Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/109265
DC Field | Value | Language |
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dc.contributor.author | Menger, David J. | - |
dc.contributor.author | Omusula, Philemon | - |
dc.contributor.author | Holding, Maarten | - |
dc.contributor.author | Homan, Tobias | - |
dc.contributor.author | Carreira, Ana S. | - |
dc.contributor.author | Vandendaele, Patrice | - |
dc.contributor.author | Derycke, Jean-Luc | - |
dc.contributor.author | Mweresa, Collins K. | - |
dc.contributor.author | Mukabana, Wolfgang Richard | - |
dc.contributor.author | van Loon, Joop J. A. | - |
dc.contributor.author | Takken, Willem | - |
dc.date.accessioned | 2023-10-06T10:01:52Z | - |
dc.date.available | 2023-10-06T10:01:52Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1932-6203 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/109265 | - |
dc.description.abstract | Malaria continues to place a disease burden on millions of people throughout the tropics, especially in sub-Saharan Africa. Although efforts to control mosquito populations and reduce human-vector contact, such as long-lasting insecticidal nets and indoor residual spraying, have led to significant decreases in malaria incidence, further progress is now threatened by the widespread development of physiological and behavioural insecticide-resistance as well as changes in the composition of vector populations. A mosquito-directed push-pull system based on the simultaneous use of attractive and repellent volatiles offers a complementary tool to existing vector-control methods. In this study, the combination of a trap baited with a five-compound attractant and a strip of net-fabric impregnated with micro-encapsulated repellent and placed in the eaves of houses, was tested in a malaria-endemic village in western Kenya. Using the repellent delta-undecalactone, mosquito house entry was reduced by more than 50%, while the traps caught high numbers of outdoor flying mosquitoes. Model simulations predict that, assuming area-wide coverage, the addition of such a push-pull system to existing prevention efforts will result in up to 20-fold reductions in the entomological inoculation rate. Reductions of such magnitude are also predicted when mosquitoes exhibit a high resistance against insecticides. We conclude that a push-pull system based on non-toxic volatiles provides an important addition to existing strategies for malaria prevention. | pt |
dc.language.iso | eng | pt |
dc.publisher | Public Library of Science | pt |
dc.relation | The laboratory work was funded by the European Union through NMP2-2009-228639, FP7, NOBUG project; the fieldwork was funded by a grant from the Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative (GCGH#121). Ana S. Carreira gratefully acknowledges the Fundação para a Ciência e Tecnologia, Portugal, for the financial support under the PhD grant (SFRH/BDE/51601/2011), which includes the encapsulation work. Devan Chemicals and Utexbel provided support in the form of salaries | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject.mesh | Animals | pt |
dc.subject.mesh | Anopheles | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | Insect Vectors | pt |
dc.subject.mesh | Insecticide Resistance | pt |
dc.subject.mesh | Insecticide-Treated Bednets | pt |
dc.subject.mesh | Insecticides | pt |
dc.subject.mesh | Kenya | pt |
dc.subject.mesh | Malaria | pt |
dc.subject.mesh | Mosquito Control | pt |
dc.title | Field evaluation of a push-pull system to reduce malaria transmission | pt |
dc.type | article | - |
degois.publication.firstPage | e0123415 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | PLoS ONE | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1371/journal.pone.0123415 | pt |
degois.publication.volume | 10 | pt |
dc.date.embargo | 2015-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.openairetype | article | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | I&D CERES - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Field-evaluation-of-a-pushpull-system-to-reduce-malaria-transmissionPLoS-ONE.pdf | 4.23 MB | Adobe PDF | View/Open |
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This item is licensed under a Creative Commons License