Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/107492
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Caneiras, Cátia | - |
dc.contributor.author | Calisto, Filipa | - |
dc.contributor.author | Silva, Gabriela Jorge da | - |
dc.contributor.author | Lito, Luis | - |
dc.contributor.author | Melo-Cristino, José | - |
dc.contributor.author | Duarte, Aida | - |
dc.date.accessioned | 2023-07-14T11:06:27Z | - |
dc.date.available | 2023-07-14T11:06:27Z | - |
dc.date.issued | 2018-11-06 | - |
dc.identifier.issn | 2079-6382 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/107492 | - |
dc.description.abstract | Herein, we describe a case report of carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae isolates that were identified from the same patient at a Tertiary University Hospital Centre in Portugal. Antimicrobial susceptibility and the molecular characterization of resistance and virulence determinants were performed. PCR screening identified the presence of the resistance genes blaKPC-3, blaTEM-1 and blaSHV-1 in both isolates. The KPC-3 K. pneumoniae isolate belonged to the ST-14 high risk clone and accumulated an uncommon resistance and virulence profile additional to a horizontal dissemination capacity. In conclusion, the molecular screening led to the first identification of the A. baumannii KPC-3 producer in Portugal with a full antimicrobial resistance profile including tigecycline and colistin. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | antimicrobial resistance | pt |
dc.subject | Gram-negative bacteria | pt |
dc.subject | K. pneumoniae | pt |
dc.subject | A. baumannii | pt |
dc.subject | KPC-3 carbapenemase | pt |
dc.subject | colistin | pt |
dc.subject | tigecycline | pt |
dc.title | First Description of Colistin and Tigecycline-Resistant Acinetobacter baumannii Producing KPC-3 Carbapenemase in Portugal | pt |
dc.type | article | - |
degois.publication.firstPage | 96 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | Antibiotics | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/antibiotics7040096 | pt |
degois.publication.volume | 7 | pt |
dc.date.embargo | 2018-11-06 | * |
uc.date.periodoEmbargo | 0 | pt |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.openairetype | article | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0002-7479-8540 | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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First-description-of-colistin-and-tigecyclineresistant-acinetobacter-baumannii-producing-KPC3-carbapenemase-in-PortugalAntibiotics.pdf | 285.85 kB | Adobe PDF | View/Open |
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