- 5L). All DED participants completed the Eye Dryness Score (EDS) Visual Analogue Scale, and Ocular Comfort Index and Work Productivity and Activity Impairment Questionnaire: Specific Health Problem questionnaires. In addition, half of the respondents with DED completed Survey A (Impact of Dry Eye on Everyday Life) and the other half completed Survey B (Standard Patient Evaluation of Eye Dryness Questionnaire) and Dry Eye Questionnaire-5. Results Participants with self-reported DED had lower functional vision and lower overall health status than participants without self-reported DED as measured by the NEI-VFQ and EQ-5D- 5L, respectively. Increasing self-reported DED severity as measured by the EDS was shown to correspond with worse symptom severity/frequency, lower functional vision, higher impact on work productivity, daily activities and QoL. Conclusion This study showed that patients’ reported burden of self-reported DED was similar across the eight European countries. Those with self-reported DED reported lower health status and functional vision compared to those without self-reported DED and these parameters worsen with increasing disease severity. | pt |
dc.language.iso | eng | pt |
dc.publisher | BMJ Publishing Group | pt |
dc.relation | Novartis | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt |
dc.subject | corneal and external diseases | pt |
dc.subject | epidemiology | pt |
dc.subject | ophthalmology | pt |
dc.subject | primary care | pt |
dc.subject | public health | pt |
dc.subject.mesh | Adult | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | Adolescent | pt |
dc.subject.mesh | Cross-Sectional Studies | pt |
dc.subject.mesh | Surveys and Questionnaires | pt |
dc.subject.mesh | Patient Reported Outcome Measures | pt |
dc.subject.mesh | Internet | pt |
dc.subject.mesh | Quality of Life | pt |
dc.subject.mesh | Dry Eye Syndromes | pt |
dc.title | Patient-reported burden and overall impact of dry eye disease across eight European countries: a cross-sectional web-based survey | pt |
dc.type | article | - |
degois.publication.firstPage | e067007 | pt |
degois.publication.issue | 3 | pt |
degois.publication.title | BMJ Open | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1136/bmjopen-2022-067007 | pt |
degois.publication.volume | 13 | pt |
dc.date.embargo | 2023-03-17 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | A Novartis foca a sua atividade em duas divisões com poder de inovação e dimensão global: farmacêutica e medicamentos genéricos e biossimilares- Portugal | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Patientreported-burden-and-overall-impact-of-dry-eye-disease-across-eight-European-countries-a-crosssectional-webbased-surveyBMJ-Open.pdf | 1.42 MB | Adobe PDF | View/Open |
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This item is licensed under a Creative Commons License