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Title: | Patient-centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA-EAACI approach - ARIA-EAACI Task Force Report | Authors: | Bousquet, Jean Shamji, Mohamed H. Anto, Josep M. Schünemann, Holger J. Canonica, G. Walter Jutel, Marek Del Giacco, Stefano Zuberbier, Torsten Pfaar, Oliver Fonseca, Joao A. Sousa-Pinto, Bernardo Klimek, Ludger Czarlewski, Wienczyslawa Bedbrook, Anna Amaral, Rita Ansotegui, Ignacio J. Bosnic-Anticevich, Sinthia Braido, Fulvio Chaves Loureiro, Cláudia Gemicioglu, Bilun Haahtela, Tari Kulus, Marek Kuna, Piotr Kupczyk, Maciej Matricardi, Paolo M. Regateiro, Frederico S. Samolinski, Boleslaw Sofiev, Mikhail Toppila-Salmi, Sanna Valiulis, Arunas Ventura, Maria Teresa Barbara, Cristina Bergmann, Karl C. Bewick, Michael Blain, Hubert Bonini, Matteo Boulet, Louis-Philippe Bourret, Rodolphe Brusselle, Guy Brussino, Luisa Buhl, Roland Cardona, Victoria Casale, Thomas Cecchi, Lorenzo Charpin, Denis Cherrez-Ojeda, Ivan Chu, Derek K. Cingi, Cemal Costa, Elisio M. Cruz, Alvaro A. Devillier, Philippe Dramburg, Stephanie Fokkens, Wytske J. Gotua, Maia Heffler, Enrico Ispayeva, Zhanat Ivancevich, Juan Carlos Joos, Guy Kaidashev, Igor Kraxner, Helga Kvedariene, Violeta Larenas-Linnemann, Désirée E. Laune, Daniel Lourenço, Olga Louis, Renaud Makela, Mika Makris, Michael Maurer, Marcus Melén, Erik Micheli, Yann Morais-Almeida, Mario Mullol, Joaquim Niedoszytko, Marek O'Hehir, Robyn Okamoto, Yoshitaka Olze, Heidi Papadopoulos, Nikolaos G. Papi, Alberto Patella, Vincenzo Pétré, Benoit Pham-Thi, Nhân Puggioni, Francesca Quirce, Santiago Roche, Nicolas Rouadi, Philip W. Sá-Sousa, Ana Sagara, Hironori Sastre, Joaquin Scichilone, Nicola Sheikh, Aziz Sova, Milan Suppli Ulrik, Charlotte Taborda-Barata, Luis Todo-Bom, Ana Torres, Maria J. Tsiligianni, Ioanna Usmani, Omar S. Valovirta, Erkka Vasankari, Tuula Vieira, Rafael José Wallace, Dana Waserman, Susan Zidarn, Mihaela Yorgancioglu, Arzu Zhang, Luo Chivato, Tomas Ollert, Markus |
Keywords: | apps; ARIA; digital health; EAACI; rhinitis | Issue Date: | Jul-2023 | Publisher: | Wiley-Blackwell | Serial title, monograph or event: | Allergy: European Journal of Allergy and Clinical Immunology | Volume: | 78 | Issue: | 7 | Abstract: | Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of-life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed. | URI: | https://hdl.handle.net/10316/112371 | ISSN: | 0105-4538 1398-9995 |
DOI: | 10.1111/all.15740 | Rights: | openAccess |
Appears in Collections: | I&D ICBR - Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
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