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https://hdl.handle.net/10316/113590| Title: | Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses | Authors: | Thayallath, Sarath Kumar Shet, Sachin M. Bisht, Meena Bharadwaj, Pranav Pereira, Matheus M. Franklin, Gregory Nataraj, S. K. Mondal, Dibyendu |
Issue Date: | 11-May-2023 | Publisher: | Royal Society of Chemistry | Project: | This work was supported by the National Science Centre (NCN), SONATA project no Reg. UMO-2021/43/D/ST4/00699. DM and GF acknowledge the NANOPLANT project, which received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement no. 856961. DM also thanks SERB grant (EEQ/2021/000059) for financial support. MP acknowledges CIEPQPF which is supported by the FCT through the projects UIDB/EQU/00102/2020 and UIDP/EQU/00102/2020. | Serial title, monograph or event: | Chemical Communications | Volume: | 59 | Issue: | 39 | Abstract: | Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome C (Cyt C) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt C nanoconstruct (Cyt C + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt C and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy. | URI: | https://hdl.handle.net/10316/113590 | DOI: | 10.1039/d3cc00644a | Rights: | openAccess |
| Appears in Collections: | FCTUC Eng.Química - Artigos em Revistas Internacionais I&D CIEPQPF - Artigos em Revistas Internacionais |
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