Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/109277
Title: | Multilevel Approach of a 1-Year Program of Dietary and Exercise Interventions on Bone Mineral Content and Density in Metabolic Syndrome--the RESOLVE Randomized Controlled Trial | Authors: | Courteix, Daniel Valente-dos-Santos, João Ferry, Béatrice Lac, Gérard Lesourd, Bruno Chapier, Robert Naughton, Geraldine Marceau, Geoffroy Coelho-e-Silva, Manuel João Vinet, Agnès Walther, Guillaume Obert, Philippe Dutheil, Frédéric |
Issue Date: | 2015 | Publisher: | Public Library of Science | Project: | Heart and Arteries Foundation (Fondation Coeur et Artères) 59200 Loos, France; www.fondacoeur.com. SFRH/BPD/100470/2014 |
Serial title, monograph or event: | PLoS ONE | Volume: | 10 | Issue: | 9 | Abstract: | Weight loss is a public health concern in obesity-related diseases such as metabolic syndrome (MetS). However, restrictive diets might induce bone loss. The nature of exercise and whether exercise with weight loss programs can protect against potential bone mass deficits remains unclear. Moreover, compliance is essential in intervention programs. Thus, we aimed to investigate the effects that modality and exercise compliance have on bone mineral content (BMC) and density (BMD). Methods We investigated 90 individuals with MetS who were recruited for the 1-year RESOLVE trial. Community-dwelling seniors with MetS were randomly assigned into three different modalities of exercise (intensive resistance, intensive endurance, moderate mixed) combined with a restrictive diet. They were compared to 44 healthy controls who did not undergo the intervention. Results This intensive lifestyle intervention (15–20 hours of training/week + restrictive diet) resulted in weight loss, body composition changes and health improvements. Baseline BMC and BMD for total body, lumbar spine and femoral neck did not differ between MetS groups and between MetS and controls. Despite changes over time, BMC or BMD did not differ between the three modalities of exercise and when compared with the controls. However, independent of exercise modality, compliant participants increased their BMC and BMD compared with their less compliant peers. Decreases in total body lean mass and negative energy balance significantly and independently contributed to decreases in lumbar spine BMC. Conclusion After the one year intervention, differences relating to exercise modalities were not evident. However, compliance with an intensive exercise program resulted in a significantly higher bone mass during energy restriction than non-compliance. Exercise is therefore beneficial to bone in the context of a weight loss program. | URI: | https://hdl.handle.net/10316/109277 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0136491 | Rights: | openAccess |
Appears in Collections: | FCDEF - Artigos em Revistas Internacionais I&D CIDAF - Artigos em Revistas Internacionais |
Files in This Item:
SCOPUSTM
Citations
16
checked on Oct 7, 2024
WEB OF SCIENCETM
Citations
17
checked on Oct 2, 2024
Page view(s)
133
checked on Oct 16, 2024
Download(s)
39
checked on Oct 16, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License